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Lipomatous muscular ‘dystrophy’ of Piedmontese cattle

Published online by Cambridge University Press:  27 April 2012

E. Biasibetti ,
S. Amedeo ,
A. Brugiapaglia ,
G. Destefanis ,
L. Di Stasio ,
F. Valenza  and
M. T. Capucchio
E. Biasibetti*
Affiliation:
Department of Animal Pathology, Faculty of Veterinary Medicine, University of Torino, via Leonardo da Vinci 44, 10095 Grugliasco (Torino), Italy
S. Amedeo
Affiliation:
Department of Animal Pathology, Faculty of Veterinary Medicine, University of Torino, via Leonardo da Vinci 44, 10095 Grugliasco (Torino), Italy
A. Brugiapaglia
Affiliation:
Department of Animal Science, Faculty of Agriculture, University of Torino, via Leonardo da Vinci 44, 10095 Grugliasco (Torino), Italy
G. Destefanis
Affiliation:
Department of Animal Science, Faculty of Agriculture, University of Torino, via Leonardo da Vinci 44, 10095 Grugliasco (Torino), Italy
L. Di Stasio
Affiliation:
Department of Animal Science, Faculty of Agriculture, University of Torino, via Leonardo da Vinci 44, 10095 Grugliasco (Torino), Italy
F. Valenza
Affiliation:
Department of Animal Pathology, Faculty of Veterinary Medicine, University of Torino, via Leonardo da Vinci 44, 10095 Grugliasco (Torino), Italy
M. T. Capucchio
Affiliation:
Department of Animal Pathology, Faculty of Veterinary Medicine, University of Torino, via Leonardo da Vinci 44, 10095 Grugliasco (Torino), Italy
*
†E-mail: elena.biasibetti@unito.it
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Abstract

Lipomatous myopathy is a degenerative muscle pathology characterized by the substitution of muscle cells with adipose tissue, sporadically reported in cattle, pigs, and rarely in sheep, horses and dogs. This study investigated the pathology of this myopathy in 40 muscle samples collected from regularly slaughtered Piedmontese cattle living in Piedmont region (Italy). None of the animals showed clinical signs of muscular disease. Muscle specimens were submitted to histological and enzymatic investigations. Gross pathology revealed a different grade of infiltration of adipose tissue, involving multiple or single muscles. The most affected regions were the ventral abdomen and the shoulders, especially the cutaneous muscles and the muscles of the thoracic group. Morphological staining revealed an infiltration of adipose tissue varying in distribution and severity, changes in muscle fibre size and increased number of fibres with centrally located nuclei, suggesting muscle degeneration–regeneration. Necrosis and non-suppurative inflammatory cells were also seen. Furthermore, proliferation of connective tissue and non-specific myopathic changes were present. Chemical and physical characteristics of the affected tissue were also evaluated. The authors discuss about the aetiopathogenesis and classification of this muscle disorder whose histological lesions were similar to those reported in human dystrophies.

Keywords

lipomatous myopathycattlepathologychemical–physical characteristics
Type
Behaviour, welfare and health
Information
animal , Volume 6 , Issue 11 , November 2012 , pp. 1839 - 1847
Copyright
Copyright © The Animal Consortium 2012

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