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The hypolipidaemic effect of inulin: when animal studies help to approach the human problem

Published online by Cambridge University Press:  09 March 2007

N. M. Delzenne
N. M. Delzenne
Affiliation:
Pharmacokinetics Metabolism, Nutrition and Toxicology Unit 7369, School of Pharmacy, Université Catholique de Louvain, B-1200 Brussels, Belgium
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Abstract

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Type
Invited commentary
Information
British Journal of Nutrition , Volume 82 , Issue 1 , July 1999 , pp. 3 - 4
Copyright
Copyright © The Nutrition Society 1999

References

Aghelli, N, Kabir, M, Berni-Canani, S, Petitjeran, E, Boussairi, A, Luo, J, Bornet, F, Slama, G & Rizkalla, SW (1998) Plasma lipids and fatty acid synthase activity are regulated by short-chain fructo-oligosaccharides in sucrose-fed insulin-resistant rats. Journal of Nutrition 128, 1283–1288.CrossRefGoogle Scholar
Alles, MS, de Roos, NM, Bakx, JC, van de Lisdonk, E, Zock, PL & Hautvast, JGAJ (1999) Consumption of fructooligosaccharides does not favorably affect blood glucose and serum lipid concentrations in patients with type 2 diabetes. American Journal of Clinical Nutrition 69, 64–69.CrossRefGoogle Scholar
Delzenne, N & Kok, N (1998) Effect of non-digestible fermentable carbohydrates on hepatic fatty acid metabolism. Biochemical Society Transactions 26, 1997–1999.CrossRefGoogle ScholarPubMed
Demigné, C, Morand, C, Levrat, MA & Besson, C (1995) Effect of propionate on fatty acid and cholesterol synthesis and acetate metabolism in isolated rat hepatocytes. British Journal of Nutrition 74, 209–219.CrossRefGoogle ScholarPubMed
Jackson, KG, Taylor, GRJ, Clohessy, AM & Williams, CM (1999) The effect of the daily intake of inulin on fasting lipid, insulin and glucose concentrations in middle-aged men and women. British Journal of Nutrition 82, 23–30.CrossRefGoogle ScholarPubMed
Knapper, JM, Puddicombe, SM, Morgan, LM & Fletcher, JM (1995) Investigations into the actions of glucose-dependent insulinotropic polypeptide and glucagon-like peptide 1 (7-36 amide on lipoprotein lipase activity in explants of rat adipose tissue. Journal of Nutrition 125, 183–188.Google ScholarPubMed
Kok, N, Morgan, LM, Williams, CM, Roberfroid, MB, Thissen, JP & Delzenne, NM (1998) Insulin, glucagon-like peptide 1, glucose-dependent insulinotropic polypeptide and insulin-like growth factor I as putative mediators of the hypolipidemic effect of oligofructose in rats. Journal of Nutrition 128, 1099–1103.CrossRefGoogle ScholarPubMed
Kok, N, Taper, H & Delzenne, NM (1998) Oligofructose modulates lipid metabolism alterations induced by a fat-rich diet in rats. Journal of Applied Toxicology 18, 47–53.3.0.CO;2-S>CrossRefGoogle ScholarPubMed
Levrat, MA, Favier, ML, Moundras, C Rémésy C Demigné C & Morand, C (1994) Role of dietary propionic acid and bile acid excretion in the hypocholesterolemic effects of oligosaccharides in rats. Journal of Nutrition 124, 531–538.CrossRefGoogle ScholarPubMed
Moundras, C, Behr, SR, Demigné, C, Mazur, A & Rémésy, C (1994) Fermentable carbohydrates that enhance fecal bile acid excretion lower plasma cholesterol and apolipoprotein E-rich HDL in rats. Journal of Nutrition 124, 2179–2188.CrossRefGoogle ScholarPubMed
Roberfroid, MB & Delzenne, NM (1998) Dietary fructans. Annual Review of Nutrition 18, 117–143.CrossRefGoogle ScholarPubMed
Trautwein, EA, Rieckhoff, D & Erbersdobler, HF (1998) Dietary inulin lowers plasma cholesterol and triacylglycerol and alters biliary bile acid profile in hamster. Journal of Nutrition 128, 1937–1943.CrossRefGoogle Scholar