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New perspectives on nutritional interventions to augment lipid utilisation during exercise

  • Javier T. Gonzalez (a1) and Emma J. Stevenson (a1)


The enhancement of fat oxidation during exercise is an aim for both recreational exercising individuals and endurance athletes. Nutritional status may explain a large part of the variation in maximal rates of fat oxidation during exercise. This review reveals novel insights into nutritional manipulation of substrate selection during exercise, explaining putative mechanisms of action and evaluating the current evidence. Lowering the glycaemic index of the pre-exercise meal can enhance lipid utilisation by up to 100 % through reduced insulin concentrations, although its application may be restricted to specific training sessions rather than competition. Chronic effects of dietary glycaemic index are less clear and warrant future study before firm recommendations can be made. A flurry of recent advances has overthrown the conventional view of l-carnitine supplementation, with skeletal muscle uptake possible under certain dietary conditions and providing a strategy to influence energy metabolism in an exercise intensity-dependent manner. Use of non-carbohydrate nutrients to stimulate muscle l-carnitine uptake may prove more beneficial for optimising lipid utilisation, but this requires more research. Studies investigating fish oil supplementation on fat oxidation during exercise are conflicting. In spite of some strong putative mechanisms, the only crossover trial showed no significant effect on lipid use during exercise. Ca may increase NEFA availability although it is not clear whether these effects occur. Ca and caffeine can increase NEFA availability under certain circumstances which could theoretically enhance fat oxidation, yet strong experimental evidence for this effect during exercise is lacking. Co-administration of nutrients to maximise their effectiveness needs further investigation.

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*Corresponding author: J. T. Gonzalez, email


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1 Venables, MC, Achten, J & Jeukendrup, AE (2005) Determinants of fat oxidation during exercise in healthy men and women: a cross-sectional study. J Appl Physiol 98, 160167.
2 De Bock, K, Derave, W, Eijnde, BO, et al. (2008) Effect of training in the fasted state on metabolic responses during exercise with carbohydrate intake. J Appl Physiol 104, 10451055.
3 Achten, J & Jeukendrup, AE (2001) Optimizing fat oxidation through exercise and diet. Nutrition 20, 716727.
4 Frayn, KN (2010) Fat as a fuel: emerging understanding of the adipose tissue-skeletal muscle axis. Acta Physiol 199, 509518.
5 Romijn, JA, Coyle, EF, Sidossis, LS, et al. (1995) Relationship between fatty acid delivery and fatty acid oxidation during strenuous exercise. J Appl Physiol 79, 19391945.
6 Bruce, CR & Hawley, JA (2004) Improvements in insulin resistance with aerobic exercise training: a lipocentric approach. Med Sci Sports Exerc 36, 11961201.
7 Van Proeyen, K, Szlufcik, K, Nielens, H, et al. (2010) Training in the fasted state improves glucose tolerance during fat-rich diet. J Physiol 588, 42894302.
8 Frayn, KN (2010) Fat as a fuel: emerging understanding of the adipose tissue-skeletal muscle axis. Acta Physiol (Oxf) 199, 509518.
9 Hawley, JA, Brouns, F & Jeukendrup, A (1998) Strategies to enhance fat utilisation during exercise. Sports Med 25, 241257.
10 Jenkins, D, Wolever, T, Taylor, R, et al. (1981) Glycemic index of foods: a physiological basis for carbohydrate exchange. Am J Clin Nutr 34, 362366.
11 Granfeldt, Y, Hagander, B & Bjorck, I (1995) Metabolic responses to starch in oat and wheat products. On the importance of food structure, incomplete gelatinization or presence of viscous dietary fibre. Eur J Clin Nutr 49, 189199.
12 Goddard, M, Young, G & Marcus, R (1984) The effect of amylose content on insulin and glucose responses to ingested rice. Am J Clin Nutr 39, 388392.
13 Haber, G, Heaton, K, Murphy, D, et al. (1977) Depletion and disruption of dietary fibre: effects on satiety, plasma-glucose, and serum-insulin. Lancet 310, 679682.
14 Todesco, T, Rao, A, Bosello, O, et al. (1991) Propionate lowers blood glucose and alters lipid metabolism in healthy subjects. Am J Clin Nutr 54, 860865.
