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Blood cells as functional markers of antioxidant vitamin status

Published online by Cambridge University Press:  08 March 2007

Josep Tur-Marí*
Affiliation:
Laboratory of Physical Activity Sciences, Community Nutrition and Oxidative Stress Research Group (IUNICS), University of the Balearic Islands, Guillem Colom Building, Campus, E-07122 Palma de Mallorca, Spain
Antoni Sureda
Affiliation:
Laboratory of Physical Activity Sciences, Community Nutrition and Oxidative Stress Research Group (IUNICS), University of the Balearic Islands, Guillem Colom Building, Campus, E-07122 Palma de Mallorca, Spain
Antoni Pons
Affiliation:
Laboratory of Physical Activity Sciences, Community Nutrition and Oxidative Stress Research Group (IUNICS), University of the Balearic Islands, Guillem Colom Building, Campus, E-07122 Palma de Mallorca, Spain
*
*Corresponding author: Dr J. Tur-Marí, fax +34 971 173184, email pep.tur@uib.es
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Abstract

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Antioxidants have shown beneficial effects in several biological systems, in which they were able to prevent oxidative stress-associated damage. Vitamins C and E are key antioxidants in man. Dietary intake cannot accurately reflect plasma vitamin levels. However, the plasma levels of antioxidant vitamins could also reflect the acute assimilation of these vitamins. It has been pointed out that antioxidant vitamin blood contents reach a saturation level by intake of dietary supplements. Antioxidant vitamin plasma levels are the parameter most used to determine antioxidant status. However, the vitamin plasma levels may not reflect the nutritional status of vitamins. It has been pointed out that the vitamin E in adipose tissue can be used as a measure of vitamin E status. To determinate antioxidant vitamin contents in lymphocytes and neutrophils after exercise is a useful tool to assess the functional status of antioxidant vitamins.

Type
Research Article
Copyright
Copyright © The Nutrition Society 2006

References

Aguiló, A, Tauler, P, Fuentespina, E, Tur, JA, Córdova, A & Pons, A (2005) Antioxidant response to oxidative stress induced by exhaustive exercise. Physiol Behav 84,   17.CrossRefGoogle ScholarPubMed
Aguiló, A, Tauler, P, Guix, P, Villa, G, Córdova, A, Tur, JA & Pons, A (2003) Effect of exercise intensity and training on antioxidants and cholesterol profile in cyclists. J Nutr Biochem 14, 319325.CrossRefGoogle ScholarPubMed
Cases, N, Aguiló, A, Tauler, P, Sureda, A, Llompart, I, Pons, A & Tur, JA (2005) Differential response of plasma and immune cell's vitamin E levels to physical activity and antioxidant vitamin supplementation. Eur J Clin Nutr 59, 781788.CrossRefGoogle ScholarPubMed
Cases, N, Sureda, A, Tauler, P, Aguiló, A, Villa, G, Córdova, A, Pons, A & Tur, JA (2003) Vitamin E recommended daily intake is not enough to avoid the oxidative stress induced by intense exercise. Proceedings of the Meeting ‘Oxidants and Antioxidants in Biology’, A Joint Meeting of the Oxygen Club of California, The University of Cádiz (Spain), and The Free Radicals Spanish Group. El Puerto de Santa María, Cádiz.Google Scholar
Feinberg, M, Favier, C, Ireland-Ripert, J (1995) Répertoire Géneral Des Aliments. París: Tec & Doc Lavoisier.Google Scholar
Food and Nutrition BoardFood and Nutrition Board (2000) Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Washington, DC: National Academy Press.Google Scholar
Hamilton, IM, Gilmore, WS, Benzie, IF, Mulholland, CW & Strain, JJ (2000) Interactions between vitamins C and E in human subjects. Br J Nutr 84, 261267.CrossRefGoogle Scholar
Horwitt, MK (2001) Critique of the requirement for vitamin E. Am J Clin Nutr 73, 10031005.CrossRefGoogle ScholarPubMed
Iuliano, L, Micheletta, F, Maranghi, M, Frati, G, Diczfalusy, U & Violi, F (2001) Bioavailability of vitamin E as a function of food intake in healthy subjects: effects on plasma peroxide-scavenging activity and cholesterol-oxidation products. Arterioscler Thromb Vasc Biol 21, E34E37.CrossRefGoogle ScholarPubMed
Kayden, HJ, Hatam, LJ & Traber, MG (1983) The measurement of nanograms of tocopherol from needle aspiration biopsies of adipose tissue: normal and abetalipoproteinemic subjects. J Lipid Res 24, 652656.CrossRefGoogle ScholarPubMed
Leonard, SW, Good, CK, Gugger, ET & Traber, MG (2004) Vitamin E bioavailability from fortified breakfast cereal is greater than that from encapsulated supplements. Am J Clin Nutr 79, 8692.CrossRefGoogle ScholarPubMed
Ji, LL (1999) Antioxidants and oxidative stress in exercise. Proc Soc Exp Biol Med 222, 283292.CrossRefGoogle ScholarPubMed
Mataix, J, Mañas, M, Llopis, J, Martínez, de, Victoria, E, Juan, J & Obregón, A (2003) Spanish Food Composition Tables. 4th ed. Granada: INTA, University of Granada (in Spanish).Google Scholar
Moreiras, O, Carvajal, A, Cabrera, L & Cuadrado, C (2003) Food Composition Tables. 7th ed. Madrid: Piramide (in Spanish).Google Scholar
Morrisey, PA & Sheehy, PJA (1999) Optimal nutrition: vitamin E. Proc Nutr Soc 58, 459468.CrossRefGoogle Scholar
Packer, L, Obermüller-Jevic, UC (2002) Vitamin E in disease prevention and therapy: future perspectives. In The Antioxidant Vitamins C and E, pp.255288 [Packer, L, Traber, MG, Kraemer, K and Frei, B, editors]. Champaign, IL: AOCS Press.Google Scholar
Padayatty, SJ, Katz, A & Wang, Y et al. (2003) Vitamin C as an antioxidant: evaluation of its role in disease prevention. Am J Coll Nutr 22, 1835.CrossRefGoogle ScholarPubMed
Palazzetti, S, Rousseau, AS, Richard, MJ, Favier, A & Margaritis, I (2004) Antioxidant supplementation preserves antioxidant response in physical training and low antioxidant intake. Br J Nutr 91, 91100.CrossRefGoogle ScholarPubMed
Pons, A, Tur, JA, Tauler, P, Aguiló, A, Cases, N & Piña, A (2002) Isotonic energy drink and procedure for obtaining it. PCT/IB02/02503.Google Scholar
Rokitzki, L, Logemann, E, Huber, G, Keck, E & Keul, J (1994) Alpha-tocopherol supplementation in racing cyclist during extreme endurance training. Int J Sport Nutr 4, 253264.CrossRefGoogle ScholarPubMed
Sureda, A, Batle, JM, Tauler, P, Aguiló, A, Cases, N, Tur, JA & Pons, A (2004) Hypoxia/reoxygenation and vitamin C intake influence NO synthesis and antioxidant defenses of neutrophils. Free Radic Biol Med 37, 17441755.CrossRefGoogle ScholarPubMed
Traber, MG (2001) Vitamin E: too much or not enough ? Am J Clin Nutr 73, 997998.CrossRefGoogle ScholarPubMed
Traber, MG, Winklhofer-Roob, BM, Roob, JM, Khoschsorur, G, Aigner, R & Cross, C (2001) Vitamin E kinetics in smokers and nonsmokers. Free Radic Biol Med 31, 13681374.CrossRefGoogle ScholarPubMed