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Effects of mate tea consumption on muscle strength and oxidative stress markers after eccentric exercise

  • Vilma Pereira Panza (a1), Fernando Diefenthaeler (a2), Aline Cavalheiro Tamborindeguy (a2), Carolina de Quadros Camargo (a1) (a3), Bruno Monteiro de Moura (a2), Henver Simionato Brunetta (a3), Raphael Luiz Sakugawa (a2), Marina Vieira de Oliveira (a4), Emiliana de Oliveira Puel (a4), Everson Araújo Nunes (a1) (a3) and Edson Luiz da Silva (a1) (a4)...


Dietary phytochemical supplementation may improve muscle recovery from exercise. In this study, we investigated the effect of mate tea (MT) consumption – a phenol-rich beverage – on muscle strength and oxidative stress biomarkers after eccentric exercise. In a randomised, cross-over design, twelve men were assigned to drink either MT or water (control; CON) for 11 d. On the 8th day, subjects performed three sets of twenty maximal eccentric elbow flexion exercises. Maximal isometric elbow flexion force was measured before and at 0, 24, 48 and 72 h after exercise. Blood samples were obtained before and at 24, 48 and 72 h after exercise and analysed for total phenolics, GSH, GSSG, GSH:GSSG ratio and lipid hydroperoxides (LOOH). After eccentric exercise, muscle strength was significantly reduced over time, regardless of treatments. However, MT improved the rate of strength recovery by 8·6 % on the 1st day after exercise (P<0·05). Plasma concentration of total phenolic compounds was higher in MT than in CON at all time points (P<0·05) but decreased significantly at 72 h after exercise in both trials (P<0·05). Blood levels of GSH were significantly decreased at 48 and 72 h after exercise in CON (P<0·05) but did not change over time in MT. No significant changes were observed for GSSG, GSH:GSSG ratio and LOOH levels. MT intake did not influence muscle strength at all time points assessed but hastened the strength recovery over 24 h after exercise. MT also favoured the concentration of blood antioxidant compounds.

