Skip to main content Accessibility help
×
Home

Misattribution bias of threat-related facial expressions is related to a longer duration of illness and poor executive function in schizophrenia and schizoaffective disorder

  • Preethi Premkumar (a1), Michael A. Cooke (a1), Dominic Fannon (a2), Emmanuelle Peters (a1), Tanja M. Michel (a3) (a4), Ingrid Aasen (a1), Robin M. Murray (a2), Elizabeth Kuipers (a1) and Veena Kumari (a1)...

Abstract

Background

While it is known that patients with schizophrenia recognize facial emotions, specifically negative emotions, less accurately, little is known about how they misattribute these emotions to other emotions and whether such misattribution biases are associated with symptoms, course of the disorder, or certain cognitive functions.

Method

Outpatients with schizophrenia or schizoaffective disorder (n = 73) and healthy controls (n = 30) performed a computerised Facial Emotion Attribution Test and Wisconsin Card Sorting Test (WCST). Patients were also rated on the Positive and Negative Syndrome Scale (PANSS).

Results

Patients were poor at recognizing fearful and angry emotions and attributed fear to angry and angry to neutral expressions. Fear-as-anger misattributions were predicted independently by a longer duration of illness and WCST perseverative errors.

Conclusion

The findings show a bias towards misattributing fearful and angry facial emotions. The propensity for fear-as-anger misattribution biases increases as the length of time that the disorder is experienced increases and a more rigid style of information processing is used. This, at least in part, may be perpetuated by subtle fearfulness expressed by others while interacting with people with schizophrenia.

  • View HTML
    • Send article to Kindle

      To send this article to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle. Find out more about sending to your Kindle.

      Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

      Find out more about the Kindle Personal Document Service.

      Misattribution bias of threat-related facial expressions is related to a longer duration of illness and poor executive function in schizophrenia and schizoaffective disorder
      Available formats
      ×

      Send article to Dropbox

      To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Dropbox.

      Misattribution bias of threat-related facial expressions is related to a longer duration of illness and poor executive function in schizophrenia and schizoaffective disorder
      Available formats
      ×

      Send article to Google Drive

      To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Google Drive.

      Misattribution bias of threat-related facial expressions is related to a longer duration of illness and poor executive function in schizophrenia and schizoaffective disorder
      Available formats
      ×

Copyright

Open access under CC BY-NC-ND license.

Corresponding author

*Corresponding author. Tel.: +44 207 848 5102; fax: +44 207 848 0860.

