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Assessing health-related quality of life in patients suffering from schizophrenia: a comparison of instruments

Published online by Cambridge University Press:  16 April 2020

Gilles Reine*
Affiliation:
Department of Psychiatry 83 G04, Pavillon Arthur Rimbaud, La Seyne sur Mer hospital, BP 1412, 83056Toulon cedex, France
Marie-Claude Simeoni
Affiliation:
Self-Perceived Health Assessment Research Unit, Public Health Department, School of Medicine, Marseille, France
Pascal Auquier
Affiliation:
Self-Perceived Health Assessment Research Unit, Public Health Department, School of Medicine, Marseille, France
Anderson Loundou
Affiliation:
Self-Perceived Health Assessment Research Unit, Public Health Department, School of Medicine, Marseille, France
Valérie Aghababian
Affiliation:
Psychology Research Unit PSYCLE, School of Psychology, Aix-en-Provence, France
Christophe Lancon
Affiliation:
Department of Psychiatry, Sainte Marguerite University Hospital, Marseille, France
*
*Corresponding author. Tel.: +33 4 94 11 30 85; fax: +33 4 94 11 30 54.E-mail address:Gilles.Reine@ch-toulon.fr (G. Reine).
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Abstract

Objective

To compare three different kinds of health-related quality of life (HRQL) questionnaires available for use in patients suffering from schizophrenia: the SF-36 (a generic instrument), the QoLI (an instrument designed to a broad range of mental illnesses), the S-QoL (a questionnaire specific to schizophrenic patients), in terms of external validity and sensitivity to change.

Methods

Two hundred and five patients were included at D0 and one-third retested at D30. Socio-demographic data and clinical history were recorded, clinical evaluation comprised psychotic symptoms (PANSS), depression (Calgary depression scale for schizophrenia), global functioning (GAF), clinical severity (CGI), and extrapyramidal symptoms (ESRS). HRQL was assessed using the SF-36, the QoLI and the S-QoL.

Results

A better agreement is observed between the SF-36 and the S-QoL than between the QoLI and the two other instruments. S-QoL and SF-36 are more strongly correlated with clinical status than QoLI. Compared to the SF-36 and the QoLI, the S-QoL better discriminates patients with comorbidity from others. The S-QoL shows better responsiveness than the QoLI and the SF-36.

Conclusion

For descriptive purpose, either generic tools like SF-36 or specific ones should be used, whereas when aiming at evaluating health treatment and care for schizophrenic patients, specific instruments like the S-QoL should be favoured.

Type
Scales and Measurement of Psychopathology
Copyright
Copyright © Elsevier SAS 2005

