Skip to main content Accessibility help
×
Home

Association between dietary insulin index and load and psychological disorders

  • Javad Anjom-Shoae (a1) (a2), Ammar Hassanzadeh Keshteli (a3), Hamid Afshar (a4), Ahmad Esmaillzadeh (a2) (a5) (a6) and Peyman Adibi (a7)...

Abstract

The present study was carried out to determine whether the dietary insulin index (DII) and dietary insulin load (DIL) are related to psychological disorders in a cross-sectional study among adults. A total of 3172 Iranian adults (age range of 18–55 years) were included. Data on dietary intakes were collected using a validated dish-based 106-item semi-quantitative FFQ. DII and DIL were calculated using food insulin index values published earlier. To assess depression and anxiety, an Iranian validated version of the Hospital Anxiety and Depression Scale was used. Furthermore, psychological distress was examined using the General Health Questionnaire. Among women, a significant positive association was seen; such that women in the highest quartile of DIL had higher odds of depression than those in the lowest quartile (OR 1·84; 95 % CI 1·14, 2·96). In terms of DII, in the fully adjusted model, women in the top quartile of DII were more likely to be depressed compared with those in the bottom quartile (OR 1·65; 95 % CI 1·05, 2·58). In conclusion, we found a significant positive association between DIL and DII and odds of depression among women, but not in men. However, such findings were not seen for anxiety and psychological distress.

Copyright

Corresponding author

*Corresponding author: Ahmad Esmaillzadeh, fax +98-21-88984861, email a-esmaillzadeh@tums.ac.ir

