Hostname: page-component-848d4c4894-jbqgn Total loading time: 0 Render date: 2024-06-23T00:39:54.044Z Has data issue: false hasContentIssue false
  • English
  • Français

The association of the metabolic profile in diabetes mellitus type 2 patients with obsessive compulsive disorder and depression: New insights

Published online by Cambridge University Press:  16 April 2020

K. Kontoangelos ,
A. Raptis ,
C.C. Papageorgiou ,
G.N. Papadimitriou ,
A.D. Rabavilas ,
G. Dimitriadis  and
S.A. Raptis
K. Kontoangelos
Affiliation:
1st Department of Psychiatry,Eginition Hospital, Athens University Medical School, Athens, Greece
A. Raptis
Affiliation:
2nd Department of Internal Medicine -Propaedeutic-Research Institute and Diabetes Center, Athens University Medical School -Attikon Hospital, Athens, Greece
C.C. Papageorgiou
Affiliation:
1st Department of Psychiatry,Eginition Hospital, Athens University Medical School, Athens, Greece
G.N. Papadimitriou
Affiliation:
1st Department of Psychiatry,Eginition Hospital, Athens University Medical School, Athens, Greece
A.D. Rabavilas
Affiliation:
University Mental Health Research Institute, Athens, Greece
G. Dimitriadis
Affiliation:
2nd Department of Internal Medicine -Propaedeutic-Research Institute and Diabetes Center, Athens University Medical School -Attikon Hospital, Athens, Greece
S.A. Raptis
Affiliation:
2nd Department of Internal Medicine -Propaedeutic-Research Institute and Diabetes Center, Athens University Medical School -Attikon Hospital, Athens, Greece Hellenic National Center for Research, Prevention and Treatment of Diabetes Mellitus and Its Complications (H.N.D.C), Athens, Greece

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
Introduction

The high comorbidity of depression in patients with diabetes mellitus type 2 has been established.

Objectives

The association between Obsessive Compulsive Disorder (OCD) and diabetes mellitus type 2 is poorly understood.

Aims

The aim of the present study was to assess the degree in which diabetes mellitus type 2 is accompanied by OCD.

Method

131 diabetic patients, 55 female and 76 male were randomly enrolled and during the first assessment was administered in all participants the Zung Self Rating Scale (ZUNG) and the Maudsley O-C Inventory Questionnaire (MOCI). After one year, while an intensive effort to improve the patients’ metabolic profile was performed, the diabetic patients that were initially uncontrolled (n = 31) were re-evaluated by the same psychometric tools. From those 31 patients 10 had managed to control their metabolic profile.

Results

MOCI and the sub-scale of slowness are statistically related with the diabetic profile (controlled-uncontrolled), with uncontrolled patients scoring significantly higher on the overall MOCI score and the factor of slowness of MOCI scale (p = 0.028). Regarding the association between the values of Glycosylated Haemoglobin (HbA1c) and the scores of MOCI it was found that they were significantly positively correlated in overall scores (p = 0,028) and in the subscale of slowness (p = 0,028). The analysis revealed a positive association between depression (p = 0.004) and obsessive compulsive disorder symptomatology (p < 0.001) and thepatient’s metabolic profile.

Conclusions

Diabetes mellitus type 2 is associated with obsessive compulsive disorder symptomatology and depression. Improvements in glycaemic control were found to decrease the severity of the symptoms.

Type
P02-277
Information
European Psychiatry , Volume 26 , Issue S2: Abstracts of the 19th European Congress of Psychiatry , March 2011 , pp. 873
Copyright
Copyright © European Psychiatric Association 2011
Submit a response

Comments

No Comments have been published for this article.