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Dependence of thyroxine utilization rate on dietary composition

Published online by Cambridge University Press:  09 March 2007

D. L. Ingram  and
S. E. Evans
D. L. Ingram
Affiliation:
ARC Institute of Animal Physiology, Babraham, Cambridge, and Department of Clinical Chemistry, Queen Elizabeth Medical Centre, Edgbaston, Birmingham
S. E. Evans
Affiliation:
ARC Institute of Animal Physiology, Babraham, Cambridge, and Department of Clinical Chemistry, Queen Elizabeth Medical Centre, Edgbaston, Birmingham
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Abstract

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1. The rate of utilization (k) of labelled thyroxine increased when energy intake, given as standard pig meal, was doubled from 20 to 40 g/kg body-weight per d. When the bulk of food was increased, but not its energy content, the value of k did not change. Ambient temperature was constant throughout the experiment.

2. Groups of pigs were given pig meal at 20 g/kg body-weight, 40 g/kg body-weight or 20 g/kg body-weight plus a supplement. The supplement was of equivalent energy content to 20 g pig meal/kg body-weight and consisted of coconut (high-fat), fish meal (high-protein) or glucose. The values of k were similar on diets (g/kg body-weight) of 40 pig meal, 20 pig meal plus coconut, and 20 pig meal plus fish meal. When the supplement was glucose however the values of k were similar to that for 20 g pig meal/kg body-weight.

The plasma concentrations of T4, and triiodothyronine were not affected by eating a meal, or by changing the energy intake presented as pig meal. A comparison between pigs given 20 g pig meal/kg body-weight plus supplements of bran, coconut, fish meal or glucose revealed differences in the concentration of both hormones. When food was withdrawn for 5 d the concentrations of both hormones declined.

Type
Papers on General Nutrition
Information
British Journal of Nutrition , Volume 43 , Issue 3 , May 1980 , pp. 525 - 531
Copyright
Copyright © The Nutrition Society 1980

References

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