References

Hide All
1. Bell, SJ & Sears, B (2003) Low-glycemic-load diets: impact on obesity and chronic diseases. Crit Rev Food Sci Nutr 43, 357377.
2. Salmerón, J, Ascherio, A, Rimm, EB, et al. (1997) Dietary fiber, glycemic load, and risk of NIDDM in men. Diabetes Care 20, 545550.
3. Liu, S, Willett, WC, Stampfer, MJ, et al. (2000) A prospective study of dietary glycemic load, carbohydrate intake, and risk of coronary heart disease in US women. Am J Clin Nutr 71, 14551461.
4. Perry, BI, Khandaker, GM, Marwaha, S, et al. (2019) Insulin resistance and obesity, and their association with depression in relatively young people: findings from a large UK birth cohort. Psychol Med (epublication ahead of print version 11 March 2019).
5. Akpalu, J, Yorke, E, Ainuson-Quampah, J, et al. (2018) Depression and glycaemic control among type 2 diabetes patients: a cross-sectional study in a tertiary healthcare facility in Ghana. BMC Psychiatry 18, 357.
6. Lee, JH, Park, SK, Ryoo, JH, et al. (2017) The association between insulin resistance and depression in the Korean general population. J Affect Disord 15, 553559.
7. Anderson, RJ, Freedland, KE, Clouse, RE, et al. (2001) The prevalence of comorbid depression in adults with diabetes: a meta-analysis. Diabetes Care 24, 10691078.
8. Mwamburi, DM, Liebson, E, Folstein, M, et al. (2011) Depression and glycemic intake in the homebound elderly. J Affect Disord 132, 9498.
9. Shomaker, LB, Kelly, NR, Pickworth, CK, et al. (2016) A randomized controlled trial to prevent depression and ameliorate insulin resistance in adolescent girls at risk for type 2 diabetes. Ann Behav Med 50, 762774.
10. Okamura, F, Tashiro, A, Utsumi, A, et al. (1999) Insulin resistance in patients with depression and its changes in the clinical course of depression: a report on three cases using the minimal model analysis. Intern Med 38, 257260.
11. Markus, CR (2007) Effects of carbohydrates on brain tryptophan availability and stress performance. Biol Psychol 76, 8390.
12. Moghaddam, E, Vogt, JA & Wolever, TM (2006) The effects of fat and protein on glycemic responses in nondiabetic humans vary with waist circumference, fasting plasma insulin, and dietary fiber intake. J Nutr 136, 25062511.
13. Nuttall, FQ & Gannon, MC (1991) Plasma glucose and insulin response to macronutrients in nondiabetic and NIDDM subjects. Diabetes Care l4, 824838.
14. Holt, SH, Miller, JC & Petocz, P (1997) An insulin index of foods: the insulin demand generated by 1000-kJ portions of common foods. Am J Clin Nutr 66, 12641276.
15. Bao, J, de Jong, V, Atkinson, F, et al. (2009) Food insulin index: physiologic basis for predicting insulin demand evoked by composite meals. Am J Clin Nutr 90, 986992.
16. Adibi, P, Keshteli, AH, Esmaillzadeh, A, et al. (2012) The Study on the Epidemiology of Psychological, Alimentary Health and Nutrition (SEPAHAN): overview of methodology. J Res Med Sci 17, 292298.
17. Salari-Moghaddam, A, Keshteli, AH, Adibi, P, et al. (2018) Association between dietary inflammatory index and psychological profile in adults. Clin Nutr 38, 23602368.
18. Willett, W (2013) Nutritional Epidemiology. Oxford: Oxford University Press.
19. Keshteli, A, Esmaillzadeh, A, Rajaie, S, et al. (2014) A dish based semi-quantitative food frequency questionnaire for assessment of dietary intakes in epidemiologic studies in Iran: design and development. Int J Prev Med 5, 2936.
20. Ghaffarpour, M, Houshiar-Rad, A & Kianfar, H (1999) The Manual for Household Measures, Cooking Yields Factors and Edible Portion of Foods. Tehran: Nashre Olume Keshavarzy.
21. Kimura, Y, Wada, T, Okumiya, K, et al. (2012) Eating alone among community-dwelling Japanese elderly: association with depression and food diversity. J Nutr Health Aging 16, 728731.
22. Salehi-Abargouei, A, Esmaillzadeh, A, Azadbakht, L, et al. (2016) Nutrient patterns and their relation to general and abdominal obesity in Iranian adults: findings from the SEPAHAN study. Eur J Nutr 55, 505518.
23. Montazeri, A, Vahdaninia, M, Ebrahimi, M, et al. (2003) The Hospital Anxiety and Depression Scale (HADS): translation and validation study of the Iranian version. Health Qual Life Outcomes 28, 114.
24. Montazeri, A, Harirchi, AM, Shariati, M, et al. (2003) The 12-item General Health Questionnaire (GHQ-12): translation and validation study of the Iranian version. Health Qual Life Outcomes 13, 166.
25. Schmitz, N, Kruse, J, Heckrath, C, et al. (1999) Diagnosing mental disorders in primary care: the General Health Questionnaire (GHQ) and the Symptom Check List (SCL-90-R) as screening instruments. Soc Psychiatry Psychiatr Epidemiol 34, 360366.
26. Goldberg, DP, Gater, R, Sartorius, N, et al. (1997) The validity of two versions of the GHQ in the WHO study of mental illness in general health care. Psychol Med 27, 191197.
27. Papassotiropoulos, A, Heun, R & Maier, W (1997) Age and cognitive impairment influence the performance of the General Health Questionnaire. Compr Psychiatry 38, 335340.
28. Aminianfar, A, Saneei, P, Nouri, M, et al. (2019) Validity of self-reported height, weight, body mass index and waist circumference in Iranian adults. Int J Prevent Med (In the Press).
