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Glucose and Insulin Metabolism in Friedreich's Ataxia

  • D. Shapcott (a1), S. Melancon (a1), R.F. Butterworth (a1), K. Khoury (a1), R. Collu (a1), G. Breton (a1), G. Geoffroy (a1), B. Lemieux (a1) and A. Barbeau (a1)...

Summary:

Our prospective survey of 50 ataxic patients confirms the previous finding of frequent clinical or chemical diabetes in Friedreich's ataxia. Eighteen percent of our typical cases have clinical diabetes and 40% at least an abnormal glucose tolerance curve. However, this finding does not appear to be specific to that form of ataxia. Furthermore, we have shown that most patients with ataxia have normal or low fasting insulin levels, but a hyperinsulinic response to a glucose load.

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Copyright

Corresponding author

Clinical Research Institute of Montreal, 110 Pine Avenue West, H2W 1R7 Montreal, Quebec, Canada

References

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Glucose and Insulin Metabolism in Friedreich's Ataxia

  • D. Shapcott (a1), S. Melancon (a1), R.F. Butterworth (a1), K. Khoury (a1), R. Collu (a1), G. Breton (a1), G. Geoffroy (a1), B. Lemieux (a1) and A. Barbeau (a1)...

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