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In the eye of the beholder: Perceptions of neighborhood adversity and psychotic experiences in adolescence

Published online by Cambridge University Press:  22 November 2017

Joanne B. Newbury
Affiliation:
King's College London
Louise Arseneault
Affiliation:
King's College London
Avshalom Caspi
Affiliation:
King's College London Duke University
Terrie E. Moffitt
Affiliation:
King's College London Duke University
Candice L. Odgers
Affiliation:
Duke University
Jessie R. Baldwin
Affiliation:
King's College London
Helena M. S. Zavos
Affiliation:
King's College London
Helen L. Fisher*
Affiliation:
King's College London
*
Address correspondence and reprint requests to: Helen L. Fisher, MRC SGDP Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, 16 De Crespigny Park, London SE5 8AF, UK; E-mail: helen.2.fisher@kcl.ac.uk.

Abstract

Adolescent psychotic experiences increase risk for schizophrenia and other severe psychopathology in adulthood. Converging evidence implicates urban and adverse neighborhood conditions in the etiology of adolescent psychotic experiences, but the role of young people's personal perceptions of disorder (i.e., physical and social signs of threat) in their neighborhood is unknown. This was examined using data from the Environmental Risk Longitudinal Twin Study, a nationally representative birth cohort of 2,232 British twins. Participants were interviewed at age 18 about psychotic phenomena and perceptions of disorder in the neighborhood. Multilevel, longitudinal, and genetically sensitive analyses investigated the association between perceptions of neighborhood disorder and adolescent psychotic experiences. Adolescents who perceived higher levels of neighborhood disorder were significantly more likely to have psychotic experiences, even after accounting for objectively/independently measured levels of crime and disorder, neighborhood- and family-level socioeconomic status, family psychiatric history, adolescent substance and mood problems, and childhood psychotic symptoms: odds ratio = 1.62, 95% confidence interval [1.27, 2.05], p < .001. The phenotypic overlap between adolescent psychotic experiences and perceptions of neighborhood disorder was explained by overlapping common environmental influences, rC = .88, 95% confidence interval [0.26, 1.00]. Findings suggest that early psychological interventions to prevent adolescent psychotic experiences should explore the role of young people's (potentially modifiable) perceptions of threatening neighborhood conditions.

Type
Special Issue Articles
Copyright
Copyright © Cambridge University Press 2017 

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Footnotes

We are grateful to the study mothers and fathers, the twins, and the twins’ teachers for their participation. Our thanks to members of the E-Risk team for their dedication, hard work, and insights, and to CACI Inc. for use of their consumer lifestyle databases. We also thank Emma Hedman for geocoding assistance. The Environmental Risk (E-Risk) Longitudinal Twin Study is funded by the Medical Research Council (G1002190). Additional support was provided by National Institute of Child Health and Human Development (HD077482); the British Academy (SQ140024); and the Jacobs Foundation. Support was also provided through Multidisciplinary Studentships from the Economic and Social Research Council (ESRC; to J.B.N. and J.R.B.); a Mental Health Leadership Fellowship for the UK ESRC (to L.A.); MQ Fellows Award MQ14F40 (to H.L.F.); and a Jacobs Foundation and Canadian Institute for Advanced Research Fellowship (to C.L.O.). The last two authors are joint senior authors.

