1.Black, RE, Victora, CG, Walker, SP, et al. (2013) Maternal and child undernutrition and overweight in low-income and middle-income countries. Lancet 382, 427–451.
2.World Health Organization (2016) WHO Guideline: Multiple Micronutrients Powders for Point-of-use Fortification of Foods Consumed by Children 6-23 Months of Age and Children Aged 2-12 Years. Geneva, Switzerland: World Health Organization.
3.De-Regil, LM, Jefferds, MED & Pena-Rosas, JP (2017) Point-of-use fortification of foods with micronutrient powders containing iron in children of preschool and school-age. Cochrane Database Syst Rev, issue 11, CD009666.
4.Salam, RA, Macphail, C, Das, JK, et al. (2013) Effectiveness of Micronutrient Powders (MNP) in women and children. BMC Public Health 13, Suppl. 3, S22.
5.Pasricha, SR & Drakesmith, H (2016) Iron deficiency anemia: problems in diagnosis and prevention at the population level. Hematol Oncol Clin North Am 30, 309–325.
6.Home Fortification Technical Advisory Group (2018) Home fortification activities worldwide. http://www.hftag.org (accessed February 2018). 7.Rivella, S & Giardina, JP (2013) Thalassemia syndromes. In Hematology: Basic Principles and Practice, pp. 505–535 [Hoffman, R, Benz, EJ, Silberstein, L, Heslop, H, Weitz, J and Anastasi, J, editors]. Philadelphia, PA: Elsevier.
8.Vichinsky, E (2007) Hemoglobin E syndromes. Hematology Am Soc Hematol Educ Program 2007, 79–83.
9.Modell, B & Darlison, M (2008) Global epidemiology of haemoglobin disorders and derived service indicators. Bull World Health Organ 86, 480–487.
10.Weatherall, DJ & Clegg, JB (2001) Inherited haemoglobin disorders: an increasing global health problem. Bull World Health Organ 79, 704–712.
11.Fucharoen, S & Winichagoon, P (2000) Clinical and hematologic aspects of hemoglobin E beta-thalassemia. Curr Opin Hematol 7, 106–112.
12.George, J, Yiannakis, M, Main, B, et al. (2012) Genetic hemoglobin disorders, infection, and deficiencies of iron and vitamin A determine anemia in young Cambodian children. J Nutr 142, 781–787.
13.Zimmermann, MB, Fucharoen, S, Winichagoon, P, et al. (2008) Iron metabolism in heterozygotes for hemoglobin E (HbE), alpha-thalassemia 1, or beta-thalassemia and in compound heterozygotes for HbE/beta-thalassemia. Am J Clin Nutr 88, 1026–1031.
14.Jones, E, Pasricha, SR, Allen, A, et al. (2015) Hepcidin is suppressed by erythropoiesis in hemoglobin E beta-thalassemia and beta-thalassemia trait. Blood 125, 873–880.
15.Guimaraes, JS, Cominal, JG, Silva-Pinto, AC, et al. (2015) Altered erythropoiesis and iron metabolism in carriers of thalassemia. Eur J Haematol 94, 511–518.
16.Barffour, M, Hinnouho, G, Kounnavong, S, et al. (2019) Effects of daily zinc, daily multiple micronutrient powder, or therapeutic zinc supplementation for diarrhea prevention on physical growth, anemia, and micronutrient status in rural Laotian children: a randomized controlled trial. J Pediatr 207, 80–89.e2.
17.Barffour, MA, Hinnouho, GM, Kounnavong, S, et al. (2018) Effects of two forms of daily preventive zinc and therapeutic zinc supplementation for diarrhea on diarrhea and acute respiratory tract infections in Laotian children. Curr Dev Nutr 2, OR32-05.
18.Wessells, KR, Brown, KH, Kounnavong, S, et al. (2018) Comparison of two forms of daily preventive zinc supplementation versus therapeutic zinc supplementation for diarrhea on young children’s physical growth and risk of infection: study design and rationale for a randomized controlled trial. BMC Nutr 4, 39.
