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Dietary fibre and the pruritus of cholestatic jaundice
Published online by Cambridge University Press: 09 March 2007
Abstract
1. In a double reversal experiment, diets containing either a normal or a large amount of lignin fibre were given to four patients with pruritus due to a liver disease.
2. Neither an improvement in symptoms nor a decrease in serum bile acid levels was found. The dose of fibre may have been insufficient, changes in intraluminal pH may have impaired adsorption of bile acids, or, less likely, the concentration of bile acids in the intestine may have been too low.
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