Mahan, DC & Shields, RG Jr (1998) Macro- and micromineral composition of pigs from birth to 145 kg of body weight. J Anim Sci
Underwood, EJ & Suttle, NF (1999) The Mineral Nutrition of Livestock, 3rd ed.
Wallingford: CABI Publishing.
Poulsen, HD (1995) Zinc oxide for weanling piglets. Acta Agric Scand Sect A: Anim Sci
Carlson, MS, Hill, GM & Link, JE (1999) Early- and traditionally weaned nursery pigs benefit from phase-feeding pharmacological concentrations of zinc oxide: effect on metallothionein and mineral concentrations. J Anim Sci
Hill, GM, Cromwell, GL, Crenshaw, TD, et al. (2000) Growth promotion effects and plasma changes from feeding high dietary concentrations of zinc and copper to weanling pigs (regional study). J Anim Sci
Case, CL & Carlson, MS (2001) Effect of feeding nursery pigs organic or inorganic sources of zinc on nutrient balance. J Anim Sci
79, Suppl. 1, 51 Abstr.
Pluske, JR, Hansen, CF, Payne, HG, et al. (2007) Gut health in the pig. In Manipulating Pig Production XI, pp. 147–158 [Paterson, JE and Barker, JA, editors]. Werribee, VIC: Australasian Pig Science Association.
Poulsen, HD & Larsen, T (1995) Zinc excretion and retention in growing pigs fed increasing levels of zinc oxide. Livest Prod Sci
Case, CL & Carlson, MS (2002) Effect of feeding organic and inorganic sources of additional zinc on growth performance and zinc balance in nursery pigs. J Anim Sci
Ward, TL, Asche, GA, Louis, GF, et al. (1996) Zinc-methionine improves growth performance of starter pigs. J Anim Sci
74, Suppl. 1, 182 Abstr.
Wang, Y, Tang, JW, Ma, WQ, et al. (2010) Dietary zinc glycine chelate on growth performance, tissue mineral concentrations, and serum enzyme activity in weanling piglets. Biol Trace Elem Res
Schell, TC & Kornegay, ET (1996) Zinc concentrations in tissues and performance of weanling pigs fed pharmacological levels of zinc from ZnO, Zn-Met, Zn-Lys, or ZnSO4
. J Anim Sci
Crane, JK, Naeher, TM, Shulgina, I, et al. (2007) Effect of zinc in enteropathogenic Escherichia coli infection. Infect Immun
Bhutta, ZA, Darmstadt, GL, Hasan, BS, et al. (2005) Community-based interventions for improving perinatal and neonatal health outcomes in developing countries: a review of the evidence. Pediatrics
Gielda, LM & DiRita, VJ (2012) Zinc competition among the intestinal microbiota. MBio
Zhang, B & Guo, Y (2009) Supplemental zinc reduced intestinal permeability by enhancing occluding and zonula occludens protein 1 (ZO-1) expression in weaning piglets. Br J Nutr
Mcafee, BJ, Gould, WD, Nadeau, JC, et al. (2001) Biosorption of metal ions using chitosan, chitin, and biomass of Rhizopus oryzae
. Separ Sci Technol
Wang, XH, Du, Y & Liu, H (2004) Preparation, characterization and antimicrobial activity of chitosan-Zn complex. Carbohyd Polym
Xie, ZJ, Zhu, YM, Han, XY, et al. (2010) Effect of chitosan-zinc on growth performance, serum hormone and biochemical indices of weaning piglets. Chin J Anim Nutr
NRC (1998) Nutrient Requirements of Swine, 10th rev. ed.
Washington, DC: National Academy Press.