15 Frayn, KN (2003) The glucose-fatty acid cycle: a physiological perspective. Biochem Soc Trans 31, 11151119.
16 Díaz, EO, Galgani, JE & Aguirre, CA (2006) Glycaemic index effects on fuel partitioning in humans. Obes Rev 7, 219226.
17 Ritz, P, Krempf, M, Cloarec, D, et al. (1991) Comparative continuous-indirect-calorimetry study of two carbohydrates with different glycemic indices. Am J Clin Nutr 54, 855859.
18 Korach-Andre, M, Roth, H, Barnoud, D, et al. (2004) Glucose appearance in the peripheral circulation and liver glucose output in men after a large 13C starch meal. Am J Clin Nutr 80, 881886.
19 Diaz, EO, Galgani, JE, Aguirre, CA, et al. (2005) Effect of glycemic index on whole-body substrate oxidation in obese women. Int J Obes Relat Metab Disord 29, 108114.
20 Vaitheesvaran, B, LeRoith, D & Kurland, I (2010) MKR mice have increased dynamic glucose disposal despite metabolic inflexibility, and hepatic and peripheral insulin insensitivity. Diabetologia 53, 22242232.
21 Sparti, A, Milon, H, Di Vetta, V, et al. (2000) Effect of diets high or low in unavailable and slowly digestible carbohydrates on the pattern of 24-h substrate oxidation and feelings of hunger in humans. Am J Clin Nutr 72, 14611468.
22 Tappy, L, Wursch, P, Randin, J, et al. (1986) Metabolic effect of pre-cooked instant preparations of bean and potato in normal and in diabetic subjects. Am J Clin Nutr 43, 3036.
23 Stevenson, EJ, Astbury, NM, Simpson, EJ, et al. (2009) Fat oxidation during exercise and satiety during recovery are increased following a low-glycemic index breakfast in sedentary women. J Nutr 139, 890897.
24 Thomas, DE, Brotherhood, JR & Brand, JC (1991) Carbohydrate feeding before exercise: effect of glycemic index. Int J Sports Med 12, 180186.
25 Sparks, M, Selig, S & Febbraio, M (1998) Pre-exercise carbohydrate ingestion: effect of the glycemic index on endurance exercise performance. Med Sci Sports Exerc 30, 844849.
26 Stevenson, EJ, Williams, C, Mash, LE, et al. (2006) Influence of high-carbohydrate mixed meals with different glycemic indexes on substrate utilization during subsequent exercise in women. Am J Clin Nutr 84, 354360.
27 Wee, SL, Williams, C, Tsintzas, K, et al. (2005) Ingestion of a high-glycemic index meal increases muscle glycogen storage at rest but augments its utilization during subsequent exercise. J Appl Physiol 99, 707714.
28 DeMarco, HM, Sucher, KP, Cisar, CJ, et al. (1999) Pre-exercise carbohydrate meals: application of glycemic index. Med Sci Sports Exerc 31, 164170.
29 Stevenson, E, Williams, C, McComb, G, et al. (2005) Improved recovery from prolonged exercise following the consumption of low glycemic index carbohydrate meals. Int J Sport Nutr Exerc Metab 15, 333349.
30 Steinberg, GR (2009) Role of the AMP-activated protein kinase in regulating fatty acid metabolism during exercise. Appl Physiol Nutr Metab 34, 315322.
31 Stevenson, E, Williams, C, Nute, M, et al. (2005) The effect of the glycemic index of an evening meal on the metabolic responses to a standard high glycemic index breakfast and subsequent exercise in men. Int J Sport Nutr Exerc Metab 15, 308322.
32 Stevenson, E, Williams, C, Nute, M, et al. (2008) Influence of the glycaemic index of an evening meal on substrate oxidation following breakfast and during exercise the next day in healthy women. Eur J Clin Nutr 62, 608616.
33 Grill, V & Qvigstad, E (2000) Fatty acids and insulin secretion. Br J Nutr 83, S79S84.
34 Wolever, T & Bolognesi, C (1996) Time of day influences relative glycaemic effect of foods. Nutr Res 16, 381384.
35 Nilsson, A, Granfeldt, Y, Ostman, E, et al. (2006) Effects of GI and content of indigestible carbohydrates of cereal-based evening meals on glucose tolerance at a subsequent standardised breakfast. Eur J Clin Nutr 60, 10921099.