29. Willett, WC, Howe, GR & Kushi, LH (1997) Adjustment for total energy intake in epidemiologic studies. Am J Clin Nutr 65, 12201228.
30. Everson, SA, Maty, SC, Lynch, JW, et al. (2002) Epidemiologic evidence for the relation between socioeconomic status and depression, obesity, and diabetes. J Psychosom Res 53, 891895.
31. Firth, J, Teasdale, SB & Allott, K, et al. (2019) The efficacy and safety of nutrient supplements in the treatment of mental disorders: a meta-review of meta-analyses of randomized controlled trials. World Psychiatry 18, 308324.
32. Murphy, JM, Horton, NJ, Laird, NM, et al. (2004) Anxiety and depression: a 40-year perspective on relationships regarding prevalence, distribution, and comorbidity. Acta Psychiatr Scand 109, 355375.
33. Olesen, J, Gustavsson, A, Svensson, M, et al. (2012) The economic cost of brain disorders in Europe. Eur J Neurol 19, 155162.
34. Le Port, A, Gueguen, A, Kesse-Guyot, E, et al. (2012) Association between dietary patterns and depressive symptoms over time: a 10-year follow-up study of the GAZEL cohort. PLOS ONE 7, 515593.
35. Gangwisch, JE, Hale, L, Garcia, L, et al. (2015) High glycemic index diet as a risk factor for depression: analyses from the Women’s Health Initiative. Am J Clin Nutr 102, 454463.
36. Haghighatdoost, F, Azadbakht, L, Keshteli, AH, et al. (2016) Glycemic index, glycemic load, and common psychological disorders. Am J Clin Nutr 103, 201209.
37. Aparicio, A, Robles, F, Lopez-Sobaler, AM, et al. (2013) Dietary glycaemic load and odds of depression in a group of institutionalized elderly people without antidepressant treatment. Eur J Nutr 52, 10591066.
38. Murakami, K, Miyake, Y, Sasaki, S, et al. (2008) Dietary glycemic index and load and the risk of postpartum depression in Japan: the Osaka Maternal and Child Health Study. J Affect Disord 110, 174179.
39. Gopinath, B, Flood, VM, Burlutksy, G, et al. (2017) Association between carbohydrate nutrition and prevalence of depressive symptoms in older adults. Br J Nutr 116, 21092114.
40. Salari-Moghaddam, A, Saneei, P, Larijani, B, et al. (2019) Glycemic index, glycemic load, and depression: a systematic review and meta-analysis. Eur J Clin Nutr 73, 356365.
41. Bell, KJ, Petocz, P, Colagiuri, S, et al. (2016) Algorithms to improve the prediction of postprandial insulinaemia in response to common foods. Nutrients 8, 210.
42. Holst, JJ & Gromada, J (2004) Role of incretin hormones in the regulation of insulin secretion in diabetic and nondiabetic humans. Am J Physiol Endocrinol Metab 287, 199206.
43. Collier, G, McLean, A & O’Dea, K (1984) Effect of co-ingestion of fat on the metabolic responses to slowly and rapidly absorbed carbohydrates. Diabetologia 26, 5054.
44. Laurin, C, Lavoie, KL, Bacon, SL, et al. (2007) Sex differences in the prevalence of psychiatric disorders and psychological distress in patients with COPD. Chest 132, 148155.
45. Nolen-Hoeksema, S (2012) Gender differences in depression. Annu Rev Clin Psychol 8, 161187.
46. Beer-Borst, S, Hercberg, S, Morabia, A, et al. (2000) Dietary patterns in six European populations: results from EURALIM, a collaborative European data harmonization, and information campaign. Eur J Clin Nutr 54, 253262.
47. O’Doherty Jensen, K & Holm, L (1999) Preferences, quantities, and concerns: socio-cultural perspectives on the gendered consumption of foods. Eur J Clin Nutr 53, 351359.
48. Marks, GC, Hughes, MC & van der Pols, JC (2006) Relative validity of food intake estimates using a food frequency questionnaire is associated with sex, age, and other personal characteristics. J Nutr 136, 459465.
49. Szczesny, E, Slusarczyk, J, Glombik, K, et al. (2013) Possible contribution of IGF-1 to depressive disorder. Pharmacol Rep 65, 16221631.
50. Grillo, CA, Mulder, P, Macht, VA, et al. (2014) Dietary restriction reverses obesity-induced anhedonia. Physiol Behav 128, 126132.
51. McIntyre, RS, Kenna, HA, Nguyen, HT, et al. (2010) Brain volume abnormalities and neurocognitive deficits in diabetes mellitus: points of pathophysiological commonality with mood disorders? Adv Ther 27, 6380.
52. Rumsfeld, JS & Ho, PM (2005) Depression and cardiovascular disease: a call for recognition. Circulation 111, 250253.
53. Beagley, J, Guariguata, L, Weil, C, et al. (2014) Global estimates of undiagnosed diabetes in adults. Diabetes Res Clin Pract 103, 150160.
54. Chauvet-Gelinier, JC, Roussot, A, Cottenet, J, et al. (2019) Depression and obesity, data from a national administrative database study: geographic evidence for an epidemiological overlap. PLOS ONE 14, e0210507.
55. Anjom-Shoae, J, Keshteli, AH, Sadeghi, O, et al. (2019) Association between dietary insulin index and load with obesity in adults. Eur J Nutr (Epublication ahead of print version 30 May 2019).

Keywords

Related content

Powered by UNSILO

Association between dietary insulin index and load and psychological disorders

  • Javad Anjom-Shoae (a1) (a2), Ammar Hassanzadeh Keshteli (a3), Hamid Afshar (a4), Ahmad Esmaillzadeh (a2) (a5) (a6) and Peyman Adibi (a7)...

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed.