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Prevalence of Multiple Sclerosis in British Columbia

Published online by Cambridge University Press:  18 September 2015

Vincent P. Sweeney ,
Adele D. Sadovnick  and
Vilma Brandejs
Vincent P. Sweeney*
Affiliation:
Division of Neurology, Department of Medicine, University of British Columbia, Vancouver
Adele D. Sadovnick
Affiliation:
Department of Medical Genetics, University of British Columbia, Vancouver
Vilma Brandejs
Affiliation:
Division of Neurology, Department of Medicine, University of British Columbia, Vancouver
*
Division of Neurology, Department of Medicine, Vancouver General Hospital, #222 - 2775 Heather Street, Vancouver, British Columbia, Canada V5Z 3J5
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Abstract:

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A province wide prevalence study on multiple sclerosis (MS) was conducted in British Columbia (B.C.). The prevalence date was July 1, 1982. The major portion of this study was a review of all the files of neurologists practicing in B.C. as this was judged to be the most accurate source for identifying MS patients. 239,412 neurologists' files were hand searched by one researcher using modified Schumacher criteria for classification. Other sources used during the study for identifying MS patients were the MS Clinic, general practitioners, ophthalmologists, urologists, specialized facilities such as long term care facilities and rehabilitation centres, and patient self-referrals.

A total of 4,620 non-duplicated cases were identified and classified. 4,112 of these (89%) were classified according to information contained in neurologists' records.

The prevalence estimate for definite/probable MS in B.C. was 93.3/100,000 population. This increased to 130.5/100,000 population if possible MS and optic neuritis were also included. These rates are among the highest reported in Canada or elsewhere. The cooperation of B.C. neurologists made this study unique in its scope and accuracy of diagnosis.

Type
Original Articles
Information
Canadian Journal of Neurological Sciences , Volume 13 , Issue 1 , February 1986 , pp. 47 - 51
Copyright
Copyright © Canadian Neurological Sciences Federation 1986

References

REFERENCES

1.McDonald, WI.Multiple Sclerosis: the present position. Acta Neurol Scand 1983; 68: 65–76.CrossRefGoogle ScholarPubMed
2.Ebers, GC.Genetic factors in multiple sclerosis. Neurol Clinics 1983; 1: 645–654.CrossRefGoogle ScholarPubMed
3.Ebers, GC, Bulman, D, Sadovnick, ADet al. A population based twin study in multiple sclerosis. (Abstract) Am J Hum Genet 1984; 36: 49S.Google Scholar
4.Alter, M, Allison, RS, Talbert, ORet al. The geographic distribution of multiple sclerosis. A comparison of prevalence in Charleston County, South Carolina and Halifax County, Nova Scotia. NS Med Bull 1960; 29: 203–210.Google Scholar
5.Hader, WJ.Prevalence of multiple sclerosis in Saskatoon. Can Med Assoc J 1982; 127: 295–297.Google ScholarPubMed
6.Poser, CM.The diagnostic process in multiple sclerosis (Chap l). In: Poser, CM, ed. The Diagnosis of Multiple Sclerosis. New York: Thieme Stratton Inc., 1984; pp3–13.Google Scholar
7.Schumacher, GA, Beebe, G, Kibler, RKet al. Problems of experimental trials of therapy in multiple sclerosis. Report by the panel on the evaluation of experimental trials of therapy in multiple sclerosis. Ann NY Acad Sci 1965; 122: 552–568.CrossRefGoogle Scholar
8.Rose, AS, Ellison, GW, Myers, LWet al. Criteria for the clinical diagnosis of multiple sclerosis. Neurology 1976; 26: 20–22.CrossRefGoogle ScholarPubMed
9.McDonald, WI, Halliday, AM.Diagnosis and classification of multiple sclerosis. Br Med Bull 1977; 33: 4–8.CrossRefGoogle ScholarPubMed
10.White, DN, Wheelan, L.Disseminated sclerosis. A survey of patients in the Kingston Ontario area. Neurology 1959; 9: 256–272.CrossRefGoogle ScholarPubMed
11.Stazio, A, Kurland, LT, Bells, LGet al. Multiple sclerosis in Winnipeg, Manitoba. Methodological considerations of epidemiologic survey. Ten year follow up of a community wide study and population survey. J Chron Dis 1964; 17: 415–438.CrossRefGoogle Scholar
12.Bennett, J, Hamilton, R, Neutel, CLet al. Survey of persons with multiple sclerosis in Ottawa, 1974-1975. Can J Public Health 1977; 68: 141–147.Google Scholar
13.Pryse-Phillips, WEM, Cook, SD, Galway, B.Incidence and prevalence of multiple sclerosis in Newfoundland and Labrador: Baseline results. (Abstract) Can J Neurol Sci 1983; 10: 111.Google Scholar
14.Kurtzke, JF.Epidemiologic contributions to multiple sclerosis: An overview. Neurology 1980; 30: 61–79.CrossRefGoogle ScholarPubMed
15.Statistics Canada. 1981. Census Information.Google Scholar
16.Visscher, BR, Detels, R, Coulson, AHetal. Latitude, migration, and the prevalence of multiple sclerosis. Am J Epidemiol 1977; 106: 470–475.CrossRefGoogle ScholarPubMed
17.Baum, HM, Rothschild, BB.The incidence and prevalence of reported multiple sclerosis. Ann Neurol 1981; 10: 420–428.CrossRefGoogle ScholarPubMed