References

American Psychiatric Association. (1994). Diagnostic and statistical manual of mental disorders (4th ed.). Washington, DC: Author.Google Scholar
An, S. K., Kang, J. I., Park, J. Y., Kim, K. R., Lee, S. Y., & Lee, E. (2010). Attribution bias in ultra-high risk for psychosis and first-episode schizophrenia. Schizophrenia Research, 118, 5461.CrossRefGoogle ScholarPubMed
Appiah-Kusi, E., Fisher, H. L., Petros, N., Wilson, R., Mondelli, V., Garety, P., … Bhattacharyya, S. (2017). Do cognitive schema mediate the association between childhood trauma and being at ultra-high risk for psychosis? Journal of Psychiatric Research, 88, 8996.Google Scholar
Bhavsar, V., Boydell, J., Murray, R., & Power, P. (2014). Identifying aspects of neighbourhood deprivation associated with increased incidence of schizophrenia. Schizophrenia Research, 156, 115121.Google Scholar
Breen, R., Karlson, K. B., & Holm, A. (2013). Total, direct, and indirect effects in logit and probit models. Sociological Methods & Research, 42, 164191.Google Scholar
Brown, J., Berenson, K., & Cohen, P. (2005). Documented and self-reported child abuse and adult pain in a community sample. Clinical Journal of Pain, 21, 374377.CrossRefGoogle Scholar
CACI Information Services. (2006). ACORN user guide. London: Author.Google Scholar
Caspi, A., Taylor, A., Moffitt, T. E., & Plomin, R. (2000). Neighborhood deprivation affects children's mental health: Environmental risks identified in a genetic design. Psychological Science, 11, 338342.Google Scholar
Collip, D., Nicolson, N., Lardinois, M., Lataster, T., van Os, J., & Myin-Germeys, I. (2011). Daily cortisol, stress reactivity and psychotic experiences in individuals at above average genetic risk for psychosis. Psychological Medicine, 41, 23052315.CrossRefGoogle ScholarPubMed
Dhossche, D., Ferdinand, R., van der Ende, J., Hofstra, M., & Verhulst, F. (2002). Diagnostic outcome of self-reported hallucinations in a community sample of adolescents. Psychological Medicine, 32, 619627.CrossRefGoogle Scholar
Dye, C. (2008). Health and urban living. Science, 319, 766769.Google Scholar
Ellett, L., Freeman, D., & Garety, P. A. (2008). The psychological effect of an urban environment on individuals with persecutory delusions: The Camberwell walk study. Schizophrenia Research, 99, 7784.CrossRefGoogle ScholarPubMed
Fisher, H. L., Caspi, A., Poulton, R., Meier, M. H., Houts, R., Harrington, H., … Moffitt, T. E. (2013). Specificity of childhood psychotic symptoms for predicting schizophrenia by 38 years of age: A birth cohort study. Psychological Medicine, 43, 20772086.CrossRefGoogle ScholarPubMed
Fowler, D., Freeman, D., Smith, B., Kuipers, E., Bebbington, P., Bashforth, H., … Dunn, G. (2006). The Brief Core Schema Scales (BCSS): Psychometric properties and associations with paranoia and grandiosity in non-clinical and psychosis samples. Psychological Medicine, 36, 749759.CrossRefGoogle ScholarPubMed
Freeman, D. (2016). Persecutory delusions: A cognitive perspective on understanding and treatment. Lancet Psychiatry, 3, 685692.CrossRefGoogle ScholarPubMed
Freeman, D., Emsley, R., Dunn, G., Fowler, D., Bebbington, P., Kuipers, E., … Garety, P. (2014). The stress of the street for patients with persecutory delusions: A test of the symptomatic and psychological effects of going outside into a busy urban area. Schizophrenia Bulletin, 41, 971979.CrossRefGoogle ScholarPubMed
Freeman, D., Garety, P. A., Kuipers, E., Fowler, D., & Bebbington, P. E. (2002). A cognitive model of persecutory delusions. British Journal of Clinical Psychology, 41, 331347.CrossRefGoogle ScholarPubMed
