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Dimensions of adversity in association with adolescents’ depression symptoms: Distinct moderating roles of cognitive and autonomic function

Published online by Cambridge University Press:  17 December 2019

Rachel A. Vaughn-Coaxum Open the ORCID record for Rachel A. Vaughn-Coaxum [Opens in a new window] ,
Neha Dhawan ,
Margaret A. Sheridan ,
Mackenzie J. Hart  and
John R. Weisz
Rachel A. Vaughn-Coaxum*
Affiliation:
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA Department of Psychology, Harvard University, Cambridge, MA, USA
Neha Dhawan
Affiliation:
Department of Psychology, Harvard University, Cambridge, MA, USA
Margaret A. Sheridan
Affiliation:
Department of Psychology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
Mackenzie J. Hart
Affiliation:
Department of Psychology, University of South Carolina, Columbia, SC, USA
John R. Weisz
Affiliation:
Department of Psychology, Harvard University, Cambridge, MA, USA
*
Corresponding Author: Rachel A. Vaughn-Coaxum, 557 Bellefield Towers, 100 N. Bellefield Ave., Pittsburgh, PA15203, USA. E-mail: coauxmra@upmc.edu.
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Abstract

Exposure to adverse events is prevalent among youths and robustly associated with risk for depression, particularly during adolescence. The Dimensional Model of Adversity and Psychopathology (DMAP) distinguishes between adverse events that expose youths to deprivation versus threat, positing unique mechanisms of risk (cognitive functioning deficits for deprivation, and altered fear and emotion learning for threat) that may require different approaches to intervention. We examined whether deprivation and threat were distinctly associated with behavioral measures of cognitive processes and autonomic nervous system function in relation to depression symptom severity in a community sample of early adolescents (n = 117; mean age 12.73 years; 54.7% male). Consistent with DMAP, associations between threat and depression symptoms, and between economic deprivation and depression symptoms, were distinctly moderated by physiological and cognitive functions, respectively, at baseline but not follow-up. Under conditions of greater cognitive inhibition, less exposure to deprivation was associated with lower symptom severity. Under conditions of blunted resting-state autonomic response (electrodermal activity and respiratory sinus arrhythmia), greater exposure to threat was associated with higher symptom severity. Our findings support the view that understanding risk for youth depression requires parsing adversity: examining distinct roles played by deprivation and threat, and the associated cognitive and biological processes.

Keywords

childhood adversitydepressionthreatdeprivationpsychophysiology
Type
Regular Articles
Information
Development and Psychopathology , Volume 32 , Issue 3 , August 2020 , pp. 817 - 830
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Copyright
Copyright © Cambridge University Press 2019

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