Recently, due to social, ecological and endoecological factors, pathomorphism in narcological pathological conditions has determined formation of a new scientific and applied concept - integrative narcology. Item phasized new strategies in improvement of addictology medical programs based on international experience extrapolation.

Principal tasks of integrative narcology centres include reduction of negative consequences resulted from psychoactive substances long-term intake, lowering the risk of chronic comorbidity, decreasing the harm caused by narcotization and polypragmasy at uncoordinated isolated services.

Integrative narcology aims at a complex expert approach to treatment of combined postintoxication somatoneurological disorders in one drug- and alcohol-addict.

Integrative medicine main concept is bound together by the evidence-based medicine methods, emergency urgent and intensive therapy aids with drug-free, medication and rehabilitation-restorative programs. Statement of the mentioned problems is extremely important for the health of a patient and society in general.

The first pilot trial in Ukraine of the patterns for integrated complex therapeutic aid were based on the cohorts of the HIV- infected opioid addicts, patients with comorbidity (tuberculosis, chroniosepsis, hepatites, cardiomyopathy, epilepsy, depression). Activity of the centres includes methods with detoxication, anticraving, immunomodulation therapeutic effects connecting with different medical subjects: nanotechnological modifications of membrane plasmapheresis, laser therapy, hyperbaric oxygenation, ozone therapeutics, acupuncture, psychotherapy, transcranial electrostimulation methods, sorption detoxication, craniocerebralhypothermy, extremal cryopuncture, general ultralow dosage hypothermy, etc.