The cardiovascular desease is the great reason for mortality of the patiens. The comorbidity with the depression have a great influence of the incidence, morbidity and mortality. Some live events make the depression efects worse for the patient who take cardio-surgery treatment.

is to find the importance of some life events to depression of the patients with cardio-surgery intervention.

In this study there was 30 patients, hospitalised at Cardiosugery Hospital Filip II, Skopje for cardio-surgery intervention (aorto-coronary by pass), 38–79 age, both male and female. These psychiatric instuments were used:Hamilton depression scale (HAMD), (17 itema scale with max score 52 and minimal score 0) and Scale for living stres factors of Holms and Rahe.

The average score of depression preoperation on HAMD scale is 16.77 ± 8.05, and the postoperation score were incresed to 21,25 and is high statistical significance (p < 0.01).The some events like death of member of the family, the illness, a big finansical changes significantly increace the depression (p < 0.01), but a newborn in the family, the holidays significantly decrese the depression on the participants (p < 0.05).

Multidisciplinary approach with the team of psyciatrists, psychologist of patient with cardiovascular desease make the despression efects small and the patients have good recovery.