Freeman, D., Waller, H., Harpur-Lewis, R. A., Moore, R., Garety, P., Bebbington, P., … Fowler, D. (2015). Urbanicity, persecutory delusions, and clinical intervention: The development of a brief CBT module for helping patients with persecutory delusions enter social urban environments. Behavioural and Cognitive Psychotherapy, 43, 4251.Google Scholar
Garety, P. A., Bebbington, P., Fowler, D., Freeman, D., & Kuipers, E. (2007). Implications for neurobiological research of cognitive models of psychosis: A theoretical paper. Psychological Medicine, 37, 1377.Google Scholar
Garety, P., Kuipers, E., Fowler, D., Freeman, D., & Bebbington, P. (2001). A cognitive model of the positive symptoms of psychosis. Psychological Medicine, 31, 189196.Google Scholar
Goldman-Mellor, S., Margerison-Zilko, C., Allen, K., & Cerdá, M. (2016). Perceived and objectively-measured neighborhood violence and adolescent psychological distress. Journal of Urban Health, 93, 758769.CrossRefGoogle ScholarPubMed
Haddad, L., Schäfer, A., Streit, F., Lederbogen, F., Grimm, O., Wüst, S., … Meyer-Lindenberg, A. (2015). Brain structure correlates of urban upbringing, an environmental risk factor for schizophrenia. Schizophrenia Bulletin, 41, 115122.CrossRefGoogle ScholarPubMed
Häfner, H., Maurer, K., Löffler, W., & Fätkenheuer, B. (1994). The epidemiology of early schizophrenia: Influence of age and gender on onset and early course. British Journal of Psychiatry, 164, 2938.CrossRefGoogle Scholar
Hardt, J., & Rutter, M. (2004). Validity of adult retrospective reports of adverse childhood experiences: Review of the evidence. Journal of Child Psychology and Psychiatry, 45, 260273.CrossRefGoogle ScholarPubMed
Heinz, A., Deserno, L., & Reininghaus, U. (2013). Urbanicity, social adversity and psychosis. World Psychiatry, 12, 187197.CrossRefGoogle ScholarPubMed
Horwood, J., Salvi, G., Thomas, K., Duffy, L., Gunnell, D., Hollis, C., … Wolke, D. (2008). IQ and non-clinical psychotic symptoms in 12-year-olds: Results from the ALSPAC birth cohort. British Journal of Psychiatry, 193, 185191.Google Scholar
Howes, O. D., McCutcheon, R., Owen, M. J., & Murray, R. M. (2017). The role of genes, stress, and dopamine in the development of schizophrenia. Biological Psychiatry, 81, 920.Google Scholar
Kapur, S. (2003). Psychosis as a state of aberrant salience: A framework linking biology, phenomenology, and pharmacology in schizophrenia. American Journal of Psychiatry, 160, 1323.Google Scholar
Kelleher, I., & Cannon, M. (2011). Psychotic-like experiences in the general population: Characterizing a high-risk group for psychosis. Psychological Medicine, 41, 16.Google Scholar
Kelleher, I., Connor, D., Clarke, M. C., Devlin, N., Harley, M., & Cannon, M. (2012). Prevalence of psychotic symptoms in childhood and adolescence: A systematic review and meta-analysis of population-based studies. Psychological Medicine, 42, 18571863.CrossRefGoogle ScholarPubMed
Kelleher, I., Keeley, H., Corcoran, P., Lynch, F., Devlin, N., Molloy, C., … Cannon, M. (2012). Clinicopathological significance of psychotic experiences in non-psychotic young people: Evidence from four population-based studies. British Journal of Psychiatry, 201, 2632.Google Scholar
Kelleher, I., Lynch, F., Harley, M., Molloy, C., Roddy, S., Fitzpatrick, C., & Cannon, M. (2012). Psychotic symptoms in adolescence index risk for suicidal behavior: Findings from 2 population-based case-control clinical interview studies. Archives of General Psychiatry, 69, 12771283.Google Scholar
Kirkbride, J., Stochl, J., Zimbron, J., Crane, C., Metastasio, A., Aguilar, E., … Jones, P. (2015). Social and spatial heterogeneity in psychosis proneness in a multilevel case–prodrome–control study. Acta Psychiatrica Scandinavica, 132, 283292.Google Scholar
Kovacs, M. (1992). Children's Depression Inventory: Manual. North Tonawanda, NY: Multi-Health Systems.Google Scholar
