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Assessment of thiamin (vitamin B1) and riboflavin (vitamin B2) status in an adult Mediterranean population

  • J. Mataix (a1), P. Aranda (a1), C. Sánchez (a1), M. A. Montellano (a1), E. Planells (a1) and J. Llopis (a1)...

Abstract

The aim of the present study was to assess the nutritional status for thiamin (vitamin B1) and riboflavin (vitamin B2) in an adult Mediterranean population, in order to identify patterns of intake, groups at risk for deficiency and factors that might influence this risk. A cross-sectional survey was carried out in Andalusia, a western Mediterranean region in southern Spain. Nutrient intakes were studied in a random sample of 3390 subjects (1746 men, 1644 women) who were between 25 and 60 years of age. Blood samples were obtained for biochemical assays in a random subsample of 372 subjects (181 men, 191 women). Food consumption was assessed by 48 h recall. Vitamin B1 and B2 were measured as erythrocyte transketolase and as erythrocyte glutathione reductase activation coefficients, respectively. Energy and vitamin intakes were significantly higher in men than in women. Intakes were below two-thirds of the recommended dietary allowance for vitamin B1 in 7·80% of the men and 4·50% of the woman, and were below this level for vitamin B2 in 18·00% of the men and 11·70 % of the women. Age, educational level, alcohol use and smoking were also associated with differences in the intake of these nutrients. Biochemical analyses showed that vitamin B1 and B2 status was deficient in 6·40 and 5·30% of the population, respectively. Although factors such as gender, age, level of education, drinking and smoking can have an effect on the risk of inadequate intake of these nutrients, these factors did not affect biochemical indices of nutritional status in the present study.