36 Gao, Z, Yin, J, Zhang, J, et al. (2009) Butyrate improves insulin sensitivity and increases energy expenditure in mice. Diabetes 58, 15091517.
37 Fardet, A (2010) New hypotheses for the health-protective mechanisms of whole-grain cereals: what is beyond fibre? Nutr Res Rev 23, 65134.
38 Stevenson, E, Williams, C & Nute, M (2005) The influence of the glycaemic index of breakfast and lunch on substrate utilisation during the postprandial periods and subsequent exercise. Br J Nutr 93, 885893.
39 Tittelbach, TJ, Mattes, RD & Gretebeck, RJ (2000) Post-exercise substrate utilization after a high glucose vs. high fructose meal during negative energy balance in the obese. Obes Res 8, 496505.
40 Burelle, Y, Lamoureux, MC, Peronnet, F, et al. (2006) Comparison of exogenous glucose, fructose and galactose oxidation during exercise using 13C-labelling. Br J Nutr 96, 5661.
41 Henry, RR, Crapo, PA & Thorburn, AW (1991) Current issues in fructose metabolism. Annu Rev Nutr 11, 2139.
42 Fredholm, BB (1971) The effect of lactate in canine subcutaneous adipose tissue in situ. Acta Physiol Scand 81, 110123.
43 Liu, C, Wu, J, Zhu, J, et al. (2009) Lactate inhibits lipolysis in fat cells through activation of an orphan G-protein-coupled receptor, GPR81. J Biol Chem 284, 28112822.
44 Rooney, K & Trayhurn, P (2011) Lactate and the GPR81 receptor in metabolic regulation: implications for adipose tissue function and fatty acid utilisation by muscle during exercise. Br J Nutr 106, 13101316.
45 Tappy, L & Le, K-A (2010) Metabolic effects of fructose and the worldwide increase in obesity. Physiol Rev 90, 2346.
46 Moore, LJS, Midgley, AW, Thomas, G, et al. (2009) The effects of low- and high-glycemic index meals on time trial performance. Int J Sports Physiol Perform 4, 331344.
47 Nilsson, M, Stenberg, M, Frid, AH, et al. (2004) Glycemia and insulinemia in healthy subjects after lactose-equivalent meals of milk and other food proteins: the role of plasma amino acids and incretins. Am J Clin Nutr 80, 12461253.
48 Jeukendrup, AE & Wallis, GA (2005) Measurement of substrate oxidation during exercise by means of gas exchange measurements. Int J Sports Med 26, S28S37.
49 Little, JP, Chilibeck, PD, Ciona, D, et al. (2010) Effect of low- and high-glycemic-index meals on metabolism and performance during high-intensity, intermittent exercise. Int J Sports Nutr Exerc Metab 20, 447456.
50 Bennard, P & Doucet, E (2006) Acute effects of exercise timing and breakfast meal glycemic index on exercise-induced fat oxidation. Appl Physiol Nutr Metab 31, 502511.
51 Cheong, SH, McCargar, LJ, Paty, BW, et al. (2009) The first step first bite program: guidance to increase physical activity and daily intake of low-glycemic index foods. J Am Diet Assoc 109, 14111416.
52 Hamzah, S, Higgins, S, Abraham, T, et al. (2009) The effect of glycaemic index of high carbohydrate diets consumed over 5 days on exercise energy metabolism and running capacity in males. J Sports Sci 27, 15451554.
53 Solomon, TP, Haus, JM, Kelly, KR, et al. (2009) Randomized trial on the effects of a 7-d low-glycemic diet and exercise intervention on insulin resistance in older obese humans. Am J Clin Nutr 90, 12221229.
54 Solomon, TP, Haus, JM, Kelly, KR, et al. (2010) A low glycemic index diet combined with exercise reduces insulin resistance, postprandial hyperinsulinemia, and glucose-dependent insulinotropic polypeptide responses in obese, prediabetic humans. Am J Clin Nutr 92, 13591368.
55 Garcia-Roves, P, Huss, JM, Han, D-H, et al. (2007) Raising plasma fatty acid concentration induces increased biogenesis of mitochondria in skeletal muscle. Proc Natl Acad Sci U S A 104, 1070910713.