19.WHO Multicentre Growth Reference Study Group (2006) WHO Child Growth Standards: Length/height-for-age, Weight-for-age, Weight-for-length, Weight-for-height and Body Mass Index-for-age: Methods and Development. Geneva: WHO.
20.European Union, Ministry of Health, MMG, UNICEF (2011) What is SuperKid? Counseling Cards. Ministry of Health. Vientiane: Lao PDR.
21.Coates, J, Swindale, A & Bilinsky, P (2007) Household Food Insecurity Access Scale (HFIAS) for Measurement of Food Access: Indicator Guide. Washington, DC: USAID.
22.de Onis, M, Onyango, AW, Van den Broeck, J, et al. (2004) Measurement and standardization protocols for anthropometry used in the construction of a new international growth reference. Food Nutr Bull 25, S27–S36.
23.Hess, SY, Hinnouho, GM, Barffour, MA, et al. (2018) First field test of an innovative, wider tape to measure mid-upper arm circumference in young Laotian children. Food Nutr Bull 39, 28–38.
24.World Health Organization (2008) Indicators for Assessing Infant and Young Child Feeding Practices. Part I: Definition. Geneva: WHO.
25.World Health Organization (2010) Indicators for Assessing Infant and Young Child Feeding Practices. Part II: Measurement. Geneva: WHO.
26.Erhardt, JG, Estes, JE, Pfeiffer, CM, et al. (2004) Combined measurement of ferritin, soluble transferrin receptor, retinol binding protein, and C-reactive protein by an inexpensive, sensitive, and simple sandwich enzyme-linked immunosorbent assay technique. J Nutr 134, 3127–3132.
27.Yamsri, S, Sanchaisuriya, K, Fucharoen, G, et al. (2010) Prevention of severe thalassemia in northeast Thailand: 16 years of experience at a single university center. Prenat Diagn 30, 540–546.
28.Sae-ung, N, Fucharoen, G, Sanchaisuriya, K, et al. (2007) Alpha(0)-thalassemia and related disorders in northeast Thailand: a molecular and hematological characterization. Acta Haematol 117, 78–82.
29.WHO Multicentre Growth Reference Study Group (2007) WHO Child Growth Standards: Head Circumference-for-age, Arm circumference-for-age, Triceps Skinfold-for-age and Subscapular Skinfold-for-age: Methods and Development. Geneva: WHO.
30.Hess, SY, Barffour, MA & Hinnouho, GM (2018) Lao Zinc Study. Open Science Framework. https://osf.io/5bq9c (accessed December 2018). 31.Namaste, SM, Rohner, F, Huang, J, et al. (2017) Adjusting ferritin concentrations for inflammation: Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) project. Am J Clin Nutr 106, Suppl. 1, 359S–371S.
32.Rohner, F, Namaste, SM, Larson, LM, et al. (2017) Adjusting soluble transferrin receptor concentrations for inflammation: Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) project. Am J Clin Nutr 106, Suppl. 1, 372S–382S.
33.Lynch, S, Pfeiffer, CM, Georgieff, MK, et al. (2018) Biomarkers of Nutrition for Development (BOND)-iron review. J Nutr 148, 1001S–1067S.
34.World Health Organization (2014) Serum Transferrin Receptor Levels for the Assessment of Iron Status and Iron Deficiency in Populations. Vitamin and Mineral Nutrition Information System. Geneva: WHO.
35.Sanchaisuriya, K, Fucharoen, S, Ratanasiri, T, et al. (2007) Effect of the maternal betaE-globin gene on hematologic responses to iron supplementation during pregnancy. Am J Clin Nutr 85, 474–479.
36.Idjradinata, P, Watkins, WE & Pollitt, E (1994) Adverse effect of iron supplementation on weight gain of iron-replete young children. Lancet 343, 1252–1254.
37.Dewey, KG, Domellöf, M, Cohen, RJ, et al. (2002) Iron supplementation affects growth and morbidity of breast-fed infants: results of a randomized trial in Sweden and Honduras. J Nutr 132, 3249–3255.
38.Pasricha, SR, Hayes, E, Kalumba, K, et al. (2013) Effect of daily iron supplementation on health in children aged 4-23 months: a systematic review and meta-analysis of randomised controlled trials. Lancet Glob Health 1, e77–e86.
