Hostname: page-component-84b7d79bbc-7nlkj Total loading time: 0 Render date: 2024-07-30T20:56:43.986Z Has data issue: false hasContentIssue false

Failure to Recognize Status Epilepticus in a Paralysed Patient

Published online by Cambridge University Press:  18 September 2015

R.I. Munn*
Affiliation:
Department of Paediatric Neurology, University of British Columbia, Vancouver
K. Farrell*
Affiliation:
Department of Paediatric Neurology, University of British Columbia, Vancouver
*
Neurology Department, British Columbia's Children's Hospital, 4480 Oak Street, Vancouver, British Columbia, Canada V6H 3V4
Rights & Permissions [Opens in a new window]

Abstract:

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Paralysis induced by neuromuscular blocking agents facilitates ventilation of seriously ill patients but may preclude clinical recognition of seizures. We describe the occurrence of severe cognitive impairment in a 14-year-old girl in whom status epilepticus was recognized only when pancuronium was withdrawn after 14 hours of paralysis. This patient emphasizes a potential danger of paralysis from drugs in patients with acute cerebral dysfunction.

Type
Research Article
Copyright
Copyright © Canadian Neurological Sciences Federation 1993

References

REFERENCES

1.Duffy, TE, Howse, DC, Plum, F. Cerebral energy metabolism during experimental status epilepticus. J Neurochem 1975; 24: 925934.CrossRefGoogle ScholarPubMed
2.Meldrum, BS, Vigouroux, RA, Rage, P, Brierley, JB. Hippocampal lesions produced by prolonged seizures in paralysed artificially ventilated baboons. Experientia 1973; 29: 561563.CrossRefGoogle Scholar
3.Wasterlain, CG. Mortality and morbidity from serial seizures. Epilepsia 1974; 15: 155176.CrossRefGoogle ScholarPubMed
4.Aicardi, J, Chevrie, JJ. Convulsive status epilepticus in infants and children. A study of 239 cases. Epilepsia 1970; 11: 187197.Google ScholarPubMed
5.Yager, JY, Cheang, M, Seshia, SS. Status epilepticus in children. Can J Neurol Sci 1988; 15:402405.CrossRefGoogle ScholarPubMed
6.Maytal, J, Shinnar, S, Moshe, SL, Alvarez, LA. Low morbidity and mortality of status epilepticus in children. Pediatrics 1989; 83: 323331.CrossRefGoogle ScholarPubMed
7.Eyre, JA, Oozeer, RC, Wilkinson, AR. Continuous electroencephalo-graphic recording to detect seizures in paralysed newborn babies. Brit Med J 1983; 286: 10171018.CrossRefGoogle Scholar
8.Coen, RW, McCutchen, CB, Wermer, D, Snyder, J, Gluck, FE. Continuous monitoring of the electroencephalogram following perinatal asphyxia. J Pediatr 1982; 100: 628630.CrossRefGoogle ScholarPubMed
9.Talwar, D, Torres, F. Continuous electrophysiologic monitoring of cerebral function in the pediatric intensive care unit. Pediatr Neurol 1988; 4: 137147.CrossRefGoogle ScholarPubMed
10.Prior, PF, Virden, RSM, Maynard, DE. An EEG device for monitoring seizure discharges. Epilepsia 1973; 14: 367372.CrossRefGoogle ScholarPubMed
11.Partinen, M, Kovanen, J, Nilsson, E. Status epilepticus treated by barbiturate anaesthesia with continuous monitoring of cerebral function. Brit Med J 1981; 282: 520521.CrossRefGoogle ScholarPubMed
12.Hellström-Westas, L, Rosin, I, Swenningsen, NW. Silent seizures in sick infants in early life - diagnosis by continuous cerebral function monitoring. Acta Paediatr Scand 1985; 74: 741748.CrossRefGoogle ScholarPubMed