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Myoclonies du voile associées à une diminution de l’acide 5-hydroxy-indole-acétique céphalo-rachidien et répondant au clonazepam

Published online by Cambridge University Press:  18 September 2015

S. Gauthier ,
S.N. Young  and
D.W. Baxter
S. Gauthier*
Affiliation:
De l’Institut et Hôpital Neurologique de Montréal, Département de Neurologie et de Neurochirurgie, Université McGill et le Département de Psychiatrie, Université McGill
S.N. Young
Affiliation:
De l’Institut et Hôpital Neurologique de Montréal, Département de Neurologie et de Neurochirurgie, Université McGill et le Département de Psychiatrie, Université McGill
D.W. Baxter
Affiliation:
De l’Institut et Hôpital Neurologique de Montréal, Département de Neurologie et de Neurochirurgie, Université McGill et le Département de Psychiatrie, Université McGill
*
Institut Neurologique de Montréal, 3801, rue Université, Montréal, Québec, Canada H3A 2B4
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Summary

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A patient presenting with palatal myoclonus was diagnosed as suffering from possible multiple sclerosis. A reduction of cerebrospinal 5-hydroxy-indole-acetic acid suggested a decreased central serotonergic turnover. A therapeutic trial with clonazepam, a serotonergic agonist, improved the myoclonus symptomatically. The possible involvement of serotonergic inhibitory systems in the expression of palatal myoclonus is discussed.

Type
Research Article
Information
Canadian Journal of Neurological Sciences , Volume 8 , Issue 1 , February 1981 , pp. 51 - 54
Copyright
Copyright © Canadian Neurological Sciences Federation 1981

References

Bibliographie

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