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Association between flupenthixol treatment and emergence of manic symptoms

Published online by Cambridge University Press:  16 April 2020

D. Becker ,
Y. Grinberg ,
A. Weizman  and
R. Mester
D. Becker*
Affiliation:
Ness-Ziona Mental Health Center, Ness-Ziona, P.O. Box 1, Ness-Ziona74450, Israel
Y. Grinberg
Affiliation:
Ness-Ziona Mental Health Center, Ness-Ziona, P.O. Box 1, Ness-Ziona74450, Israel
A. Weizman
Affiliation:
Geha Psychiatric Hospital, Rabin Medical Center, Petah Tiqva and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
R. Mester
Affiliation:
Ness-Ziona Mental Health Center, Ness-Ziona, P.O. Box 1, Ness-Ziona74450, Israel
*
*Corresponding author.
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Summary

Background.

Flupenthixol is an antipsychotic drug with known mood-elevating properties. Its propensity to induce manic symptoms has not been investigated.

Methods and results.

We describe six patients, four with schizophrenia and two with bipolar disorder, in whom flupenthixol treatment was associated with emergence of manic symptoms.

Conclusions.

Patients treated with flupenthixol should be carefully monitored for the emergence of manic symptoms.

Keywords

FlupenthixolManiaAntipsychotic
Type
Original article
Information
European Psychiatry , Volume 17 , Issue 6 , October 2002 , pp. 349 - 352
Copyright
Copyright © Éditions scientifiques et médicales Elsevier SAS 2002

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