The essential feature of Boderline Personality Disorder is pervasive pattern of instability of interpersonal relationships, self-image, affects and marked impulsivity. These individuals may show performance in school or work situations unstructured. Impulsivity exhibit is potentially harmful to themselves. They can play, make irresponsible spending, overeating, engage in unsafe sex and abusing psychoactive substances. They also have, recursively, self-mutilating behavior and threats of suicide.

The following case features a patient whose characteristics meet the diagnostic criteria for boderline personality, with positive family history of psychiatric illness and user of multiple drugs, particularly cocaine, marijuana and alcohol, who has been trated by the same professional team between 2011 and 2013, with an average of 2.3 psychiatric hospitalizations per year with the signs unchanged until the last year. The introduction of Aripiprazole caused the remission of some symptons and attenuating others, with significant improvement in quality of life, as the scope of complete abstinence from drug use and school progress.

Although only one case, the excellence of the results with Aripiprazole in mood stabilization and improvement of impulsive behaviors, especially in the cessation of compulsive use of drugs, makes our attention turns to this substance so that it remains subject of further studies.