Skip to main content Accessibility help
×
Home

Alternative Healthy Eating Index 2010, Dietary Inflammatory Index and risk of mortality: results from the Whitehall II cohort study and meta-analysis of previous Dietary Inflammatory Index and mortality studies

  • Nitin Shivappa (a1) (a2) (a3), James R. Hebert (a1) (a2) (a3), Mika Kivimaki (a4) and Tasnime Akbaraly (a4) (a5)
  • Please note a correction has been issued for this article.

Abstract

We aimed to examine the association between the Alternative Healthy Eating Index updated in 2010 (AHEI-2010), the Dietary Inflammatory Index (DIITM) and risk of mortality in the Whitehall II study. We also conducted a meta-analysis on the DII-based results from previous studies to summarise the overall evidence. Data on dietary behaviour assessed by self-administered repeated FFQ and on mortality status were available for 7627 participants from the Whitehall II cohort. Cox proportional hazards regression models were performed to assess the association between cumulative average of AHEI-2010 and DII scores and mortality risk. During 22 years of follow-up, 1001 participants died (450 from cancer, 264 from CVD). Both AHEI-2010 (mean=48·7 (sd 10·0)) and DII (mean=0·37 (sd 1·41)) were associated with all-cause mortality. The fully adjusted hazard ratio (HR) per sd, were 0·82; 95 % CI 0·76, 0·88 for AHEI-2010 and 1·18; 95 % CI 1·08, 1·29 for DII. Significant associations were also observed with cardiovascular and cancer mortality risk. For DII, a meta-analysis (using fixed effects) from this and four previous studies showed a positive association of DII score with all-cause (HR=1·04; 95 % CI 1·03, 1·05, 28 891deaths), cardiovascular (HR=1·05; 95 % CI 1·03, 1·07, 10 424 deaths) and cancer mortality (HR=1·05; 95 % CI 1·03, 1·07, n 8269).The present study confirms the validity to assess overall diet through AHEI-2010 and DII in the Whitehall II cohort and highlights the importance of considering diet indices related to inflammation when evaluating all-cause, cardiovascular and cancer mortality risk.

Copyright

Corresponding author

* Corresponding author: Dr N. Shivappa, fax +1 803 576 5624, email shivappa@mailbox.sc.edu

Footnotes

Hide All

The original version of this article was published with the incorrect title. A notice detailing this has been published and the error rectified in the online and print PDF and HTML copies.

