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Akathisia: Old challenge for new antipsychotic agents

Published online by Cambridge University Press:  16 April 2020

M. Mihanovic
Affiliation:
Female Department for Prolonged Treatment, Psychiatric Hospital
D. Bodor
Affiliation:
Department for Psychotherapy and Sociotherapy of Neurotic and Psychotic Disorders, Psychiatric Hospital
P. Filakovic
Affiliation:
Psychiatric Clinic, Clinical Hospital Osijek, Osijek, Croatia
M. Grah
Affiliation:
Department for Psychotherapy and Sociotherapy of Neurotic and Psychotic Disorders, Psychiatric Hospital
S. Devčic
Affiliation:
Female Department for Prolonged Treatment, Psychiatric Hospital
D. Sago
Affiliation:
Male Department for Acute Treatment, Psychiatric Hospital
I. Sain
Affiliation:
Male Department for Acute Treatment, Psychiatric Hospital

Abstract

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Akathisia is well known extrapyramidal side-effect of conventional antipsychotic agents, which has been almost forgotten when new antipsychotics was developed. However, the uses of new antipsychotics have shown that it was anticipatory optimism, because new antipsychotics can cause akathisia as well as conventional. Since clinical presentation of akathisia may include psychiatry symptoms such as anxiety, mental unease, disforia etc. it can easily be misinterpreted as worsening of primary psychiatric illness especially schizophrenia or bipolar disorder which can cause wrong therapeutic intervention. It is very important to recognize akathisia in timely manner because its consequences especially high suicidal risk, can be fatal. Purpose of this work is to remind us on this, for patent very unpleasant and potentially dangerous side-effect, which was almost forgotten after beginning of therapeutic use of new antipsychotics. In this article we presented patient with schizophrenia who developed risperidon induced akathisia with suicidal pulsions. After reducing the dose of risperidon and implementation of clozapine patient's clinical condition was much improved.

Type
Poster Session 1: Antipsychotic Medications
Copyright
Copyright © European Psychiatric Association 2007
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