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From early nutrition and later development...to underlying mechanisms and optimal health

Published online by Cambridge University Press:  09 August 2018

M. J. Dauncey*
Affiliation:
Laboratory of Nutrient-Cell-Gene Interactions, Department of Cellular Physiology, The Babraham Institute, Cambridge CB2 4AT
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‘Life is a country that the old have seen, and lived in. Those who have to travel through it can only learn the way from them.’

Joseph Joubert, 1842

This quotation is perhaps especially appropriate when considering the extensive contributions made by Professor McCance and Dr Widdowson to the field of early nutrition and later development. A detailed knowledge of their work in this area is of undoubted value both in interpreting many recent findings and in the design of new investigations. The first part of this paper presents a brief overview of some of their most significant studies. Their implications at both the fundamental and applied levels are then discussed, especially in relation to the role of nutrition in health and disease. Finally, potential mechanisms by which development may be modified by early nutrition are considered.

Type
Research Article
Copyright
Copyright © The Authors 1997

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