Footnotes

References

Hide All
1. Schwingshackl, L & Hoffmann, G (2015) Diet quality as assessed by the Healthy Eating Index, the Alternate Healthy Eating Index, the Dietary Approaches to Stop Hypertension score, and health outcomes: a systematic review and meta-analysis of cohort studies. J Acad Nutr Diet 115, 780800.e785 (Epublication ahead of print version 11 February 2015).
2. Ocke, MC (2013) Evaluation of methodologies for assessing the overall diet: dietary quality scores and dietary pattern analysis. Proc Nutr Soc 72, 191199 (Epublication ahead of print version 30 January 2013).
3. Jacobs, DR Jr. & Steffen, LM (2003) Nutrients, foods, and dietary patterns as exposures in research: a framework for food synergy. Am J Clin Nutr 78, 508S513S.
4. Ouchi, N, Parker, JL, Lugus, JJ, et al. (2011) Adipokines in inflammation and metabolic disease. Nat Rev Immunol 11, 8597.
5. Calabro, P, Golia, E & Yeh, ET (2009) CRP and the risk of atherosclerotic events. Semin Immunopathol 31, 7994.
6. Miller, MA & Cappuccio, FP (2007) Inflammation, sleep, obesity and cardiovascular disease. Curr Vasc Pharmacol 5, 93102.
7. Chung, Y-C & Chang, Y-F (2003) Serum interleukin-6 levels reflect the disease status of colorectal cancer. J Surg Oncol 83, 222226.
8. Terzic, J, Grivennikov, S, Karin, E, et al. (2010) Inflammation and colon cancer. Gastroenterology 138, 21012114. e2105.
9. Toriola, AT, Cheng, TY, Neuhouser, ML, et al. (2013) Biomarkers of inflammation are associated with colorectal cancer risk in women but are not suitable as early detection markers. Int J Cancer 132, 26482658.
10. Lin, OS (2009) Acquired risk factors for colorectal cancer. Methods Mol Biol 472, 361372.
11. Wogan, GN, Hecht, SS, Felton, JS, et al. (2004) Environmental and chemical carcinogenesis. Semin Cancer Biol 14, 473486.
12. de Mello, VD, Schwab, U, Kolehmainen, M, et al. (2011) A diet high in fatty fish, bilberries and wholegrain products improves markers of endothelial function and inflammation in individuals with impaired glucose metabolism in a randomised controlled trial: the Sysdimet study. Diabetologia 54, 27552767.
13. Khoo, J, Piantadosi, C, Duncan, R, et al. (2011) Comparing effects of a low-energy diet and a high-protein low-fat diet on sexual and endothelial function, urinary tract symptoms, and inflammation in obese diabetic men. J Sex Med 8, 28682875.
14. Luciano, M, Mottus, R, Starr, JM, et al. (2012) Depressive symptoms and diet: their effects on prospective inflammation levels in the elderly. Brain Behav Immun 26, 717720.
15. Chang, AR, Lazo, M, Appel, LJ, et al. (2014) High dietary phosphorus intake is associated with all-cause mortality: results from NHANES III. Am J Clin Nutr 99, 320327.
16. Cheung, CL, Sahni, S, Cheung, BM, et al. (2015) Vitamin K intake and mortality in people with chronic kidney disease from NHANES III. Clin Nutr 34, 235240.
17. Cohen, HW, Hailpern, SM & Alderman, MH (2008) Sodium intake and mortality follow-up in the Third National Health and Nutrition Examination Survey (NHANES III). J Gen Intern Med 23, 12971302.
18. Deng, X, Song, Y, Manson, JE, et al. (2013) Magnesium, vitamin D status and mortality: results from US National Health and Nutrition Examination Survey (NHANES) 2001 to 2006 and NHANES III. BMC Med 11, 187.
19. Shivappa, N, Steck, SE, Hurley, TG, et al. (2014) Designing and developing a literature-derived, population-based dietary inflammatory index. Public Health Nutr 17, 16891696.
20. Shivappa, N, Steck, SE, Hurley, TG, et al. (2014) A population-based dietary inflammatory index predicts levels of C-reactive protein in the Seasonal Variation of Blood Cholesterol Study (SEASONS). Public Health Nutr 17, 18251833.
21. Wirth, MD, Burch, J, Shivappa, N, et al. (2014) Association of a dietary inflammatory index with inflammatory indices and metabolic syndrome among police officers. J Occup Environ Med 56, 986989.
22. Shivappa, N, Hebert, JR, Rietzschel, ER, et al. (2015) Associations between dietary inflammatory index and inflammatory markers in the Asklepios Study. Br J Nutr 113, 665671.
23. Tabung, FK, Steck, SE, Zhang, J, et al. (2015) Construct validation of the dietary inflammatory index among postmenopausal women. Ann Epidemiol 25, 398405.
