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The Incorporation of 3H (G) L-Leucine into Single Muscle Fibers in Duchenne Dystrophy and Charcot-Marie Tooth Disease

Published online by Cambridge University Press:  18 September 2015

George Monckton  and
Halyna Marusyk
George Monckton*
Affiliation:
Division of Neurology, Department of Medicine, University of Alberta
Halyna Marusyk
Affiliation:
Division of Neurology, Department of Medicine, University of Alberta
*
9-101 Clinical Science Bldg. University of Alberta, Edmonton, Canada. T6G 2G3.
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Summary

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The results are reported of single muscle fiber uptake of tritiated leucine in muscle biopsy material from Duchenne dystrophy and Charcot-Marie Tooth disease. The uptake in the two conditions is compared and suggests that the previously reported increase in synthesis of cytoplasmic proteins in muscular dystrophy are probably related to regenerative efforts by the muscle fibers.

Type
Research Article
Information
Canadian Journal of Neurological Sciences , Volume 6 , Issue 1 , February 1979 , pp. 53 - 57
Copyright
Copyright © Canadian Neurological Sciences Federation 1979

References

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