Goodlad, RA, Levi, S, Lee, CY, et al. (1991) Morphometry and cell proliferation in endoscopic biopsies: evaluation of a technique. Gastroenterology
Gavrieli, Y, Sherman, Y & Ren Sasson, SA (1993) Identification of programmed cell death in situ via specific labeling of nuclear fragmentation. J Cell Biol
Li, JY, Lu, Y, Hu, S, et al. (2002) Preventive effect of glutamine on intestinal barrier dysfunction induced by severe trauma. World J Gastroenterol
Brandt, RB, Siegel, SA, Waters, MG, et al. (1980) Spectrophotometric assay for d-( − )-lactate in plasma. Anal Biochem
Hurley, JC, Tosolini, FA & Louis, WJ (1991) Quantitative Limulus lysate assay for endotoxin and the effect of plasma. J Clin Pathol
Van Beers-Schreuers, HM, Nabuurs, MJ, Kalsbeek-van der Valk, HJ, et al. (1998) Weaning and the weaning diet influence the villous height and crypt depth in the small intestine of pigs and alter the concentrations of short-chain acids in the large intestine and blood. J Nutr
Madec, F, Bridoux, N, Bounaix, S, et al. (2000) Experimental models of porcine post-weaning colibacillosis and their relationship to post-weaning diarrhoea and digestive disorders as encountered in the field. Vet Microbiol
Boudry, G, Guerin, S & Malbert, H (2004) Effect of an abrupt switch from a milk-based to a fibre-based diet on gastric emptying rates in pigs: difference between origins of fibre. Br J Nutr
Smith, F, Clark, JE, Overman, BL, et al. (2010) Early weaning stress impairs development of mucosal barrier function in the porcine intestine. Am J Physiol Gastrointest Liver Physiol
Moeser, AJ, Borst, LB, Overman, BL, et al. (2012) Defects in small intestinal epithelial barrier function and morphology associated with peri-weaning failure to thrive syndrome (PFTS) in swine. Res Vet Sci
Castillo, M, Martín-Orúe, SM, Nofrarías, M, et al. (2007) Changes in caecal microbiota and mucosal morphology of weaned pigs. Vet Microbiol
Prasad, AS, Bao, B, Beck, FWJ, et al. (2002) Zinc enhances the expression of interleukin-2 and interleukin-2 receptors in HUT-78 cells by way of NF-κB activation. J Lab Clin Med
Sturniolo, GC, Di Leo, V, Ferronato, A, et al. (2001) Zinc supplementation tightens leaky gut in Crohn's disease. Inflamm Bowel Dis
Wu, G, Meier, SA & Knabe, DA (1996) Dietary glutamine supplementation prevents jejunal atrophy in weaned pigs. J Nutr
Murray, MJ, Barbose, JJ & Cobb, CF (1993) Serum d( − )-lactate levels as a predictor of acute intestinal ischemia in a rat model. J Surg Res
Hu, CH, Qian, ZC, Xu, HP, et al. (2009) Effects of high Zn on intestinal barrier and expression of tight junction protein in early-weaned piglets. Chin J Anim Vet Sci
Hedemann, MS, Højsgaard, S & Jensen, BB (2003) Small intestinal morphology and activity of intestinal peptidases in piglets around weaning. J Anim Physiol Anim Nutr
Carlson, MS, Hoover, SL, Hill, GM, et al. (1998) Effect of pharmacological zinc on intestinal metallothionein concentration and morphology in the nursery pig. J Anim Sci
76, Suppl. 1, 57 Abstr.
Li, BT, van Kessel, AG, Caine, WR, et al. (2001) Small intestinal morphology and bacterial populations in ileal digesta and feces of newly weaned pigs receiving a high dietary level of zinc oxide. Can J Anim Sci
Salgueiro, MJ, Zubillaga, M, Lysionek, A, et al. (2000) Zinc as an essential micronutrient: a review. Nutr Res
Scott, ME & Koski, KG (2000) Zinc deficiency impairs immune responses against parasitic nematode infections at intestinal and systemic sites. J Nutr
Ushida, K, Kameue, C, Tsukahara, T, et al. (2008) Decreasing traits of fecal immunoglobulin A in neonatal and weaning piglets. J Vet Med Sci
Snoeck, V, Peters, IR & Cox, E (2006) The IgA system: a comparison of structure and function in different species. Vet Res
Mantis, NJ, Rol, N & Corthésy, B (2011) Secretory IgA's complex roles in immunity and mucosal homeostasis in the gut. Mucosal Immunol
Prasad, AS (2008) Clinical, immunological, anti-inflammatory and antioxidant roles of zinc. Exp Gerontol