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Recurrent Cerebral Infarction during Anticoagulation Therapy in Patients with Mitral Valve Prolapse

Published online by Cambridge University Press:  18 September 2015

Ashfaq Shuaib  and
William F. Murphy
Ashfaq Shuaib*
Affiliation:
Department of Medicine (Neurology), University Hospital, Saskatoon
William F. Murphy
Affiliation:
Calgary General Hospital, Calgary
*
Department of Medicine, Royal University Hospital, Saskatoon, Saskatchewan, Canada S7N 0X0
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Abstract:

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Mitral valve prolapse has been associated with an increased risk of transient or lasting ischemic events. Recurrence is uncommon after initiation of antiplatelet or anticoagulant therapy. In this communication we report two patients, both female, who had mitral valve prolapse as the major risk factor for cerebrovascular disease and who developed cerebral infarction despite anticoagulation. The cerebral infarctions were bilateral and extensive in one patient and led to the patient's death. In the second case, three infarctions resulted in moderate disability.

Type
Original Articles
Information
Canadian Journal of Neurological Sciences , Volume 18 , Issue 2 , May 1991 , pp. 137 - 139
Copyright
Copyright © Canadian Neurological Sciences Federation 1991

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