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References

Addington, D., Addington, J., Maticka-Tyndale, E.Assessing depression in schizophrenia: the Calgary Depression Scale. Br. J. Psychiatry 1993;163:3944.CrossRefGoogle Scholar
American Psychiatric Association Diagnostic and statistical manual of mental disorders, 4th ed Washington, DC:APA;1994.Google Scholar
Auquier, P., Simeoni, M.C., Sapin, C., et al.Development and validation of a patient based health-related quality of life questionnaire in schizophrenia: the S-QoL. Schizophr. Res. 2003;63:137149.CrossRefGoogle ScholarPubMed
Bengtsson-Tops, A., Hansson, L.Quantitative and qualitative aspects of the social network in schizophrenic patients living in the community. Relationships to sociodemographic characteristics and clinical factors and subjective quality of life. Int. J. Soc. Psychiatry 2001;47:6777.CrossRefGoogle Scholar
Bernard, D., Lançon, C., Auquier, P., Reine, G., Addington, D.Calgary Depression Scale for Schizophrenia: a study of the validity of a French language version in a population of schizophrenic patients. Acta. Psychiatr. Scand. 1998;97:3641.CrossRefGoogle Scholar
Bow-Thomas, C.C., Velligan, D.I., Miller, A.L., Olsen, J.Predicting quality of life from symptomatology in schizophrenia at exacerbation and stabilization. Psychiatry Res. 1999;86:131142.CrossRefGoogle ScholarPubMed
Brekke, J.S., Kohrt, B., Green, M.F.Neuropsychological functioning as a moderator of the relationship between psychosocial functioning and the subjective experience of self and life schizophrenia. Schizophr. Bull. 2001;27:697708.CrossRefGoogle Scholar
Browne, S., Roe, M., Lane, A., et al.Quality of life in schizophrenia: Relationship to sociodemographic factors, symptomology, and tardive dyskinesia. Acta Psychiatr. Scand. 1996;94:118124.CrossRefGoogle Scholar
Chouinard, G., Ross-Chouinard, A., Annabale, L., Jones, B.D.The extrapyramidal symptom rating scale. Can. J. Neurol. Sci. 1980;7:233.Google Scholar
Cramer, J.A., Rosenheck, R., Xu, W., Henderson, W., Thomas, J., Charney, D.Detecting improvement in quality of life and symptomatology in schizophrenia. Schizophr. Bull. 2001;27:227234.CrossRefGoogle Scholar
Cramer, J.A., Rosenheck, R., Xu, W., Thomas, J., Henderson, W., Charney, D.Quality of life in schizophrenia: a comparison of instruments. Schizophr. Bull. 2000;26:659666.CrossRefGoogle ScholarPubMed
Delahanty, J., Ram, R., Postrado, L., Balis, T., Green-Paden, L., Dixon, L.Differences in rates of depression in schizophrenia by race. Schizophr. Bull. 2001;27:2938.CrossRefGoogle ScholarPubMed
Dickerson, F.B., Ringel, N.B., Parente, F.Subjective quality of life in out-patients with schizophrenia : clinical and utilization correlates. Acta Psychiatr. Scand. 1998;98:124127.CrossRefGoogle ScholarPubMed
Endicott, J., Spitzer, R., Fleiss, J.The Global Assessment Scale: a procedure for measuring overall severity of psychiatric disturbance. Arch. Gen. Psychiatry 1976;33:766771.CrossRefGoogle ScholarPubMed
Gaite, L., Vazquez-Barquero, J.L., Borra, C., et al.Quality of Life in patients with schizophrenia in five European countries : the EPSILON study. Acta Psychiatr. Scand. 2002;105:283292.CrossRefGoogle ScholarPubMed
Heinrichs, D.W., Hanlon, T.E., Carpenter, W.T.The quality of life scale: an instrument for rating the schizophrenic deficit syndrome. Schizoph Bull 1984;10:388398.CrossRefGoogle ScholarPubMed
Huppert, J.D., Weiss, K.A., Lim, R., Pratt, S., Smith, T.E.Quality of life in schizophrenia: contributions of anxiety and depression. Schizophr. Res. 2001;51:171180.CrossRefGoogle ScholarPubMed
Jin, H., Zisook, S., Palmer, B.W., Patterson, T.L., Heaton, R.K., Jeste, D.V.Association of depressive symptoms with worse functioning in schizophrenia: a study in older outpatients. J. Clin. Psychiatry 2001;62:797803.CrossRefGoogle ScholarPubMed
Kay, S.R., Opler, L.A., Lindenmayer, J.P.The Positive and Negative Syndrome Scale (PANSS): rationale and standardization. Br. J. Psychiatry 1989;155:5965.CrossRefGoogle Scholar
Lançon, C., Auquier, P., Launois, R., et al.Évaluation de la qualité de vie des patients schizophrènes: validation de la version courte de la QoLI. Encephale 2000;26:1116.Google Scholar
Lançon, C., Auquier, P., Nayt, G., Reine, G.Stability of the five-factor structure of the Positive and Negative Syndrome Scale (PANSS). Schizophr. Res. 2000;42:231239.CrossRefGoogle Scholar
Lehman, A.F., Burns, B.Severe mental illness in the community. In: Spilker, B.Quality of life assessment in clinical trials New York: Plenum Press; 1990.p. 357366.Google Scholar
Lehman, A.F.Well-being of chronic mental patients: assessing their quality of life. Arch. Gen. Psychiatry 1983;40:369373.CrossRefGoogle Scholar
Leplege, A., Ecosse, E., Verdier, A., Perneger, T.V.The French SF-36 health survey: translation, cultural adaptation and preliminary psychometric evaluation. J. Clin. Epidemiol. 1998;11:10131024.CrossRefGoogle Scholar
Loi n° 88-1138 relative à la protection des personnes qui se prêtent à des recherches biomédicales du 20.12.1988. Paris: Journal Officiel, 22 Dec 1988.Google Scholar
Norman, R.M., Malla, A.K., Mc Lean, T., et al.The relationships of symptoms and level of functioning in schizophrenia to general wellbeing and the Quality of Life Scale. Acta Psychiatr. Scand. 2000;102:303309.CrossRefGoogle Scholar
Packer, S., Husted, J., Cohen, S., Tomlinson, G.Psychopathology and quality of life in schizophrenia. J. Psychiatr. Neurosci. 1997;22:231234.Google Scholar
Patrick, D., Chiang, Y.P.Measurement of health outcome in treatment effectiveness evaluations: conceptual and methodological challenges. Med. Care 2000;9:1425.Google Scholar
Reine, G., Lançon, C., Di Tucci, S., Sapin, C., Auquier, P.Depression and subjective quality of life in chronic phase schizophrenic patients. Acta Psychiatr. Scand. 2003;108:297303.CrossRefGoogle ScholarPubMed
Ritsner, M., Kurs, R., Gibel, A., Hirschmann, S., Shinkarendko, E., Ratner, Y.Predictors of quality of life in major psychoses: a naturalistic follow-up study. J. Clin. Psychiatry 2003;64:308315.CrossRefGoogle ScholarPubMed
Steward, A.L., Ware, J.Measuring function and well-being Durham, NC: Duke University Press; 1992.Google Scholar
Tek, C., Kirkpatrick, B., Buchanan, R.W.A five year follow-up study of deficit and nondeficit schizophrenia. Schizophr. Res. 2001;49:253260.CrossRefGoogle ScholarPubMed
Tollefson, G.D., Andersen, M.S.Should we consider mood disturbance in schizophrenia as an important determinant of quality of life? J. Clin. Psychiatry 1999;60:2329.Google ScholarPubMed
Ware, J.E., Sherbourne, C.D.The MOS 36-Item Short-Form health survey (SF-36) : I. conceptual framework and item selection. Med. Care 1992;30:473483.CrossRefGoogle ScholarPubMed
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