24. Wood, LG, Shivappa, N, Berthon, BS, et al. (2015) Dietary inflammatory index is related to asthma risk, lung function and systemic inflammation in asthma. Clin Exp Allergy 45, 177183.
25. Chiuve, SE, Fung, TT, Rimm, EB, et al. (2012) Alternative dietary indices both strongly predict risk of chronic disease. J Nutr 142, 10091018.
26. Marmot, M & Brunner, E (2005) Cohort profile: the Whitehall II study. Int J Epidemiol 34, 251256.
27. Akbaraly, TN, Ferrie, JE, Berr, C, et al. (2011) Alternative Healthy Eating Index and mortality over 18 y of follow-up: results from the Whitehall II cohort. Am J Clin Nutr 94, 247253.
28. Brunner, E, Stallone, D, Juneja, M, et al. (2001) Dietary assessment in Whitehall II: comparison of 7 d diet diary and food-frequency questionnaire and validity against biomarkers. Br J Nutr 86, 405414.
29. Bingham, SA, Gill, C, Welch, A, et al. (1997) Validation of dietary assessment methods in the UK arm of EPIC using weighed records, and 24-hour urinary nitrogen and potassium and serum vitamin C and carotenoids as biomarkers. Int J Epidemiol 26, Suppl. 1, S137S151.
30. Shivappa, N, Bosetti, C, Zucchetto, A, et al. (2015) Association between dietary inflammatory index and prostate cancer among Italian men. Br J Nutr 113, 278283.
31. Shivappa, N, Prizment, AE, Blair, CK, et al. (2014) Dietary inflammatory index and risk of colorectal cancer in the Iowa Women’s Health Study. Cancer Epidemiol Biomarkers Prev 23, 23832392.
32. Sabia, S, Dugravot, A, Kivimaki, M, et al. (2012) Effect of intensity and type of physical activity on mortality: results from the Whitehall II cohort study. Am J Public Health 102, 698704.
33. Graffouillere, L, Deschasaux, M, Mariotti, F, et al. (2016) Prospective association between the Dietary Inflammatory Index and mortality: modulation by antioxidant supplementation in the SU.VI.MAX randomized controlled trial. Am J Clin Nutr 103, 878885.
34. Shivappa, N, Steck, SE, Hussey, JR, et al. (2016) Inflammatory potential of diet and all-cause, cardiovascular, and cancer mortality in National Health and Nutrition Examination Survey III Study. Eur J Nutr 56, 683692.
35. Shivappa, N, Blair, CK, Prizment, AE, et al. (2016) Association between inflammatory potential of diet and mortality in the Iowa Women’s Health study. Eur J Nutr 55, 14911502.
36. Shivappa, N, Harris, H, Wolk, A, et al. (2016) Association between inflammatory potential of diet and mortality among women in the Swedish Mammography Cohort. Eur J Nutr 55, 18911900.
37. Guolo, A & Varin, C (2015) Random-effects meta-analysis: the number of studies matters. Stat Methods Med Res.
38. Onvani, S, Haghighatdoost, F, Surkan, PJ, et al. (2016) Adherence to the Healthy Eating Index and Alternative Healthy Eating Index dietary patterns and mortality from all causes, cardiovascular disease and cancer: a meta-analysis of observational studies. J Hum Nutr Diet.
39. Erlinger, TP, Platz, EA, Rifai, N, et al. (2004) C-reactive protein and the risk of incident colorectal cancer. JAMA 291, 585590.
40. Gunter, MJ, Stolzenberg-Solomon, R, Cross, AJ, et al. (2006) A prospective study of serum C-reactive protein and colorectal cancer risk in men. Cancer Res 66, 24832487.
41. Otani, T, Iwasaki, M, Sasazuki, S, et al. (2006) Plasma C-reactive protein and risk of colorectal cancer in a nested case-control study: Japan Public Health Center-based prospective study. Cancer Epidemiol Biomarkers Prev 15, 690695.
42. Nikiteas, NI, Tzanakis, N, Gazouli, M, et al. (2005) Serum IL-6, TNFalpha and CRP levels in Greek colorectal cancer patients: prognostic implications. World J Gastroenterol 11, 16391643.
43. Herszenyi, L & Tulassay, Z (2010) Epidemiology of gastrointestinal and liver tumors. Eur Rev Med Pharmacol Sci 14, 249258.
44. Shivappa, N, Bosetti, C, Zucchetto, A, et al. (2015) Dietary inflammatory index and risk of pancreatic cancer in an Italian case-control study. Br J Nutr 113, 292298.
45. Lu, Y, Shivappa, N, Lin, Y, et al. (2016) Diet-related inflammation and oesophageal cancer by histological type: a nationwide case-control study in Sweden. Eur J Nutr 55, 16831694.