Lederbogen, F., Haddad, L., & Meyer-Lindenberg, A. (2013). Urban social stress—Risk factor for mental disorders. The case of schizophrenia. Environmental Pollution, 183, 26.Google Scholar
Lederbogen, F., Kirsch, P., Haddad, L., Streit, F., Tost, H., Schuch, P., … Meyer-Lindenberg, A. (2011). City living and urban upbringing affect neural social stress processing in humans. Nature, 474, 498501.Google Scholar
Loewy, R. L., Pearson, R., Vinogradov, S., Bearden, C. E., & Cannon, T. D. (2011). Psychosis risk screening with the Prodromal Questionnaire—Brief version (PQ-B). Schizophrenia Research, 129, 4246.Google Scholar
March, J. S., Parker, J. D., Sullivan, K., Stallings, P., & Conners, C. K. (1997). The Multidimensional Anxiety Scale for Children (MASC): Factor structure, reliability, and validity. Journal of the American Academy of Child & Adolescent Psychiatry, 36, 554565.Google Scholar
Millan, M. J., Andrieux, A., Bartzokis, G., Cadenhead, K., Dazzan, P., Fusar-Poli, P., … Weinberger, D. (2016). Altering the course of schizophrenia: Progress and perspectives. Nature Reviews Drug Discovery, 15, 485515.Google Scholar
Milne, B., Moffitt, T., Crump, R., Poulton, R., Rutter, M., Sears, M., … Caspi, A. (2008). How should we construct psychiatric family history scores? A comparison of alternative approaches from the Dunedin Family Health History Study. Psychological Medicine, 38, 17931802.Google Scholar
Moffitt, T. E., & E-Risk Study Team. (2002). Teen-aged mothers in contemporary Britain. Journal of Child Psychology and Psychiatry, 43, 727742.Google Scholar
Myin-Germeys, I., Delespaul, P., & van Os, J. (2005). Behavioural sensitization to daily life stress in psychosis. Psychological Medicine, 35, 733741.Google Scholar
Myin-Germeys, I., van Os, J., Schwartz, J. E., Stone, A. A., & Delespaul, P. A. (2001). Emotional reactivity to daily life stress in psychosis. Archives of General Psychiatry, 58, 11371144.Google Scholar
Newbury, J., Arseneault, L., Caspi, A., Moffitt, T. E., Odgers, C. L., & Fisher, H. L. (2016). Why are children in urban neighborhoods at increased risk for psychotic symptoms? Findings from a UK longitudinal cohort study. Schizophrenia Bulletin, 42, 13721383.Google Scholar
Newbury, J., Arseneault, L., Caspi, A., Moffitt, T. E., Odgers, C. L., & Fisher, H. L. (2017). Cumulative effects of neighborhood social adversity and personal crime victimization on adolescent psychotic experiences. Schizophrenia Bulletin. Advance online publication. doi:10.1093/schbul/sbx060 CrossRefGoogle Scholar
Newbury, J. B., Arseneault, L., Moffitt, T. E., Caspi, A., Danese, A., Baldwin, J. R., & Fisher, H. L. (2017). Measuring childhood maltreatment to predict early-adult psychopathology: Comparison of prospective informant-reports and retrospective self-reports. Journal of Psychiatric Research. Advance online publication . doi:10.1016/j.jpsychires.2017.09.020 Google Scholar
Noone, D., Ames, C., Hassanali, N., Browning, S., Bracegirdle, K., Corrigall, R., … Maddox, L. (2015). A preliminary investigation of schematic beliefs and unusual experiences in children. European Psychiatry, 30, 569575.Google Scholar
Odgers, C. L., Caspi, A., Bates, C. J., Sampson, R. J., & Moffitt, T. E. (2012). Systematic social observation of children's neighborhoods using Google Street View: A reliable and cost-effective method. Journal of Child Psychology and Psychiatry, 53, 10091017.Google Scholar
Odgers, C. L., Caspi, A., Russell, M. A., Sampson, R. J., Arseneault, L., & Moffitt, T. E. (2012). Supportive parenting mediates neighborhood socioeconomic disparities in children's antisocial behavior from ages 5 to 12. Development and Psychopathology, 24, 705721.Google Scholar
Odgers, C. L., Donley, S., Caspi, A., Bates, C. J., & Moffitt, T. E. (2015). Living alongside more affluent neighbors predicts greater involvement in antisocial behavior among low-income boys. Journal of Child Psychology and Psychiatry, 56, 10551064.CrossRefGoogle ScholarPubMed
