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A roadmap to disentangle the molecular etiology of schizophrenia

Published online by Cambridge University Press:  16 April 2020

Peter Falkai ,
Owen Mike ,
Myin-Germeys Inez ,
Harrison Paul ,
Bilkei-Gorzo Andras ,
Frangou Sophia  and
MEOS Consortium
Peter Falkai*
Affiliation:
Department of Psychiatry and Psychotherapy, University of Goettingen, Von-Siebold-Strasse 5, 37075Goettingen, Germany
Owen Mike
Affiliation:
Department of Psychological Medicine, School of Medicine, Cardiff University, Henry Wellcome Building, Heath Park, CardiffCF14 4XN, UK
Myin-Germeys Inez
Affiliation:
Deptment of Psychiatry and Neuropsychology, Maastricht University, PO BOX 616 (location DOT10), 6200MD Maastricht, The Netherlands
Harrison Paul
Affiliation:
Neurosciences Building, University Department of Psychiatry Warneford Hospital, OxfordOX3 7JX, UK
Bilkei-Gorzo Andras
Affiliation:
Department of Psychiatry, University of Bonn, Sigmund-Freud-Street 25, 53127Bonn, Germany
Frangou Sophia
Affiliation:
Section of Neurobiology of Psychosis, Institute of Psychiatry, De Crespigny Park, LondonSE5 8AF, UK
*
∗Corresponding author. Tel.: +49 (0) 551 39 6601; fax: +49 (0) 551 39 9337. E-mail address: pfalkai@gwdg.de (P. Falkai).
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Abstract

Schizophrenia is a severe mental disorder striking mainly young adults and leading to life-long disability in a substantial portion of the sufferers. On the other hand, substantial knowledge about its etiology and pathogenesis is still lacking. Therefore the European Science Foundation (ESF) sponsored a meeting of a panel of European experts on schizophrenia research to discuss the state of art and future perspectives of key topics in this area. The fields covered genetics, epidemiology, animal models, molecular neuropathology and imaging. This was a first step to establish a network of European groups dedicated to Schizophrenia research. The coming calls of the frame work program will be used to strengthen this network in order to achieve substantial progress in understanding and treating this devastating illness.

Keywords

Imaging, molecular neuropathologyImaging and bipolar disordersAnimal modelsGene–environment interactionMolecular neuropathology, function of susceptibility genesImagingGenetic of psychiatric illnessesGenetics, function of susceptibility genesImaging and early recognitionEpidemiologyGeneticsDevelopment of pharmacotropic agents from target proteinsLarge-scale clinical studies on schizophrenia
Type
Original article
Information
European Psychiatry , Volume 23 , Issue 4 , June 2008 , pp. 224 - 232
Copyright
Copyright © European Psychiatric Association 2008

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