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Cause, Care, Cure: Research Priorities for Alzheimer’s Disease and Related Dementias*

  • Paul Stolee (a1), Loretta M. Hillier (a2), Sheila Cook (a3) and Kenneth Rockwood (a4)

Abstract

Part of Ontario’s strategy on Alzheimer’s disease and related dementias (ADRD) was to develop research priorities and recommend strategies for building research capacity. The process to achieve these objectives included an environmental scan, key informant interviews, surveys, and a consensus workshop; this process involved over 100 researchers, clinicians, persons with early dementia, and family caregivers. This article describes the process undertaken, key issues identified, and recommendations for research priorities and for building research capacity; and provides a strategic direction for dementia research in Ontario that is relevant for other jurisdictions. ADRD research in all aspects is required to advance knowledge of ADRD cause, care, and cure; gaps currently exist in understanding effective approaches to care and knowledge transfer. Capacity for high-calibre research hinges on maintaining attractive career paths for researchers, solid infrastructures, and strong partnerships. For research to inform policy and practice, better mechanisms are needed for knowledge exchange.

Une partie de la stratégie de l’Ontario sur la maladie d’Alzheimer et les démences connexes (MADC) était de développer les priorités de recherche et de recommander des stratégies pour le renforcement des capacités de recherche. Le processus adopté pour atteindre ces objectifs comprenaient une analyse de l’environnement, des entretiens avec les informateurs clés, des enquêtes et un atelier de consensus ; ce processus a impliqué plus de 100 chercheurs, cliniciens, les personnes atteintes de démence précoce, et les aidants membres de familles. Ce document décrit le processus entrepris, les principaux problèmes identifiés et les recommandations pour les priorités de recherche et de renforcement des capacités de recherche ; il fournit également une orientation stratégique pour la recherche sur la démence en Ontario qui est pertinente pour d’autres juridictions. La recherche MADC dans tous ses aspects est nécessaire pour faire progresser la connaissance des causes de la démence, les soins et la guérison ; des lacunes existent actuellement dans la compréhension des approches efficaces pour les soins et le transfert des connaissances. La capacité pour la recherche de haut calibre reste sur le maintien de plans de carrière attractifs pour les chercheurs, des infrastructures solides et de partenariats forts. Afin que la recherche informera les politiques et pratiques, de meilleurs mécanismes seront nécessaires pour l’échange de connaissances.

Copyright

Corresponding author

Correspondence and requests for offprints should be sent to / La correspondance et les demandes de tirés-à-part doivent être adressées à: Paul Stolee, Ph.D. School of Public Health and Health Systems 200 University Avenue West University of Waterloo Waterloo, ON N2L 3G1 (stolee@uwaterloo.ca)

Footnotes

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*

This research-priority-setting initiative was funded by the Government of Ontario and managed by the Alzheimer Society of Ontario. We acknowledge Jenna Hollomby for her assistance with the planning and implementation of the consensus workshop. We are grateful for the contributions of all those individuals who participated in this priority setting process, and for guidance received from the members of the project Advisory Committee: Michael Borrie, University of Western Ontario; Larry W. Chambers, Élisabeth Bruyère Research Institute; Lorna de Wit, McMaster University; Sherry Dupuis, University of Waterloo; Nathan Herrmann, University of Toronto; Robert Hopkins, Kingston Psychiatric Hospital; Howard Mount, University of Toronto; Raymond Pong, Laurentian University; Parminder Raina, McMaster University; Nalini Rattan, Alzheimer Society of Canada; Ekaterina Rogaeva, University of Toronto; Jane Rylett, University of Western Ontario; Linda Stebbins, Alzheimer Society of Ontario; and Irene Turpie, McMaster University; and ex-officio members: Elizabeth Esteves, Ontario Seniors’ Secretariat; Angie Szuch, Ontario Seniors’ Secretariat; Eric Hong, Alzheimer Society of Ontario; Michael Klejman, Ontario Ministry of Health and Long-Term Care; and Caroline Lonsdale, Ontario Ministry of Health and Long-Term Care.

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References

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