Odgers, C. L., Moffitt, T. E., Tach, L. M., Sampson, R. J., Taylor, A., Matthews, C. L., & Caspi, A. (2009). The protective effects of neighborhood collective efficacy on British children growing up in deprivation: A developmental analysis. Developmental Psychology, 45, 942.Google Scholar
Office for National Statistics. (2012). The likelihood of becoming a victim of crime: Crime statistics, period ending March 2012. London: Author.Google Scholar
Office for National Statistics. (2013). Urban and rural area definitions for policy purposes in England and Wales: Methodology (v1.0). London: Author.Google Scholar
Plomin, R., DeFries, J. C., Knopik, V. S., & Neiderhiser, J. M. (2013). Behavioral genetics. New York: Worth.Google Scholar
Polanczyk, G., Moffitt, T. E., Arseneault, L., Cannon, M., Ambler, A., Keefe, S. E. R., … Caspi, A. (2010). Etiological and clinical features of childhood psychotic symptoms: Results from a birth cohort. Archives of General Psychiatry, 67, 328338.Google Scholar
Polling, C., Khondoker, M., Hatch, S., Hotopf, M., & South East London Community Health Study Team. (2014). Influence of perceived and actual neighbourhood disorder on common mental illness. Social Psychiatry and Psychiatric Epidemiology, 49, 889901.Google Scholar
Poulton, R., Caspi, A., Moffitt, T. E., Cannon, M., Murray, R. M., & Harrington, H. (2000). Children's self-reported psychotic symptoms and adult schizophreniform disorder: A 15-year longitudinal study. Archives of General Psychiatry, 57, 10531058.Google Scholar
Reuben, A., Moffitt, T. E., Caspi, A., Belsky, D. W., Harrington, H., Schroeder, F., … Danese, A. (2016). Lest we forget: Comparing retrospective and prospective assessments of adverse childhood experiences in the prediction of adult health. Journal of Child Psychology and Psychiatry, 57, 11031112.Google Scholar
Rivera, C. L., Bernal, G., & Rosello, J. (2005). The Children Depression Inventory (CDI) and the Beck Depression Inventory (BDI): Their validity as screening measures for major depression in a group of Puerto Rican adolescents. International Journal of Clinical and Health Psychology, 5, 485.Google Scholar
Robins, L., Cottler, L., Bucholz, K., & Compton, W. (1995). Diagnostic Interview Schedule for DSM-IV (DIS-IV). St Louis, MO: Washington University School of Medicine.Google Scholar
Ronald, A. (2015). Recent quantitative genetic research on psychotic experiences: New approaches to old questions. Current Opinion in Behavioral Sciences, 2, 8188.CrossRefGoogle Scholar
Sampson, R. J., & Raudenbush, S. W. (1999). Systematic social observation of public spaces: A new look at disorder in urban neighborhoods. American Journal of Sociology, 105, 603651.Google Scholar
Sariaslan, A., Fazel, S., D'Onofrio, B., Långström, N., Larsson, H., Bergen, S., … Lichtenstein, P. (2016). Schizophrenia and subsequent neighborhood deprivation: Revisiting the social drift hypothesis using population, twin and molecular genetic data. Translational Psychiatry, 6, e796.Google Scholar
Schoenbaum, M., Sutherland, J. M., Chappel, A., Azrin, S., Goldstein, A. B., Rupp, A., & Heinssen, R. K. (2017). Twelve-month health care use and mortality in commercially insured young people with incident psychosis in the United States. Schizophrenia Bulletin. Advance online publication. doi:10.1093/schbul/sbx009 Google Scholar
Schreier, A., Wolke, D., Thomas, K., Horwood, J., Hollis, C., Gunnell, D., … Duffy, L. (2009). Prospective study of peer victimization in childhood and psychotic symptoms in a nonclinical population at age 12 years. Archives of General Psychiatry, 66, 527536.Google Scholar