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Corresponding author

* Corresponding author: E. L. d. Silva, email


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1. Allen, DG (2001) Eccentric muscle damage: mechanisms of early reduction of force. Acta Physiol Scand 171, 311319.
2 Paulsen, G, Mikkelsen, UR, Raastad, T, et al. (2012) Leucocytes, cytokines and satellite cells: what role do they play in muscle damage and regeneration following eccentric exercise? Exerc Immunol Rev 18, 4297.
3. Faulkner, JA, Brooks, SV & Opiteck, JA (1993) Injury to skeletal muscle fibers during contractions: conditions of occurrence and prevention. Phys Ther 73, 911921.
4. McLeay, Y, Barnes, MJ, Mundel, T, et al. (2012) Effect of New Zealand blueberry consumption on recovery from eccentric exercise-induced muscle damage. J Int Soc Sports Nutr 9, 19.
5. Zerba, E, Komorowski, TE & Faulkner, JA (1990) Free radical injury to skeletal muscles of young, adult, and old mice. Am J Physiol 258, 429435.
6. Lapointe, BM, Frenette, J & Côté, CH (2002) Lengthening contraction-induced inflammation is linked to secondary damage but devoid of neutrophil invasion. J Appl Physiol 92, 19952004.
7. Toumi, H, F’guyer, S & Best, TM (2006) The role of neutrophils in injury and repair following muscle stretch. J Anat 208, 459470.
8. Pizza, FX, Peterson, JM, Baas, JH, et al. (2005) Neutrophils contribute to muscle injury and impair its resolution after lengthening contractions in mice. J Physiol 562, 899913.
9. Trombold, JR, Barnes, JN, Critchley, L, et al. (2010) Ellagitannin consumption improves strength recovery 2–3 d after eccentric exercise. Med Sci Sports Exerc 42, 493498.
10. Machin, DR, Christmas, KM, Chou, TH, et al. (2014) Effects of differing dosages of pomegranate juice supplementation after eccentric exercise. Physiol J 2014, 7.
11. Trombold, JR, Reinfeld, AS, Casler, JR, et al. (2011) The effect of pomegranate juice supplementation on strength and soreness after eccentric exercise. J Strength Cond Res 25, 17821788.
12. Connolly, DA, McHugh, MP, Padilla-Zakour, OI, et al. (2006) Efficacy of a tart cherry juice blend in preventing the symptoms of muscle damage. Br J Sports Med 40, 679683.
13. Bracesco, N, Sanchez, AG, Contreras, V, et al. (2011) Recent advances on Ilex paraguariensis research: minireview. J Ethnopharmacol 136, 378384.
14. Matsumoto, RL, Bastos, DH, Mendonça, S, et al. (2009) Effects of mate tea (Ilex paraguariensis) ingestion on mRNA expression of antioxidant enzymes, lipid peroxidation, and total antioxidant status in healthy young women. J Agric Food Chem 57, 17751780.
15. Fernandes, ES, Machado, MO, Becker, AM, et al. (2012) Yerba mate (Ilex paraguariensis) enhances the gene modulation and activity of paraoxonase-2: in vitro and in vivo studies. Nutrition 28, 11571164.
16. Klein, GA, Stefanuto, A, Boaventura, BC, et al. (2011) Mate tea (Ilex paraguariensis) improves glycemic and lipid profiles of type 2 diabetes and pre-diabetes individuals: a pilot study. J Am Coll Nutr 30, 320332.
17. Alkhatib, A (2014) Yerba Maté (Illex paraguariensis) ingestion augments fat oxidation and energy expenditure during exercise at various submaximal intensities. Nutr Metab (Lond) 11, 42.
18. Morgan-Martins, MA, Silva, VS, Licks, S, et al. (2013) Ilex paraguariensis St. Hill (yerba mate) improves the metabolic profile of and protects against oxidative stress in exercised and non-exercised rats. Int J Pharm Bio Sci 4, 13031311.
19. Singleton, VL, Orthofer, R & Lamuela-Raventos, RM (1999) Analysis of total phenols and other oxidation substrates and antioxidants by means of Folin-Ciocalteu reagent. Methods Enzymol 299, 152178.
20. Strassmann, BB, Vieira, AR, Pedrotti, EL, et al. (2008) Quantitation of methylxanthinic alkaloids and phenolic compounds in mate (Ilex paraguariensis) and their effects on blood vessel formation in chick embryos. J Agric Food Chem 56, 83488353.
21. Gnoatto, SCB, Schenkel, EP & Bassani, VL (2005) HPLC method to assay total saponins in Ilex paraguariensis aqueous extract. J Braz Chem Soc 16, 723726.
22. Fan, JP & He, CH (2006) Simultaneous quantification of three major bioactive triterpene acids in the leaves of Diospyros kaki by high performance liquid chromatography method. J Pharm Biomed Anal 41, 950956.
23. Serafini, M, Maiani, G & Ferro-Luzzi, A (1998) Alcohol-free red wine enhances plasma antioxidant capacity in humans. J Nutr 128, 10031007.
24. Giustarini, D, Dalle-Donne, I, Milzani, A, et al. (2013) Analysis of GSH and GSSG after derivatization with N-ethylmaleimide. Nat Protoc 8, 16601669.
25. Nourooz-Zadeh, J, Tajaddini-Sarmadi, J & Wolff, SP (1994) Measurement of plasma hydroperoxide concentrations by the ferrous oxidation xylenol orange assay in conjunction with triphenylphosphine. Anal Biochem 220, 403409.
26. Cohen, J (1993) A power primer. Psychol Bull 112, 155159.
27. Dunlap, WP, Cortina, JM, Vaslow, JB, et al. (1996) Meta-analysis of experiments with matched groups or repeated measures designs. Psychol Methods 1, 170177.
28. Romano, J, Kromrey, JD, Coraggio, J, et al. (2006) Exploring methods for evaluating group differences on the NSSE and other surveys: are the t-test and Cohen’s d indices the most appropriate choices? (accessed December 2014).
29. Faul, F, Erdfelder, E, Lang, A-G & Buchner, A (2007)) G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behav Res Methods 39, 175191.
30. MacBeth, G, Razumiejczyk, E & Ldesma, RD (2011) Cliff ’s Delta Calculator: a non-parametric effect size program for two groups of observations. Univ Psychol 10, 545555.
31. Borges, MC, Vinolo, MA, Nakajima, K, et al. (2013) The effect of mate tea (Ilex paraguariensis) on metabolic and inflammatory parameters in high-fat diet-fed Wistar rats. Int J Food Sci Nutr 64, 561569.
32. Lanzetti, M, Bezerra, FS, Romana-Souza, B, et al. (2008) Mate tea reduced acute lung inflammation in mice exposed to cigarette smoke. Nutrition 24, 375381.
33. MacIntyre, DL, Reid, WD, Lyster, DM, et al. (1996) Presence of WBC, decreased strength, and delayed soreness in muscle after eccentric exercise. J Appl Physiol 80, 10061013.
34. Fielding, RA, Manfredi, TJ, Ding, W, et al. (1993) Acute phase response in exercise. III. Neutrophil and IL-1 beta accumulation in skeletal muscle. Am J Physiol 265, 166172.
35. Tidball, JG & Villalta, SA (2010) Regulatory interactions between muscle and the immune system during muscle regeneration. Am J Physiol Regul Integr Comp Physiol 298, 11731187.
36. Brickson, S, Hollander, J, Corr, DT, et al. (2001) Oxidant production and immune response after stretch injury in skeletal muscle. Med Sci Sports Exerc 33, 20102015.
37. Goldfarb, AH, Garten, RS, Cho, C, et al. (2011) Effects of a fruit/berry/vegetable supplement on muscle function and oxidative stress. Med Sci Sports Exerc 43, 501508.
38. Paschalis, V, Nikolaidis, MG, Fatouros, IG, et al. (2007) Uniform and prolonged changes in blood oxidative stress after muscle-damaging exercise. In Vivo 21, 877883.
39. Nikolaidis, MG, Paschalis, V, Giakas, G, et al. (2007) Decreased blood oxidative stress after repeated muscle-damaging exercise. Med Sci Sports Exerc 39, 10801089.
40. Lee, J, Goldfarb, AH, Rescino, MH, et al. (2002) Eccentric exercise effect on blood oxidative-stress markers and delayed onset of muscle soreness. Med Sci Sports Exerc 34, 443448.
41. Bastos, DH, Saldanha, LA, Catharino, RR, et al. (2007) Phenolic antioxidants identified by ESI-MS from Yerba maté (Ilex paraguariensis) and green tea (Camellia sinensis) extracts. Molecules 12, 423432.
42. Filip, R, López, P, Giberti, G, et al. (2001) Phenolic compounds in seven South American Ilex species. Fitoterapia 72, 774778.
43. Rice-Evans, CA, Miller, NJ & Paganga, G (1996) Structure-antioxidant activity relationships of flavonoids and phenolic acids. Free Radic Biol Med 20, 933956.
44. Childs, A, Jacobs, C, Kaminski, T, et al. (2001) Supplementation with vitamin C and N-acetyl-cysteine increases oxidative stress in humans after an acute muscle injury induced by eccentric exercise. Free Radic Biol Med 31, 745753.



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