Hostname: page-component-5c6d5d7d68-pkt8n Total loading time: 0 Render date: 2024-08-07T00:57:14.104Z Has data issue: false hasContentIssue false

Multiple Sclerosis and Associated Diseases: A Relationship to Diabetes Mellitus

Published online by Cambridge University Press:  18 September 2015

S. Warren
Affiliation:
the Department of Community Medicine, and the Multiple Sclerosis Research Clinic, Department of Medicine, University of Alberta, Edmonton, Alberta
K.G. Warren*
Affiliation:
the Department of Community Medicine, and the Multiple Sclerosis Research Clinic, Department of Medicine, University of Alberta, Edmonton, Alberta
*
Department of Community Medicine, University of Alberta, Edmonton, Alberta, Canada T6G 2G3
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

One hundred multiple sclerosis (MS) patients and hospital controls were compared for coexisting illnesses, and other illnesses among their family members. The patients and controls were compared for allergy, migraine, and cancer among themselves and for a family history of these illnesses. The findings were negative. However a relationship was found between multiple sclerosis and diabetes mellitus. More MS patients than controls were either diabetic or reported a blood relative with diabetes. MS patients who reported another blood relative with MS were also more likely to report a family history of diabetes mellitus than MS patients who had no other relative with multiple sclerosis.

Type
Research Article
Copyright
Copyright © Canadian Neurological Sciences Federation 1981

References

Agranoff, B.W. and Goldberg, D. (1974). Diet and the geographical distribution of multiple sclerosis. Lancet, 2: 106167.CrossRefGoogle ScholarPubMed
Alter, M. (1977). Clues to the cause based upon the epidemiology of MS. In Multiple Sclerosis. A Critical Conspectus, Field, E.J. (Ed.) University Park Press, Baltimore.Google Scholar
Andermann, E., Remillard, G.M., Goyer, G. et al. (1976). Genetic and family studies in Friedreich’s Ataxia. Can. J. Neurol. Sci., 3: 287301.CrossRefGoogle ScholarPubMed
Butcher, J. (1976). The distribution of multiple sclerosis in relation to the dairy industry and milk consumption. N.Z. Med. J., 83: 566–73.Google Scholar
Craelius, W. (1978). Comparative epidemiology of multiple sclerosis and dental caries. J. Epid. Comm. Med., 32: 155–65.Google ScholarPubMed
Craelius, W., Newby, N. and Thomas, F.C. (1978). Central myelination in vitro: effect of reduced calcium and magnesium. Neurological Absts.Google Scholar
Dick, G. (1976). The etiology of multiple sclerosis. Proc. R. Soc. Med. 69: 611–15.Google ScholarPubMed
Ehrentheil, O., Schulman, M. and Alexander, L. (1952). Role of food allergy in multiple sclerosis. Neurology, 2: 412–27.CrossRefGoogle ScholarPubMed
Frovig, A., Presthus, J. and Sponheim, N. (1967). The significance of allergy in the etiology and pathogenesis of multiple sclerosis. Acta Psych. (Scand.), 43: 215–25.Google ScholarPubMed
Gertner, J., Horst, R. and Tamborlane, W. (1979). Mineral metabolism and vitamin D status in juvenile diabetics: changes following normalization of plasma glucose. Presented at 39th Annual Meeting of the American Diabetes Association, Los Angeles.Google Scholar
Goldberg, P. (1974). Multiple sclerosis: vitamin D and calcium as environmental determinants of prevention. Parts I and II. Internat. J. Environ. Studies, 6: 1927, 121–29.CrossRefGoogle Scholar
Hess, A.Rickets, Osteomalacia and Tetany. Lea and Febiger, Philadelphia, 1929.Google Scholar
Hewer, R.L. and Robinson, M. (1968). Diabetes mellitis in Friedreich’s ataxia. J. Neurol. uoNeurosurg. Psychi., 31: 226–31.CrossRefGoogle Scholar
Hoskins, B., Feibelman, R., Loury, A. et al. (1979). Effectiveness of insulin therapy on altered renal calcium transport in diabetic rats. Diabetes, 28: 108894.CrossRefGoogle Scholar
Kloster, J. (1931). Distribution and frequency of rickets in one fishery district of Finmark and relation to diet disorder. Acta Paed., 12 (Suppl. 3): 1.Google Scholar
Kurland, L. and Reed, D. (1964). Geographic and climatic aspects of multiple sclerosis. A.J.P.H. 54: 588–97.Google ScholarPubMed
Leibowitz, U. and Alter, M. (1973). Multiple Sclerosis: Clues to its Cause. North Holland, Amsterdam.Google Scholar
Limburg, C. (1950). The geographic distribution of multiple sclerosis and its estimated prevalence in the U.S. In Multiple Sclerosis and the Demyelinating Diseases. Williams and Wilkins, Baltimore.Google Scholar
McAlpine, D. and Compston, M.D. (1952). Some aspects of the natural history of disseminated sclerosis. Q.J. Med., 21: 135–67.Google ScholarPubMed
Merton, and Meade, C.J. (1977). Relevance of fatty acids in Multiple Sclerosis. Brit. Med. Bull., 33: 6774.CrossRefGoogle Scholar
Raskin, P., Stevenson, M., Barilla, D. et al (1978). The hypercalciuria of diabetes mellitus: its amelioration with insulin. Presented at the 38th Annual Meeting of the American Diabetes Association, Boston.CrossRefGoogle Scholar
Sherwin, R. and Felig, P.Pathophysiology of diabetes mellitus. In Symposium on Diabetes Mellitus. Medical Clinics, of Poldolsky, N.A.S. (Ed.). W.B. Saunders Co., Philadelphia. 1978.Google Scholar
Sibley, W.A., Bamford, D. and Laquna, F. (1978). Anamnestic studies in multiple sclerosis: a relationship between familial multiple sclerosis and neoplasia. Neurology, 28: 125–29.CrossRefGoogle ScholarPubMed
Swank, R.L., Lersted, O., Strom, A. and Backer, J. (1952). Multiple Sclerosis in rural Norway. New Engl. J. Med., 246: 721–28.CrossRefGoogle ScholarPubMed
Thoren, C. (1962). Diabetes mellitus in Friedreich’s Ataxia. Acta Paed., Suppl. 135: 239–47.CrossRefGoogle ScholarPubMed
Visscher, B., Detels, R., Coulson, A. et al. (1977). Latitude, migration and the prevalence of multiple sclerosis. Amer. J. Epid., 106: 470–75.CrossRefGoogle ScholarPubMed
Verdy, M. (1977). Multiple sclerosis and milk. C.M.A.J., 9: 117.Google Scholar
Watkins, S. and Espir, M. (1969). Migraine and multiple sclerosis. J. Neuro. Neurosurg. Psychiat., 32: 3537.CrossRefGoogle ScholarPubMed