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Response Recovery Cycles in the Visual Cortex and Superior Colliculus Following Conditioning ‘ON” and ‘OFF” Stimulation in the Rabbit

Published online by Cambridge University Press:  03 July 2018

Stéphane Molotchnikoff  and
Michel Dubuc
Stéphane Molotchnikoff*
Affiliation:
Département de Sciences biologiques, Université de Montréal, C.P. 6128, Montréal (Qué.), Canada, H3C 3J7
Michel Dubuc
Affiliation:
Département de Sciences biologiques, Université de Montréal, C.P. 6128, Montréal (Qué.), Canada, H3C 3J7
*
Département de Sciences biologiques, Université de Montréal C.P. 6128. Montréal, Canada H3C 3J7.
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Summary

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The responsiveness of the visual cortex (VC) and superior colliculus (SC) was simultaneously compared following conditioning “ON” or “OFF” stimulation, in the rabbit.

Average evoked responses were recorded simultaneously from the visual cortex and superior colliculus. “ON” or “OFF” steps constituted the conditioning stimuli whereas the test stimulus consisted of optic nerve stimulation. All evoked responses exhibited a reversal of their polarity when the electrode was moved in the dorsoventral direction (Negative-Positive in the SC, Positive-Negative in the VC). This assured the somato-dentritic origin of the potentials. The results showed that responsiveness in both structures was significantly higher following an “OFF” stimulus than after an “ON” step. Collicular responsiveness was higher than in the VC when the same conditioning stimulus was applied. The spatial distribution of the source of “OFF” responses was circumscribed to the ventral part of the superficial layer of the superior colliculus. These results suggest specific properties associated with the brightening and dimming systems.

Résumé

Résumé

Par la technique du double choc, le cycle de récupération post-réactionnelle (RPR) a été étudié simultanément au niveau du cortex visuel (CV) et au niveau du colliculus supérieur (CS), chez le lapin. Les chocs conditionnant étaient de deux types, soit la stimulation “ON”, soit la stimulation “OFF”. Les réponses tests ont été évoquées par une stimulation du nerf optique, court-circuit ant ainsi l’étape rétinienne. Toutes les réponses ont présenté une inversion de polarité dorsoventrale du CV et du CS, assurant ainsi une origine post-synaptique. Les résultats montrent que l’excitabilité post-réactionnelle est significativement plus élevée après une stimulation conditionnante “OFF” qu’après un conditionnement de type opposé, c’est-à-dire “ON”.

Pour un même type de stimulation conditionnante, la réactivité colliculaire est plus élevée que celle du cortex visuel. Au niveau du colliculus supérieur, les potentiels évoqués par la stimulation “OFF” présentent une distribution spatiale circonscrite à la portion ventrale des couches superficielles du CS. Cette étude permet d’associer des propriétés spécifiques aux systèmes “ON” et “OFF”.

Type
Research Article
Information
Canadian Journal of Neurological Sciences , Volume 4 , Issue 1 , February 1977 , pp. 31 - 37
Copyright
Copyright © Canadian Neurological Sciences Federation 1977

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