56 Yeo, WK, Paton, CD, Garnham, AP, et al. (2008) Skeletal muscle adaptation and performance responses to once a day versus twice every second day endurance training regimens. J Appl Physiol 105, 14621470.
57 Morton, JP, Croft, L, Bartlett, JD, et al. (2009) Reduced carbohydrate availability does not modulate training-induced heat shock protein adaptations but does upregulate oxidative enzyme activity in human skeletal muscle. J Appl Physiol 106, 15131521.
58 Burke, LM, Claassen, A, Hawley, JA, et al. (1998) Carbohydrate intake during prolonged cycling minimizes effect of glycemic index of preexercise meal. J Appl Physiol 85, 22202226.
59 Chen, YJ, Wong, SH, Wong, CK, et al. (2008) Effect of preexercise meals with different glycemic indices and loads on metabolic responses and endurance running. Int J Sport Nutr Exerc Metab 18, 281300.
60 Chen, YJ, Wong, SH, Chan, CO, et al. (2009) Effects of glycemic index meal and CHO-electrolyte drink on cytokine response and run performance in endurance athletes. J Sci Med Sport 12, 697703.
61 Wong, SH, Chan, OW, Chen, YJ, et al. (2009) Effect of preexercise glycemic-index meal on running when CHO-electrolyte solution is consumed during exercise. Int J Sport Nutr Exerc Metab 19, 222242.
62 Liedtke, AJ, Nellis, SH, Whitesell, LF, et al. (1982) Metabolic and mechanical effects using l- and d-carnitine in working swine hearts. Am J Physiol 243, H691H697.
63 Murthy, MS & Pande, SV (1987) Malonyl-CoA binding site and the overt carnitine palmitoyltransferase activity reside on the opposite sides of the outer mitochondrial membrane. Proc Natl Acad Sci U S A 84, 378382.
64 McGarry, JD & Brown, NF (1997) The mitochondrial carnitine palmitoyltransferase system. From concept to molecular analysis. Eur J Biochem 244, 114.
65 Stephens, FB, Constantin-Teodosiu, D & Greenhaff, PL (2007) New insights concerning the role of carnitine in the regulation of fuel metabolism in skeletal muscle. J Physiol 581, 431444.
66 Stephens, FB, Constantin-Teodosiu, D, Laithwaite, D, et al. (2006) Insulin stimulates l-carnitine accumulation in human skeletal muscle. FASEB J 20, 377379.
67 Stephens, FB, Constantin-Teodosiu, D, Laithwaite, D, et al. (2006) An acute increase in skeletal muscle carnitine content alters fuel metabolism in resting human skeletal muscle. J Clin Endocrinol Metab 91, 50135018.
68 Stephens, FB, Evans, CE, Constantin-Teodosiu, D, et al. (2007) Carbohydrate ingestion augments l-carnitine retention in humans. J Appl Physiol 102, 10651070.
69 Abramowicz, W & Galloway, S (2005) Effects of acute versus chronic l-carnitine l-tartrate supplementation on metabolic responses to steady state exercise in males and females. Int J Sports Nutr Exerc Metab 15, 386400.
70 Broad, EM, Maughan, RJ & Galloway, SD (2005) Effects of four weeks l-carnitine l-tartrate ingestion on substrate utilization during prolonged exercise. Int J Sport Nutr Exerc Metab 15, 665679.
71 Wall, BT, Stephens, FB, Constantin-Teodosiu, D, et al. (2011) Chronic oral ingestion of l-carnitine and carbohydrate increases muscle carnitine content and alters muscle fuel metabolism during exercise in humans. J Physiol 589, 963973.
72 Burke, LM & Kiens, B (2006) ‘Fat adaptation’ for athletic performance: the nail in the coffin? J Appl Physiol 100, 78.
73 Gannon, MC, Nuttall, JA & Nuttall, FQ (2002) The metabolic response to ingested glycine. Am J Clin Nutr 76, 13021307.
74 Harris, WS, Connor, WE, Alam, N, et al. (1988) Reduction of postprandial triglyceridemia in humans by dietary n-3 fatty acids. J Lipid Res 29, 14511460.
75 Herzberg, GR & Rogerson, M (1989) The effect of dietary fish oil on muscle and adipose tissue lipoprotein lipase. Lipids 24, 351353.