References

Hide All
[1]Abdi, Z., Sharma, T.Social cognition and its neural correlates in schizophrenia and autism. CNS Spectr 2004;9(5):335343.
[2]Addington, J., Addington, D.Facial affect recognition and information processing in schizophrenia and bipolar disorder. Schizophr Res 1998;32(3):171181.
[3]Bentall, R.P., Corcoran, R., Howard, R., Blackwood, N., Kinderman, P.Persecutory delusions: a review and theoretical integration. Clin Psychol Rev 2001;21:11431192.
[4]Borod, J.C., Martin, C.C., Alpert, M., Brozgold, A., Welkowitz, J.Perception of facial emotion in schizophrenic and right brain-damaged patients. J Nerv Ment Dis 1993;181(8):494502.
[5]Bozikas, V.P., Kosmidis, M.H., Anezoulaki, D., Giannakou, M., Karavatos, A.Relationship of affect recognition with psychopathology and cognitive performance in schizophrenia. J Int Neuropsychol Soc 2004;10(4):549559.
[6]Brune, M.Emotion recognition, ‘theory of mind,’ and social behavior in schizophrenia. Psychiatry Res 2005;133(2–3):135147.
[7]Craig, J.S., Hatton, C., Craig, F.B., Bentall, R.P.Persecutory beliefs, attributions and theory of mind: comparison of patients with paranoid delusions, Asperger's syndrome and healthy controls. Schizophr Res 2004;69(1):2933.
[8]Das, P., Kemp, A.H., Flynn, G., Harris, A.W., Liddell, B.J., Whitford, T.J.et al.Functional disconnections in the direct and indirect amygdala pathways for fear processing in schizophrenia. Schizophr Res 2007;90(1–3):284294.
[9]de Gelder, B., Vroomen, J., de Jong, S.J., Masthoff, E.D., Trompenaars, F.J., Hodiamont, P.Multisensory integration of emotional faces and voices in schizophrenics. Schizophr Res 2005;72(2–3):195203.
[10]Edwards, J., Pattison, P.E., Jackson, H.J., Wales, R.J.Facial affect and affective prosody recognition in first-episode schizophrenia. Schizophr Res 2001;48(2–3):235253.
[11]Ekman, P., Friesen, W.V.Pictures of facial affect. Palo Alto (CA): Consulting Psychologists Press; 1976.
[12]Elfenbein, H.A., Ambady, N.On the universality and cultural specificity of emotion recognition: a meta-analysis. Psychol Bull 2002;128(2):203235.
[13]Feinberg, T.E., Rifkin, A., Schaffer, C., Walker, E.Facial discrimination and emotional recognition in schizophrenia and affective disorders. Arch Gen Psychiatry 1986;43(3):276279.
[14]First, M.B., Spitzer, R.L., Gibbon, M., Williams, J.B.W.Structured clinical interview for DSM-IV-TR Axis I disorders. Patient ed. (SCID-I/P, 11/2002 revision) New York (NY): Biometrics Research Department; 2002.
[15]Friedman, J.I., Harvey, P.D., Coleman, T., Moriarty, P.J., Bowie, C., Parrella, M.et al.Six-year follow-up study of cognitive and functional status across the lifespan in schizophrenia: a comparison with Alzheimer's disease and normal aging. Am J Psychiatry 2001;158(9):14411448.
[16]Heaton, R.K.Wisconsin Card Sorting Test. Odessa (Fl): Psychological Assessment Resources; 1981.
[17]Heinrichs, R.W., Zakzanis, K.K.Neurocognitive deficits in schizophrenia: a quantitative review of the evidence. Neuropsychology 1998;12:426445.
[18]Jolley, S., Garety, P., Bebbington, P., Dunn, G., Freeman, D., Kuipers, E.et al.Attributional style in psychosis – the role of affect and belief type. Behav Res Ther 2006;44(11):15971607.
[19]Kaney, S., Bentall, R.P.Persecutory delusions and attributional study. Br J Med Psychol 1989;62:191198.
[20]Kay, S.R., Fiszbein, A., Opier, L.A.The Positive and Negative Syndrome Scale (PANSS) for schizophrenia. Schizophr Bull 1987;13:261276.
[21]Kerr, S.L., Neale, J.M.Emotion perception in schizophrenia: specific deficit or further evidence of generalized poor performance?. J Abnorm Psychol 1993;102(2):312318.
[22]Kohler, C.G., Bilker, W., Hagendoorn, M., Gur, R.E., Gur, R.C.Emotion recognition deficit in schizophrenia: association with symptomatology and cognition. Biol Psychiatry 2000;48(2):127136.
[23]Kohler, C.G., Martin, E.A.Emotional processing in schizophrenia. Cogn Neuropsychiatry 2006;11(3):250271.
[24]Kohler, C.G., Turner, T.H., Bilker, W.B., Brensinger, C.M., Siegel, S.J., Kanes, S.J.et al.Facial emotion recognition in schizophrenia: intensity effects and error pattern. Am J Psychiatry 2003;160(10):17681774.
