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Alcohol and Sedative Use Disorders in the Lebanese Population: Role of Sleep and Psychiatric Factors

Published online by Cambridge University Press:  27 August 2024

K. Chamoun ,
N. Wehbe ,
P. Salameh ,
H. Sacre ,
M. Atallah ,
J. Mouawad ,
L. Rabbaa ,
B. Megarbane  and
A. Hajj
K. Chamoun
Affiliation:
1Laboratoire de Pharmacologie, Pharmacie Clinique et Contrôle de Qualité des Médicaments 2Faculty of Pharmacy, Saint Joseph University, Beirut, Lebanon 3Inserm, UMR-S1144, Université Paris Cité, Paris, France
N. Wehbe
Affiliation:
2Faculty of Pharmacy, Saint Joseph University, Beirut, Lebanon
P. Salameh
Affiliation:
4INSPECT-LB (Institut National de Santé Publique, d’Épidémiologie Clinique et de Toxicologie-Liban), Beirut 5School of Medicine, Lebanese American University, Byblos, Lebanon 6Department of Primary Care and Population Health, University of Nicosia Medical School, Nicosia, Cyprus 7Faculty of Pharmacy, Lebanese University, Hadat, Lebanon
H. Sacre
Affiliation:
4INSPECT-LB (Institut National de Santé Publique, d’Épidémiologie Clinique et de Toxicologie-Liban), Beirut
M. Atallah
Affiliation:
2Faculty of Pharmacy, Saint Joseph University, Beirut, Lebanon
J. Mouawad
Affiliation:
2Faculty of Pharmacy, Saint Joseph University, Beirut, Lebanon
L. Rabbaa
Affiliation:
1Laboratoire de Pharmacologie, Pharmacie Clinique et Contrôle de Qualité des Médicaments 2Faculty of Pharmacy, Saint Joseph University, Beirut, Lebanon
B. Megarbane
Affiliation:
3Inserm, UMR-S1144, Université Paris Cité, Paris, France
A. Hajj*
Affiliation:
1Laboratoire de Pharmacologie, Pharmacie Clinique et Contrôle de Qualité des Médicaments 4INSPECT-LB (Institut National de Santé Publique, d’Épidémiologie Clinique et de Toxicologie-Liban), Beirut 8Faculty of Pharmacy, Université Laval 9Oncology Division, CHU de Québec- Université Laval Research Center, Quebec, Canada
*
*Corresponding author.

Abstract

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Introduction

Alcohol and sedative substance use disorders are escalating global public health challenges. Lebanon has grappled with multiple crises, including economic, healthcare, and social issues.

Objectives

This study aimed to assess the correlates of the alcohol and sedative substance use risk scores with sociodemographic and clinical factors, including sleep disorders, chronotype, anxiety, and depression.

Methods

A cross-sectional study was conducted among the Lebanese population using several validated scales to assess the risk of alcohol and sedative substance use, including the Alcohol, Smoking, and Substance Involvement Screening Test (ASSIST). Other tools evaluated chronotype, sleep, and mood disturbances. Bivariate and multivariable analyses were then performed, taking the alcohol and sedative scores as dependent variables.

Results

A total of 646 participants were included. Multivariate analysis revealed positive and significant correlations between higher ASSIST-alcohol scores and personal history of alcohol abuse (B=4.61), family history of prescription substance abuse (B=1.763), psychiatric disorders (B=2.898), and worse Insomnia Severity Index scores (Beta=0.14). Conversely, ASSIST-alcohol scores negatively correlated with weight (B= -0.39) and morning chronotype (B=-0.084). Positive correlations were identified between higher ASSIST-alcohol scores and personal history of illicit substance abuse (B=2.834), prescription substance abuse (B=2.252), sleep quality (B=0.130), and sleep severity (B=0.082), while negatively correlating with cigarette smoking (B=-0.038).

Conclusions

This study elucidates the role of several predisposing factors to alcohol and sedative use disorders in Lebanon, including history of substance abuse, psychiatric disorders, sleep disorders, and chronotype. These findings advocate, in particular, for the integration of sleep disorder assessment and management into addiction rehabilitation programs.

Disclosure of Interest

None Declared

Type
Abstract
Information
European Psychiatry , Volume 67 , Special Issue S1: Abstracts of the 32nd European Congress of Psychiatry , April 2024 , pp. S131 - S132
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2024. Published by Cambridge University Press on behalf of European Psychiatric Association
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