76 Jang, IS, Hwang, DY, Chae, KR, et al. (2003) Role of dietary fat type in the development of adiposity from dietary obesity-susceptible Sprague–Dawley rats. Br J Nutr 89, 429438.
77 Clarke, SD (2000) Polyunsaturated fatty acid regulation of gene transcription: a mechanism to improve energy balance and insulin resistance. Br J Nutr 83, Suppl. 1, S59S66.
78 Price, PT, Nelson, CM & Clarke, SD (2000) Omega-3 polyunsaturated fatty acid regulation of gene expression. Curr Opin Lipidol 11, 37.
79 Baillie, RA, Takada, R, Nakamura, M, et al. (1999) Coordinate induction of peroxisomal acyl-CoA oxidase and UCP-3 by dietary fish oil: a mechanism for decreased body fat deposition. Prostaglandins Leukot Essent Fatty Acids 60, 351356.
80 Clarke, SD (2001) Polyunsaturated fatty acid regulation of gene transcription: a molecular mechanism to improve the metabolic syndrome. J Nutr 131, 11291132.
81 Dangardt, F, Osika, W, Chen, Y, et al. (2010) Omega-3 fatty acid supplementation improves vascular function and reduces inflammation in obese adolescents. Atherosclerosis 212, 580585.
82 Delarue, J, Couet, C, Cohen, R, et al. (1996) Effects of fish oil on metabolic responses to oral fructose and glucose loads in healthy humans. Am J Physiol Endocrinol Metab 270, E353E362.
83 Couet, C, Delarue, J, Ritz, P, et al. (1997) Effect of dietary fish oil on body fat mass and basal fat oxidation in healthy adults. Int J Obes Relat Metab Disord 21, 637643.
84 Smith, BK, Sun, GY, Donahue, OM, et al. (2004) Exercise plus n-3 fatty acids: additive effect on postprandial lipemia. Metabolism 53, 13651371.
85 Hill, AM, Buckley, JD, Murphy, KJ, et al. (2007) Combining fish-oil supplements with regular aerobic exercise improves body composition and cardiovascular disease risk factors. Am J Clin Nutr 85, 12671274.
86 Huffman, DM, Michaelson, JL & Thomas, TR (2004) Chronic supplementation with fish oil increases fat oxidation during exercise in young men. J Exerc Physiol Online 7, 4856.
87 Delarue, J, Labarthe, F & Cohen, R (2003) Fish-oil supplementation reduces stimulation of plasma glucose fluxes during exercise in untrained males. Br J Nutr 90, 777786.
88 Bortolotti, M, Tappy, L & Schneiter, P (2007) Fish oil supplementation does not alter energy efficiency in healthy males. Clin Nutr 26, 225230.
89 Boss, A, Lecoultre, V, Ruffieux, C, et al. (2010) Combined effects of endurance training and dietary unsaturated fatty acids on physical performance, fat oxidation and insulin sensitivity. Br J Nutr 103, 11511159.
90 Schrager, S (2005) Dietary calcium intake and obesity. J Am Board Fam Pract 18, 205210.
91 Dougkas, A, Reynolds, CK, Givens, ID, et al. (2011) Associations between dairy consumption and body weight: a review of the evidence and underlying mechanisms. Nutr Res Rev 15, 124.
92 Christensen, R, Lorenzen, JK, Svith, CR, et al. (2009) Effect of calcium from dairy and dietary supplements on faecal fat excretion: a meta-analysis of randomized controlled trials. Obes Rev 10, 475486.
93 Zemel, MB (2004) Role of calcium and dairy products in energy partitioning and weight management. Am J Clin Nutr 79, 907S912S.
94 Draznin, B (1993) Cytosolic calcium and insulin resistance. Am J Kidney Dis 21, 3238.
95 Sun, X & Zemel, MB (2008) Calcitriol and calcium regulate cytokine production and adipocyte-macrophage cross-talk. J Nutr Biochem 19, 392399.
96 Sun, X & Zemel, MB (2009) Leucine modulation of mitochondrial mass and oxygen consumption in skeletal muscle cells and adipocytes. Nutr Metab (Lond) 6, 26.
97 Soares, MJ & Chan She-Ping-Delfos, WL (2010) Postprandial energy metabolism in the regulation of body weight: is there a mechanistic role for dietary calcium? Nutrients 2, 586598.