[25]Kucharska-Pietura, K., David, A.S., Masiak, M., Phillips, M.L.Perception of facial and vocal affect by people with schizophrenia in early and late stages of illness. Br J Psychiatry 2005;187:523528.
[26]Mandal, M.K., Pandey, R., Prasad, A.B.Facial expressions of emotions and schizophrenia: a review. Schizophr Bull 1998;24(3):399412.
[27]Nelson, H.E., Wilson, J.National adult reading test manual. Windsor (CA): NFER-Nelson; 1991.
[28]Peer, J.E., Rothmann, T.L., Penrod, R.D., Penn, D.L., Spaulding, W.D.Social cognitive bias and neurocognitive deficit in paranoid symptoms: evidence for an interaction effect and changes during treatment. Schizophr Res 2004;71(2–3):463471.
[29]Premkumar, P., Kumari, V., Corr, P.J., Sharma, T.Frontal lobe volumes in schizophrenia: effects of stage and duration of illness. J Psychiatr Res 2006;40:627637.
[30]Russell, T.A., Reynaud, E., Kucharska-Pietura, K., Ecker, C., Benson, P.J., Zelaya, F.et al.Neural responses to dynamic expressions of fear in schizophrenia. Neuropsychologia 2007;45(1):107123.
[31]Salem, J.E., Kring, A.M., Kerr, S.L.More evidence for generalized poor performance in facial emotion perception in schizophrenia. J Abnorm Psychol 1996;105(3):480483.
[32]Schneider, F., Gur, R.C., Gur, R.E., Shtasel, D.L.Emotional processing in schizophrenia: neurobehavioral probes in relation to psychopathology. Schizophr Res 1995;17(1):6775.
[33]Schneider, F., Gur, R.C., Koch, K., Backes, V., Amunts, K., Shah, N.J.et al.Impairment in the specificity of emotion processing in schizophrenia. Am J Psychiatry 2006;163(3):442447.
[34]Sergi, M.J., Green, M.F.Social perception and early visual processing in schizophrenia. Schizophr Res 2003;59(2–3):233241.
[35]Silver, H., Goodman, C., Knoll, G., Isakov, V., Modai, I.Schizophrenia patients with a history of severe violence differ from nonviolent schizophrenia patients in perception of emotions but not cognitive function. J Clin Psychiatry 2005;66(3):300308.
[36]Silver, H., Shlomo, N., Turner, T., Gur, R.C.Perception of happy and sad facial expressions in chronic schizophrenia: evidence for two evaluative systems. Schizophr Res 2002;55(1–2):171177.
[37]Silver, H., Shlomo, N.Perception of facial emotions in chronic schizophrenia does not correlate with negative symptoms but correlates with cognitive and motor dysfunction. Schizophr Res 2001;52(3):265273.
[38]Smari, J., Stefansson, S., Thorgilsson, H.Paranoia, self-consciousness, and social cognition in schizophrenics. Cogn Ther Res 1994;18(4):387399.
[39]Toomey, R., Schuldberg, D., Corrigan, P., Green, M.F.Nonverbal social perception and symptomatology in schizophrenia. Schizophr Res 2002;53(1–2):8391.
[40]Williams, L.M., Das, P., Harris, A.W.F., Liddell, B.B., Brammer, M.J., Olivieri, G.et al.Dysregulation of arousal and amygdala–prefrontal systems in paranoid schizophrenia. Am J Psychiatry 2004;161(3):480489.
[41]Williams, L.M., Das, P., Liddell, B.J., Olivieri, G., Peduto, A.S., David, A.S.et al.Fronto-limbic and autonomic disjunctions to negative emotion distinguish schizophrenia subtypes. Psychiatry Res 2007;155(1):2944.
[42]Wolwer, W., Streit, M., Polzer, U., Gaebel, W.Facial affect recognition in the course of schizophrenia. Eur Arch Psychiatry Clin Neurosci 1996;246(3):165170.

Keywords

Misattribution bias of threat-related facial expressions is related to a longer duration of illness and poor executive function in schizophrenia and schizoaffective disorder

  • Preethi Premkumar (a1), Michael A. Cooke (a1), Dominic Fannon (a2), Emmanuelle Peters (a1), Tanja M. Michel (a3) (a4), Ingrid Aasen (a1), Robin M. Murray (a2), Elizabeth Kuipers (a1) and Veena Kumari (a1)...

Metrics

Altmetric attention score

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed.

Misattribution bias of threat-related facial expressions is related to a longer duration of illness and poor executive function in schizophrenia and schizoaffective disorder

  • Preethi Premkumar (a1), Michael A. Cooke (a1), Dominic Fannon (a2), Emmanuelle Peters (a1), Tanja M. Michel (a3) (a4), Ingrid Aasen (a1), Robin M. Murray (a2), Elizabeth Kuipers (a1) and Veena Kumari (a1)...
Submit a response

Comments

No Comments have been published for this article.

×

Reply to: Submit a response


Your details


Conflicting interests

Do you have any conflicting interests? *