Scott, J., Chant, D., Andrews, G., & McGrath, J. (2006). Psychotic-like experiences in the general community: The correlates of CIDI psychosis screen items in an Australian sample. Psychological Medicine, 36, 231238.Google Scholar
Selten, J.-P., van der Ven, E., Rutten, B. P., & Cantor-Graae, E. (2013). The social defeat hypothesis of schizophrenia: An update. Schizophrenia Bulletin, 39, 11801186.CrossRefGoogle ScholarPubMed
Shakoor, S., Zavos, H. M., Haworth, C. M., McGuire, P., Cardno, A. G., Freeman, D., & Ronald, A. (2016). Association between stressful life events and psychotic experiences in adolescence: Evidence for gene–environment correlations. British Journal of Psychiatry, 208, 532538.Google Scholar
Spauwen, J., Krabbendam, L., Lieb, R., Wittchen, H. U., & van Os, J. (2004). Does urbanicity shift the population expression of psychosis? Journal of Psychiatric Research, 38, 613618.Google Scholar
Spauwen, J., Krabbendam, L., Lieb, R., Wittchen, H. U., & van Os, J. (2006). Evidence that the outcome of developmental expression of psychosis is worse for adolescents growing up in an urban environment. Psychological Medicine, 36, 407415.CrossRefGoogle Scholar
Tarullo, A. R., & Gunnar, M. R. (2006). Child maltreatment and the developing HPA axis. Hormones and Behavior, 50, 632639.Google Scholar
Trouton, A., Spinath, F. M., & Plomin, R. (2002). Twins early development study (TEDS): A multivariate, longitudinal genetic investigation of language, cognition and behavior problems in childhood. Twin Research, 5, 444448.CrossRefGoogle ScholarPubMed
Trzesniewski, K. H., Moffitt, T. E., Caspi, A., Taylor, A., & Maughan, B. (2006). Revisiting the association between reading achievement and antisocial behavior: New evidence of an environmental explanation from a twin study. Child Development, 77, 7288.Google Scholar
UNICEF. (2012). Children in an urban world. New York: Author.Google Scholar
van Winkel, R., Stefanis, N. C., & Myin-Germeys, I. (2008). Psychosocial stress and psychosis: A review of the neurobiological mechanisms and the evidence for gene-stress interaction. Schizophrenia Bulletin, 34, 10951105.Google Scholar
Walker, E., Mittal, V., & Tessner, K. (2008). Stress and the hypothalamic pituitary adrenal axis in the developmental course of schizophrenia. Annual Review of Clinical Psychology, 4, 189216.CrossRefGoogle ScholarPubMed
Weissman, M. M., Wickramaratne, P., Adams, P., Wolk, S., Verdeli, H., & Olfson, M. (2000). Brief screening for family psychiatric history: The family history screen. Archives of General Psychiatry, 57, 675682.Google Scholar
Widom, C. S., & Morris, S. (1997). Accuracy of adult recollections of childhood victimization: Part 2. Childhood sexual abuse. Psychological Assessment, 9, 3446.Google Scholar
Widom, C. S., Weiler, B. L., & Cottler, L. B. (1999). Childhood victimization and drug abuse: A comparison of prospective and retrospective findings. Journal of Consulting and Clinical Psychology, 67, 867880.Google Scholar
Wilson, C., Smith, M. E., Thompson, E., Demro, C., Kline, E., Bussell, K., … Schiffman, J. (2016). Context matters: The impact of neighborhood crime and paranoid symptoms on psychosis risk assessment. Schizophrenia Research, 171, 5661.Google Scholar
Yoshizumi, T., Murase, S., Honjo, S., Kaneko, H., & Murakami, T. (2004). Hallucinatory experiences in a community sample of Japanese children. Journal of the American Academy of Child & Adolescent Psychiatry, 43, 10301036.Google Scholar
Zavos, H. M., Freeman, D., Haworth, C. M., McGuire, P., Plomin, R., Cardno, A. G., & Ronald, A. (2014). Consistent etiology of severe, frequent psychotic experiences and milder, less frequent manifestations: A twin study of specific psychotic experiences in adolescence. JAMA Psychiatry, 71, 10491057.Google Scholar
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