46. Shivappa, N, Hebert, JR & Rashidkhani, B (2015) Dietary inflammatory index and risk of esophageal squamous cell cancer in a case-control study from Iran. Nutr Cancer 67, 12531259.
47. Shivappa, N, Zucchetto, A, Serraino, D, et al. (2015) Dietary inflammatory index and risk of esophageal squamous cell cancer in a case-control study from Italy. Cancer Causes Control 26, 14391447.
48. Tabung, FK, Steck, SE, Ma, Y, et al. (2015) The association between dietary inflammatory index and risk of colorectal cancer among postmenopausal women: results from the Women’s Health Initiative. Cancer Causes Control 26, 399408.
49. O’Neil, A, Shivappa, N, Jacka, FN, et al. (2015) Pro-inflammatory dietary intake as a risk factor for CVD in men: a 5-year longitudinal study. Br J Nutr 114, 20742082.
50. Ramallal, R, Toledo, E, Martinez-Gonzalez, MA, et al. (2015) Dietary inflammatory index and incidence of cardiovascular disease in the SUN cohort. PLOS ONE 10, e0135221.
51. Garcia-Arellano, A, Ramallal, R, Ruiz-Canela, M, et al. (2015) Dietary Inflammatory Index and Incidence of Cardiovascular Disease in the PREDIMED Study. Nutrients 7, 41244138.
52. Zucchetto, A, Gini, A, Shivappa, N, et al. (2016) Dietary inflammatory index and prostate cancer survival. Int J Cancer 139, 23982404.
53. Esmaillzadeh, A, Kimiagar, M, Mehrabi, Y, et al. (2007) Dietary patterns and markers of systemic inflammation among Iranian women. J Nutr 137, 992998.
54. Festa, A, D’Agostino, R, Howard, G, et al. (2000) Chronic subclinical inflammation as part of the insulin resistance syndrome: the Insulin Resistance Atherosclerosis Study (IRAS). Circulation 102, 4247.
55. Bruce, WR, Wolever, TM & Giacca, A (2000) Mechanisms linking diet and colorectal cancer: the possible role of insulin resistance. Nutr Cancer 37, 1926.
56. Bruce, WR, Giacca, A & Medline, A (2000) Possible mechanisms relating diet and risk of colon cancer. Cancer Epidemiol Biomarkers Prev 9, 12711279.
57. Neelakantan, N, Naidoo, N, Koh, WP, et al. (2016) The alternative healthy eating index is associated with a lower risk of fatal and nonfatal acute myocardial infarction in a Chinese adult population. J Nutr 146, 13791386.
58. Murakami, K & Livingstone, MBE (2016) Energy density of meals and snacks in the British diet in relation to overall diet quality, BMI and waist circumference: findings from the National Diet and Nutrition Survey. Br J Nutr 116, 14791489.
59. Lundberg-Hallén, N & Öhrvik, V (2015) Key foods in Sweden: identifying high priority foods for future food composition analysis. J Food Compos Anal 37, 5157.
60. Jain, M, Howe, GR, Harrison, L, et al. (1989) A study of repeatability of dietary data over a seven-year period. Am J Epidemiol 129, 422429.
61. Jensen, OM, Wahrendorf, J, Rosenqvist, A, et al. (1984) The reliability of questionnaire-derived historical dietary information and temporal stability of food habits in individuals. Am J Epidemiol 120, 281290.
62. Lindsted, KD & Kuzma, JW (1989) Long-term (24-year) recall reliability in cancer cases and controls using a 21-item food frequency questionnaire. Nutr Cancer 12, 135149.
63. Mursu, J, Steffen, LM, Meyer, KA, et al. (2013) Diet quality indexes and mortality in postmenopausal women: the Iowa Women’s Health Study. Am J Clin Nutr 98, 444453.
64. Sijtsma, FP, Meyer, KA, Steffen, LM, et al. (2012) Longitudinal trends in diet and effects of sex, race, and education on dietary quality score change: the Coronary Artery Risk Development in Young Adults study. Am J Clin Nutr 95, 580586.
65. Thompson, FE, Metzner, HL, Lamphiear, DE, et al. (1990) Characteristics of individuals and long term reproducibility of dietary reports: the Tecumseh Diet Methodology Study. J Clin Epidemiol 43, 11691178.

Keywords

Type Description Title
WORD
Supplementary materials

Shivappa et al supplementary material
Table A

 Word (38 KB)
38 KB
UNKNOWN
Supplementary materials

Shivappa et al supplementary material
Figure B

 Unknown (68 KB)
68 KB
WORD
Supplementary materials

Shivappa et al supplementary material
Figure A

 Word (43 KB)
43 KB

Metrics

Altmetric attention score

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed

A correction has been issued for this article: