Hostname: page-component-848d4c4894-4rdrl Total loading time: 0 Render date: 2024-06-23T02:05:36.697Z Has data issue: false hasContentIssue false

Central Nervous System Tumours in Adults with Intellectual Disability: a Case Series

Published online by Cambridge University Press:  15 April 2020

K. Courtenay
Affiliation:
Dept. Mental Health Sciences, UCL, London, United Kingdom
N. Eady
Affiliation:
Dept. Mental Health Sciences, UCL, London, United Kingdom
S. Jaydeokar
Affiliation:
Haringey Learning Disability Partnership, Barnet Enfield Haringey MH NHS Trust, London, United Kingdom

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
Aim

To present a case series of de-novo central nervous system (CNS) tumours in adults with intellectual disabilities (ID).

Method

Three cases of de-novo brain tumours in adults with (ID) were identified. The casenotes were reviewed and compared with the current evidence base of CNS tumours.

Result

Three women aged 44-50 were identified with CNS tumours. Two cases with mild ID and one with severe ID. The first presented with depression. Cranial imaging was unremarkable. She experienced a seizure due to a benign meningioma. The woman had Bipolar Affective Disorder and diabetes mellitus presented with Parkinson’s Disease. Intracranial scanning revealed a diencepahlic tumour. The third woman had dysphagia and vertigo. Imaging identified two meningiomas.

Conclusions

The prevalence of primary CNS tumours in people with ID is uncertain. The presentation and histopathology of the three tumours varies. In all three, diagnosis was delayed perhaps due to diagnostic overshadowing. Establishing the characteristics of primary CNS tumours in adults with ID and their presentation should progress our knowledge. Further epidemiological research is required to establish the prevalence of tumours in adults with ID. The clinical management of CNS tumours in adults with ID must include exploration of the best interests of the person and the implications for end-of-life care. The authors acknowledge the limitations of a case series and recommend a national cohort as an epidemiological sample.

Type
Article: 1475
Copyright
Copyright © European Psychiatric Association 2015
Submit a response

Comments

No Comments have been published for this article.