98 Maimoun, L & Sultan, C (2009) Effect of physical activity on calcium homeostasis and calciotropic hormones: a review. Calcif Tissue Int 85, 277286.
99 Barry, DW, Hansen, KC, Van Pelt, RE, et al. (2011) Acute calcium ingestion attenuates exercise-induced disruption of calcium homeostasis. Med Sci Sports Exerc 43, 617623.
100 Melanson, EL, Sharp, TA, Schneider, J, et al. (2003) Relation between calcium intake and fat oxidation in adult humans. Int J Obes Relat Metab Disord 27, 196203.
101 Melanson, EL, Donahoo, WT, Dong, F, et al. (2005) Effect of low- and high-calcium dairy-based diets on macronutrient oxidation in humans. Obes Res 13, 21022112.
102 White, KM, Lyle, RM, Flynn, MG, et al. (2006) The acute effects of dairy calcium intake on fat metabolism during exercise and endurance exercise performance. Int J Sport Nutr Exerc Metab 16, 565579.
103 Schutz, Y (2004) Concept of fat balance in human obesity revisited with particular reference to de novo lipogenesis. Int J Obes Relat Metab Disord 28, Suppl. 4, S3S11.
104 Soares, MJ & Chan She Ping-Delfos, W (2008) Second meal effects of dietary calcium and vitamin D. Eur J Clin Nutr 62, 872878.
105 Cummings, NK, James, AP & Soares, MJ (2006) The acute effects of different sources of dietary calcium on postprandial energy metabolism. Br J Nutr 96, 138144.
106 Ping-Delfos, WC & Soares, M (2011) Diet induced thermogenesis, fat oxidation and food intake following sequential meals: influence of calcium and vitamin D. Clin Nutr 30, 376383.
107 Graham, TE, Battram, DS, Dela, F, et al. (2008) Does caffeine alter muscle carbohydrate and fat metabolism during exercise? Appl Physiol Nutr Metab 33, 13111318.
108 Greer, F, Hudson, R, Ross, R, et al. (2001) Caffeine ingestion decreases glucose disposal during a hyperinsulinemic-euglycemic clamp in sedentary humans. Diabetes 50, 23492354.
109 Battram, DS, Shearer, J, Robinson, D, et al. (2004) Caffeine ingestion does not impede the resynthesis of proglycogen and macroglycogen after prolonged exercise and carbohydrate supplementation in humans. J Appl Physiol 96, 943950.
110 Graham, TE (2001) Caffeine, coffee and ephedrine: impact on exercise performance and metabolism. Can J Appl Physiol 26, S103S119.
111 Graham, TE (2001) Caffeine and exercise: metabolism, endurance and performance. Sports Med 31, 785807.
112 Jacobson, TL, Febbraio, MA, Arkinstall, MJ, et al. (2001) Effect of caffeine co-ingested with carbohydrate or fat on metabolism and performance in endurance-trained men. Exp Physiol 86, 137144.
113 Slivka, D, Hailes, W, Cuddy, J, et al. (2008) Caffeine and carbohydrate supplementation during exercise when in negative energy balance: effects on performance, metabolism, and salivary cortisol. Appl Physiol Nutr Metab 33, 10791085.
114 Thong, FS, Derave, W, Kiens, B, et al. (2002) Caffeine-induced impairment of insulin action but not insulin signaling in human skeletal muscle is reduced by exercise. Diabetes 51, 583590.
115 Pedersen, DJ, Lessard, SJ, Coffey, VG, et al. (2008) High rates of muscle glycogen resynthesis after exhaustive exercise when carbohydrate is coingested with caffeine. J Appl Physiol 105, 713.
116 Aschenbach, WG, Sakamoto, K & Goodyear, LJ (2004) 5′ adenosine monophosphate-activated protein kinase, metabolism and exercise. Sports Med 34, 91103.
117 Hursel, R, Viechtbauer, W, Dulloo, AG, et al. (2011) The effects of catechin rich teas and caffeine on energy expenditure and fat oxidation: a meta-analysis. Obes Rev 12, e573e581.


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New perspectives on nutritional interventions to augment lipid utilisation during exercise

  • Javier T. Gonzalez (a1) and Emma J. Stevenson (a1)


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