Hostname: page-component-848d4c4894-p2v8j Total loading time: 0 Render date: 2024-05-08T13:49:08.024Z Has data issue: false hasContentIssue false
  • English
  • Français

Absorption of L-histidine and glucose from the jejunum segment of the pig and its diurnal fluctuation

Published online by Cambridge University Press:  09 March 2007

S. Furuya  and
S. Takahashi
S. Furuya
Affiliation:
Department of Nutrition, National Institute of Animal Industry, Chiba-Shi 280, Japan
S. Takahashi
Affiliation:
Department of Nutrition, National Institute of Animal Industry, Chiba-Shi 280, Japan
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

1. Flow rate of digesta and its components in the upper jejunum, and the absorption of L-histidine and glucose from the jejunum segment were measured in pigs fitted with three simple cannulas. The pigs were fed once daily at 08.30 hours.

2. A maximum flow of digesta was obtained in the period 10.00–10.30 hours; the flow rate decreased with time after feeding, reaching a minimum in the period 22.00–22.30 hours.

3. The absorption rate for L-histidine and glucose increased in a hyperbolic manner with increasing concentrations of infused test material, which ranged from 2.5 to 20 g/l for each material.

4. L-histidine and glucose were absorbed nearly independently when perfused in combination. The absorption rates for glucose were significantly (P < 0.01) greater than the corresponding rates for L-histidine at each concentration of infusate.

5. The absorption of both L-histidine and glucose expressed as a percentage of the amounts in the perfusate decreased with increasing flow rate of perfusate, from 400 to 800 ml/h. The increase in flow rate from 400 to 800 ml/h was associated with a 20% increase in L-histidine absorption rate; there was a 30% increase in glucose absorption rate when the flow rate was increased to 600 ml/h, but no further increase at 800 ml/h.

6. The absorption of both L-histidine and glucose decreased with time after feeding; the absorption rates for L-histidine and glucose measured for the period 10.00–10.30 hours were 126 and 133%, respectively, of those measured for the period 22.00–22.30 hours.

Type
Papers of direct relevance to Clinical and Human Nutrition
Information
British Journal of Nutrition , Volume 34 , Issue 2 , September 1975 , pp. 267 - 277
Copyright
Copyright © The Nutrition Society 1975

References

Annegers, J. H. (1964). Am. J. Physiol. 206, 1095.CrossRefGoogle Scholar
Association of Official Analytical Chemists (1970). Official Methods of Analysis, 11th ed. Washington, DC: Association of Official Analytical Chemists.Google Scholar
Baril, E. F. & Potter, V. R. (1968). J. Nufr. 95, 228.Google Scholar
Bingham, J. K., Newey, H. & Smyth, D. H. (1966). Biochim. biophys. Acta 130, 281.CrossRefGoogle Scholar
Blankenhorn, D. H., Hirsch, J. & Ahrens, E. H. Jr (1955). Proc. Soc. exp. Biol. Med. 88, 356.CrossRefGoogle Scholar
Cook, G. C. (1971). J. Physiol., Lond. 217, 61.CrossRefGoogle Scholar
Coombe, N. B. & Smith, R. H. (1973). Br. J. Nutr. 30, 331.CrossRefGoogle Scholar
Cummins, A. J. & Jussila, R. (1955). Gastroenterology 29, 982.CrossRefGoogle Scholar
Freeman, C. P., Noakes, D. E., Annison, E. F. & Hill, K. J. (1968). Br. J. Nutr. 22, 739.CrossRefGoogle Scholar
Furuya, S., Takahashi, S. & Omori, S. (1974). Jap. J. zootech. Sci. 45, 42.Google Scholar
Furuya, S. & Yugari, Y. (1971). Biochim. biophys. Acta 241, 245.CrossRefGoogle Scholar
Furuya, S.& Yugari, Y. (1974). Biochim. biophys. Acta 343, 558.CrossRefGoogle Scholar
Hardcastle, P. T., Newey, H. & Smyth, D. H. (1968). J. Physiol., Lond. 196, 33P.Google Scholar
Hellier, M. D., Perrett, D. & Holdsworth, C. D. (1970). Br. med. J. iv, 782.CrossRefGoogle Scholar
Hoffman, W. S. (1937). J. biol. Chem. 120, 51.CrossRefGoogle Scholar
Holdsworth, C. D. & Dawson, A. M. (1964). Clin. Sci. 27, 371.Google Scholar
Lifshitz, F., Hawkins, R. L., Diaz-Bensussen, S. & Wapnir, R. A. (1972). J. Nutr. 102, 1303.CrossRefGoogle Scholar
Macpherson, H. T. (1946). Biochem. J. 40, 470.CrossRefGoogle Scholar
Markowitz, J. (1954). Experimental Surgery, 3rd ed.Baltimore: Williams & Wilkins.Google Scholar
Newey, H. & Smyth, D. H. (1964). Nature, Lond. 202, 400.CrossRefGoogle Scholar
Saito, M. (1972). Biochim. biophys. Acta 286, 212.CrossRefGoogle Scholar
Sanford, P. A., Smyth, D. H. & Watling, M. (1965). J. Physiol., Lond. 179, 72P.Google Scholar
Semenza, G. (1971). Transport Across the Intestine. Edinburgh and London: Churchill Livingstone.Google Scholar
Siddons, R. C., Smith, R. H., Henschel, M. J., Hill, W. B. & Porter, J. W. G. (1969). Br. J. Nutr. 23, 333.CrossRefGoogle Scholar
Smith, R. H. (1958). Nature, Lond. 182, 260.CrossRefGoogle Scholar
Snedecor, G. W. (1956). Statistical Methods, 5th ed. Ames, Iowa: Iowa State University Press.Google Scholar
Technicon Instruments Corporation (1967). Technicon AutoAnalyzer Methodology Sheet N-2b. Tarry Town, New York: Technicon Instruments Corporation.Google Scholar