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F-wave and Cervical Somatosensory Response Conduction from the Seventh Cervical Spinous Process to Cortex in Multiple Sclerosis

  • Andrew Eisen (a1) and Kenneth Nudleman (a1)

Summary:

Transit (conduction) times from the wrist to the seventh cervical spinous process (C7) were measured by using the F-wave response (TA) and the cervical somatosensory response (SEPC). The mean values obtained in 25 controls were 10.1 ± 0.9 s-3 and 10.9 ± 1.0 s-3 respectively. The 0.8 ± 1.0 s-3 difference between the two methods represents central delay of SEPC, possibly at the level of the dorsal root ganglion. The mean onset latency of the cortical somatosensory response (SEPA) evoked by median nerve stimulation in the same subjects was 15.5 ± 1.0 s-3. Transit time from C7 to the cortex (TB) given by either SEPA - TA or SEPA - SEPC - 0.8, where 0.8 is the necessary corrective factor for central delay of SEPC, was 5.3 ± 1.0 s-3. These techniques were applied to 10 patients suspected of having multiple sclerosis, but without clinical evidence of involvement above C7. Six of the 10 cases showed prolongation of TB. In 4 of these, this could only be calculated by the F-wave method since SEPC was absent. It is concluded that transit times derived from either the F-wave or SEPC are equally valid and interchangeable. The absence of one response allows for its replacement by the other.

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Copyright

Corresponding author

Montreal Neurological Hospital, 3801 University Street, Montreal, Quebec, H3A 2B4, Canada.

References

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Bynke, H., Olsson, J.E. and Rosen, I. (1977). Diagnostic value of visual evoked response, clinical eye examination and CSF analysis in chronic myelopathy. Acta Neurologica Scandinavica 56, 5569.
Cracco, R.Q. and Cracco, J.B. (1976). Somatosensory evoked potential in man: Far field potentials. Electroencephalography and Clinical Neurophysiology 41, 460466.
Dawson, G.D. (1956). The relative excitability and conduction velocity of sensory and motor fibers in man. Journal of Physiology (Lond.) 131, 436451.
Dorfman, L.J. (1977). Indirect estimation of spinal cord conduction velocity in man. Electroencephalography and Clinical Neurophysiology, 42, 2634.
Eisen, A. and Nudleman, K. (In press). Cord to cortex conduction in multiple sclerosis. Neurology (Minneapolis).
Eisen, A., Schomer, D. and Melmed, C. (1977a). The application of F wave measurements in the differentiation of proximal and distal upper limb entrapments. Neurology (Minneapolis) 27, 662668.
Eisen, A., Schomer, D. and Melmed, C. (1977b). An electrophysiological method for examining lumbosacral root compression. The Canadian Journal of Neurological Sciences, 4, 117123.
Gärde, A. and Kjellin, K.G. (1971). Diagnostic significance of cerebrospinal fluid examinations in myelopathy. Acta Neurologica Scandinavica, 47, 555568.
Gassel, M.M. and Wiesendanger, M. (1965). Recurrent and reflex discharges in plantar muscles of the cat. Acta Physiologica Scandinavica, 65, 138142.
Goff, W.R., Rosner, B.S. and Allison, T. (1962). Distribution of cerebral somatosensory evoked responses in normal man. Electroencephalography and Clinical Neurophysiology, 14, 697713.
Kimura, J. (1974). F wave velocity in the central segment of the median and ulnar nerves. A study in normals and in Charcot-Marie-Tooth disease. Neurology (Minneapolis) 24, 539546.
Leibowitz, U. and Alter, M. (1973). Multiple sclerosis: Clues to its cause. North-Holland Publishing Co., (Amsterdam), pp. 83117.
Leibowitz, U. and Halpern, L. and Alter, M. (1967). Clinical studies of multiple sclerosis in Israel. V. Progressive spinal syndromes and multiple sclerosis. Neurology (Minneapolis) 17, 988992.
Link, H., Norrby, E. and Olsson, J.E. (1976) Immunoglobulin abnormalities and measles antibody responses in chronic myelopathy. Archives of Neurology (Chicago) 33, 2632.
Magladery, J.W. and McDougal, D.B. (1950). Electrophysiology of nerve and reflex activity in normal man. I. Identification of certain reflexes in the electromyogram and the conduction velocity of peripheral nerve fibers. Bulletin of the Johns Hopkins Hospital, 86, 265290.
Magladery, J.W., Porter, W.E., Park, A.M. and Teasdall, R.D. (1951). Electrophysiological studies of nerve and reflex activity in normal man. IV. The two-neurone reflex and identification of certain action potentials from spinal roots and cord. Bulletin of the Johns Hopkins Hospital, 88, 499519.
Matthews, W.B., Beauchamp, M. and Small, D.G. (1974). Cervical somatosensory evoked responses in man. Nature, 252, 230232.
Mayer, R.F. and FEldman, R.G, (1967). Observations on the nature of the F wave in man. Neurology (Minneapolis) 17, 147156.
McAlpine, D. and Compston, N. (1952). Some aspects of the natural history of disseminated sclerosis. Quarterly Journal of Medicine. 2l. 135167.
McDonald, W.I. and Halliday, A.M. (1977). Diagnosis and classification of multiple sclerosis. British Medical Bulletin, 33, 48.
McLeod, J.G. and Wray, S.H. (1966). An experimental study of the F wave in the baboon. Journal of Neurology, Neurosurgery and Psychiatry, 29, 196200.
Miglietta, O.E. (1973). The F response after transverse myelotomy. In: New Developments in Electromyography and Clinical Neurophysiology, vol. 3, pp. 323327, edited by Desmedt, J.E.. Karger: Basel.
Renshaw, B. (1941). Influence of discharge of motor neurons upon excitation of neighbouring motor neurons. Journal of Neurophysiology, 4, 167183.
Small, D.G., Beauchamp, M. and Matthews, W.B. (1977). Spinal evoked potentials in multiple sclerosis. Electroencephalography and Clinical Neurophysiology, 42, 141 (abstract).
Thorne, J. (1965). Central responses to electrical activation of the peripheral nerves supplying the intrinsic hand muscle. Journal of Neurology, Neurosurgery and Psychiatry, 28, 482495.
Tsumoto, T., Hirose, N., Nonaka, S. and Takahashi, M. (1972). Analysis of somatosensory evoked potentials to lateral popliteal nerve stimulation in man. Electroencephalography and Clinical Neurophysiology, 33, 379388.
Upton, A.R.M., McComas, A.J. and Sica, R.E.P. (1971). Potentiation of “late” responses evoked in muscles during effort. Journal of Neurology, Neurosurgery and Psychiatry, 34, 699711.

F-wave and Cervical Somatosensory Response Conduction from the Seventh Cervical Spinous Process to Cortex in Multiple Sclerosis

  • Andrew Eisen (a1) and Kenneth Nudleman (a1)

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