39.Lonnerdal, B (2017) Excess iron intake as a factor in growth, infections, and development of infants and young children. Am J Clin Nutr 106, 1681S–1687S.
40.Majumdar, I, Paul, P, Talib, VH, et al. (2003) The effect of iron therapy on the growth of iron-replete and iron-deplete children. J Trop Pediatr 49, 84–88.
41.Lind, T, Seswandhana, R, Persson, LA, et al. (2008) Iron supplementation of iron-replete Indonesian infants is associated with reduced weight-for-age. Acta Paediatr 97, 770–775.
42.Vogiatzi, MG, Macklin, EA, Trachtenberg, FL, et al. (2009) Differences in the prevalence of growth, endocrine and vitamin D abnormalities among the various thalassaemia syndromes in North America. Br J Haematol 146, 546–556.
43.Soliman, AT, De Sanctis, V, Yassin, M, et al. (2017) Growth and growth hormone – insulin like growth factor -I (GH-IGF-I) axis in chronic anemias. Acta Biomed 88, 101–111.
44.Hess, SY, Abbeddou, S, Jimenez, EY, et al. (2015) Small-quantity lipid-based nutrient supplements, regardless of their zinc content, increase growth and reduce the prevalence of stunting and wasting in young Burkinabe children: a cluster-randomized trial. PLOS ONE 10, e0122242.
45.Brown, KH, Peerson, JM, Baker, SK, et al. (2009) Preventive zinc supplementation among infants, preschoolers, and older prepubertal children. Food Nutr Bull 30, S12–S40.
46.Mayo-Wilson, E, Junior, JA, Imdad, A, et al. (2014) Zinc supplementation for preventing mortality, morbidity, and growth failure in children aged 6 months to 12 years of age. Cochrane Database Syst Rev, issue 5, CD009384.
47.Yakoob, MY, Theodoratou, E, Jabeen, A, et al. (2011) Preventive zinc supplementation in developing countries: impact on mortality and morbidity due to diarrhea, pneumonia and malaria. BMC Public Health 11, Suppl. 3, S23.
48.Mayo-Wilson, E, Imdad, A, Junior, J, et al. (2014) Preventive zinc supplementation for children, and the effect of additional iron: a systematic review and meta-analysis. BMJ Open 4, e004647.
49.Soofi, S, Cousens, S, Iqbal, SP, et al. (2013) Effect of provision of daily zinc and iron with several micronutrients on growth and morbidity among young children in Pakistan: a cluster-randomised trial. Lancet 382, 29–40.
50.Sampaio, DL, Mattos, AP, Ribeiro, TC, et al. (2013) Zinc and other micronutrients supplementation through the use of sprinkles: impact on the occurrence of diarrhea and respiratory infections in institutionalized children. J Pediatr (Rio J) 89, 286–293.
51.Osei, AK, Rosenberg, IH, Houser, RF, et al. (2010) Community-level micronutrient fortification of school lunch meals improved vitamin A, folate, and iron status of schoolchildren in Himalayan villages of India. J Nutr 140, 1146–1154.
52.Inayati, DA, Scherbaum, V, Purwestri, RC, et al. (2012) Combined intensive nutrition education and micronutrient powder supplementation improved nutritional status of mildly wasted children on Nias Island, Indonesia. Asia Pac J Clin Nutr 21, 361–373.
53.Giovannini, M, Sala, D, Usuelli, M, et al. (2006) Double-blind, placebo-controlled trial comparing effects of supplementation with two different combinations of micronutrients delivered as sprinkles on growth, anemia, and iron deficiency in Cambodian infants. J Pediatr Gastroenterol Nutr 42, 306–312.
54.Jaeggi, T, Kortman, GA, Moretti, D, et al. (2014) Iron fortification adversely affects the gut microbiome, increases pathogen abundance and induces intestinal inflammation in Kenyan infants. Gut.
55.Paganini, D & Zimmermann, MB (2017) The effects of iron fortification and supplementation on the gut microbiome and diarrhea in infants and children: a review. Am J Clin Nutr 106, 1688S–1693S.
