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Persistent Hemiballismus with Lesions Outside the Subthalamic Nucleus

Published online by Cambridge University Press:  18 September 2015

Anthony E. Lang
Anthony E. Lang*
Affiliation:
Movement Disorders Unit, Toronto Western Hospital
*
Division of Neurology, Toronto General Hospital, 25 Leonard Ave., Toronto. Ontario. Canada. M5T 2R2
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Abstract:

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Two patients are reported with hemiballismus due to lesions in the striatum as documented on CT scan. The involuntary movements persisted for one and five years respectively. A third patient with more typical self-limited hemiballismus had no evidence of a causative lesion on CT scan. It is proposed that lesions outside the subthalamic nucleus of Luys may interfere with the compensatory mechanisms which can result in the spontaneous resolution of hemiballistic movements. None of the patients benefited from the use of sodium valproate therapy, however, pimozide reduced the severity of the dyskinesia in the two with longstanding hemiballismus.

Type
Original Articles
Information
Canadian Journal of Neurological Sciences , Volume 12 , Issue 2 , May 1985 , pp. 125 - 128
Copyright
Copyright © Canadian Neurological Sciences Federation 1985

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