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The role of methionine and vitamin B12in folate incorporation by rat liver

Published online by Cambridge University Press:  25 February 2008

P. G McGing  and
J. M. Scott
P. G McGing
Affiliation:
Department of Biochemistry, Trinity College, Dublin 2, Ireland
J. M. Scott
Affiliation:
Department of Biochemistry, Trinity College, Dublin 2, Ireland
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Abstract

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The decreased folate uptake induced by exposure of rats to nitrous oxide can be partly reversed by methionine supplementation. This is consistent with the theory that N2O inhibits methylcobalamindependent methionine synthetase (EC 2.1.1.13) in rat liver and previous observations showing decreased folate incorporation in rats made nutritionally vitamin B12 deficient.

Type
Short Papers
Information
British Journal of Nutrition , Volume 43 , Issue 1 , January 1980 , pp. 235 - 237
Copyright
Copyright © The Nutrition Society 1980

References

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