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A family study of obsessive compulsive, eating and mood disorders

Published online by Cambridge University Press:  16 April 2020

L Pasquale ,
G Sciuto ,
S Cocchi ,
P Ronchi  and
L Bellodi
L Pasquale
Affiliation:
Department of Neuropsychiatries Sciences
G Sciuto
Affiliation:
Department of Neuropsychiatries Sciences
S Cocchi
Affiliation:
Department of Neuropsychiatries Sciences
P Ronchi
Affiliation:
Department of Neuropsychiatries Sciences
L Bellodi
Affiliation:
Divisione di Psichiatria 2, Cattedra di Psicopathologia, School of Medicine, University of Milan, S Raffaele Hospital, 29 via Prinetti, Milan20127, Italy
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Summary

We calculated Morbidity Risks (MR%) for the major psychiatric conditions in the families of three groups of patients, affected by Eating Disorders (ED; n = 41), Obsessive Compulsive Disorder (OCD; n = 70) and Mood Disorders (MD; n = 39). Our aim was to verify the hypothesis of a common familial pattern of aggregation. Familial risk of developing OCD was significantly increased in the families of OCD probands. Homotypic cases were also augmented in ED and MD families with respect to the rates of the general population, although without statistical significance in the crosswise comparisons. These results confirm the existence of a genetic susceptibility to the development of OCD.

Keywords

obsessive compulsive disordereating disordersmood disordersmorbidity riskgenetic epidemiology
Type
Original article
Information
European Psychiatry , Volume 9 , Issue 1 , 1994 , pp. 33 - 38
Copyright
Copyright © Elsevier, Paris 1994

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