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Corresponding author

*Corresponding author: Dr Juan Llopis, fax +34 958 248959, email jllopis@ugr.es

References

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Alberti-Fidanza, A, Burini, G, Genipi, L, Maurizi-Coli, A & Fidanza, F (1998) Vitamin intake and status in a group of subjects from the Gubbio area in Italy. Int J Vitam Nutr Res 68, 249254.
Ambrose, ML, Bowden, SC & Whelan, G (2001) Thiamin treatment and working memory function of alcohol-dependent people: preliminary findings. Alcohol Clin Exp Res 25, 112116.
Bailey, AL, Finglas, PM, Wright, AJ & Southon, S (1994) Thiamine intake, erythrocyte transketolase (EC 2.2.1.1.) activity and total erythrocyte thiamin in adolescents. Br J Nutr 72, 111125.
Bailey, AL, Maisey, S, Southon, S, Wright, AJ, Finglas, PM & Fulcher, RA (1997) Relationships between micronutrient intake and biochemical indicators of nutrient adequacy in a ‘free-living’ elderly UK population. Br J Nutr 77, 225242.
Benton, D, Haller, J & Fordy, J (1997) The vitamin status of young British adults. Int J Vitam Nutr Res 67, 3440.
Boisvert, WA, Castañeda, C, Mendoza, I, et al. (1993) Prevalence of riboflavin deficiency among Guatemalan elderly people and its relationship to milk intake. Am J Clin Nutr 58, 8590.
Booth, CK, Clark, T & Fenn, A (1998) Folic acid, riboflavin, thiamine, and vitamin B-6 status of a group of first-time blood donors. Am J Clin Nutr 68, 10751080.
Bovet, P, Larue, D, Fayol, V & Paccaud, F (1998) Blood thiamin status and determinants in the population of Seychelles (Indian Ocean). J Epidemiol Community Health 52, 237242.
Cameron, ME & Van Staveren, WA (1988) Manual on Methodology for Food Consumption Studies, pp. 8384. Oxford: Oxford University Press.
Carbajal, A, Nuñez, C & Moreiras, O (1996) Energy intake as a determinant factor of vitamin status in healthy young women. Int J Vitam Nutr Res 66, 227231.
de Carvalho, MJ, Guilland, JC, Moreau, D, Boggio, V & Fuchs, F (1996) Vitamin status of healthy subjects in Burgundy (France). Ann Nutr Metab 40, 2451.
El-Hazmi, MA & Warsy, AS (1987) Riboflavin status in a Saudi population – a study in Riyadh. Ann Nutr Metab 31, 253258.
Fidanza, F, Brubacher, G, Simonetti, MS & Mariani, L (1984) Nutritional status of the elderly. III. Vitamin nutriture of elderly pensioners in Perugia. Int J Vitam Nutr Res 54, 355359.
Fogelholm, GM, Himberg, JJ, Alopaeus, K, et al. (1992) Dietary and biochemical indices of nutritional status in male athletes and controls. J Am Coll Nutr 11, 181189.
González-Gross, M, Ortega, RM, Andres, P & Varela, G (1991) Riboflavin status in a group of institutionalized elderly. Int J Vitam Nutr Res 61, 120124.
Guillén, M, Corella, D, Portoles, O, González, JI, Mulet, F & Saiz, C (2001) Prevalence of the methylenetetrahydrofolate reductase 677C>T in the Mediterranean Spanish population. Association with cardiovascular risk factors. Eur J Epidemiol 17, 255261.
Hercberg, S, Preziosi, P, Galan, P, et al. (1994) Vitamin status of a healthy French population: dietary intakes and biochemical markers. Int J Vitam Nutr Res 64, 220232.
Herve, C, Beyne, P, Letteron, P & Delacoux, E (1995) Comparison of erythrocyte transketolase activity with thiamine and thiamine phosphatase ester in chronic alcoholic patients. Clin Chim Acta 31, 91100.
Hiraoka, M (2001) Nutritional status of vitamin A, E, C, B1, B2, B6, nicotinic acid, B12, folate, and beta-carotene in young women. J Nutr Sci Vitaminol (Tokyo) 47, 2027.
Institute of Medicine (1998) Dietary Reference Intakes for Thiamine, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin and Choline, pp. 58122. Washington, DC: National Academic Press.
Instituto de Estadística de Andalucía (2001) Andalucía. Datos Básicos. Sevilla, Spain: Consejería de Economía y Hacienda, Junta de Andalucía. http://www.iea.junta-andalucia.es
López-Sobaler, AM, Ortega, RM, Quintas, ME, et al. (2002) The influence of vitamin B2 intake on the activation coefficient of erythrocyte glutathione reductase in the elderly. J Nutr Health Aging 6, 6062.
McNulty, H, McKinley, MC, Wilson, B, et al. (2002) Impaired functioning of thermolabile methylenetetrahydrofolate reductase is dependent on riboflavin status: implications for riboflavin requirements. Am J Clin Nutr 76, 436441.
Manore, MM (2000) Effect of physical activity on thiamine, riboflavine, and vitamin B6 requirements. Am J Clin Nutr 72, 598S606S.
Mataix, J, Mañas, M, Llopis, J, Martínez, de, Victoria, E, Sánchez, J & Borregón, A (1998) Tablas de Composición de Alimentos Españoles (Spanish Food Consumption Tables). Granada, Spain: Editorial Universidad de Granada.
Ministerio de, Agricultura Pesca y Alimentación (2000) La Alimentación en España. Madrid, Spain: Ministerio de Agricultura Pesca y Alimentación, Dirección General de Alimentación.
Ministerio de, Sanidad y Consumo (1997) Encuesta Nacional de Salud. Madrid, Spain: Ministerio de Sanidad y Consumo.
Moreiras, O, Carbajal, A & Campo, M (1995) Tendencias de los hábitos alimentarios y estado nutritional en España. Resultados de las Encuestas de presupuestos familiars (Tendencies of the nourishing habits and nutritional state in Spain. Results of the surveys of family budgets). In Guias Alimentarias para la Población Española, pp. 104117 [Serra,, L, Aranceta, JMataix, J, editors]. Barcelona, Spain: SG Editores.
Ortega, RM, Mena, MC, Faci, M, Santana, JF & Serra-Manjem, L (2001) Vitamin status in different groups of the Spanish population: a meta-analysis of national studies performed between 1990 and 1999. Public Health Nutr 4, 13251329.
Pinto, JT, Huang, YP & Rivlin, RS (1987) Mechanisms underlying the differential effects of ethanol upon the bioavailability of riboflavin and flavin adenine dinucleotide. J Clin Invest 79, 13431348.
Prentice, AM & Bates, CJ (1981) A biochemical evaluation of the erythrocyte glutathione reductase (EC 1.6.4.2) test for riboflavin status. 2. Dose–response relationships in chronic marginal deficiency. Br J Nutr 45, 5365.
Quandt, SA (1998) Social and cultural influences on food consumption and nutritional status. In Modern Nutrition in Health and Disease, pp. 17831792 [Shils,, ME, Olson,, JA, Shike, MRoss, AC, editors]. Philadelphia, PA: Lippincott Williams & Wilkins.
Sánchez, DJ, Murphy, MM, Bosh-Sabater, J & Fernandez-Ballart, J (1999) Enzymic evaluation of thiamin, riboflavin and pyridoxine status of parturient mothers and their newborn infants in a Mediterranean area of Spain. Eur J Clin Nutr 53, 2738.
Sauberlich, HE (1999) Laboratory Tests for the Assessment of Nutritional Status, pp. 3769. Boca Raton, FL: CRC Press.
Serra-Manjem, L, Ribas, L, Gárcía, R, et al. (1996) The Evaluation of Nutritional Status in Catalonia, Spain (1992–93). Barcelona, Spain: Departament de Sanitat i Seguretat Social, Generalitat de Catalunya.
Varela, G (1994) Tablas de Ingestas Recomendadas en Energía y Nutrientes para la Población Española (Recommended Dietary Allowance for the Spanish Population). Madrid, Spain: Departamento de Bromatología, Universidad Complutense.
Varela, G, Moreiras, O & Blázquez, MJ (1985) Urbanization, nutritive status and food habits in the Spanish population. Bibl Nutr Dieta 36, 5571.
Varela, G, Moreiras, O, Carvajal, A & Campo, M (1995) Encuesta de Presupuestos Familiares 1990–1991 (Family Budgets Survey). Madrid, Spain: Instituto Nacional de Estadística.
Vuilleuimier, JP, Keller, HE, Rettenmaier, R & Hunzinker, F (1983) Clinical chemical methods for the routine assessment of the vitamin status in human populations. Part II: The water-soluble vitamins B1, B2, and B6. Int J Vitam Nutr Res 53, 359370.
Willett, WC & Stampfer, MJ (1986) Total energy intake: Implications for epidemiologic analyses. Am J Epidemiol 124, 1727.

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