Austenaa, LM, Carlsen, H, Hollung, K, Blomhoff, HK and Blomhoff, R 2009. Retinoic acid dampens LPS-induced NF-kappa B activity results from human monoblasts and in vivo imaging of NF-kappa B reporter mice. The Journal of Nutritional Biochemistry 20, 726–734.
Baker, AK, Wang, R, Mackman, N and Luyendyk, JP 2009. Rapamycin enhances LPS induction of tissue factor and tumor necrosis factor-alpha expression in macrophages by reducing IL-10 expression. Molecular Immunology 46, 2249–2255.
Cario, E, Rosenberg, M, Brandwein, SL, Beck, PL, Reinecker, HC and Podolsky, DK 2000. Lipopolysaccharide activates distinct signaling pathways in intestinal epithelial cell lines expressing Toll-like receptors. Journal of Immunology 164, 966–972.
Cerutti, A and Rescigno, M 2008. The biology of intestinal immunoglobulin A responses. Immunity 28, 740–750.
Ci, X, Ren, R, Xu, K, Li, H, Yu, Q, Song, Y, Wang, D, Li, R and Deng, X 2010. Schisantherin A exhibits anti-inflammatory properties by down-regulating NF-kappa B and MAPK signaling pathways in lipopolysaccharide-treated RAW 264.7 cells. Inflammation 33, 126–136.
Dos Santos, S, Delattre, AI, De Longueville, F, Bult, H and Raes, M 2007. Gene expression profiling of LPS-stimulated murine macrophages and role of the NF-kappa B and PI3K/mTOR signaling pathways. Annals of the New York Academy of Sciences 1096, 70–77.
Duan, Y, Li, F, Li, Y, Tang, Y, Kong, X, Feng, Z, Anthony, TG, Watford, M, Hou, Y, Wu, G and Yin, Y 2016. The role of leucine and its metabolites in protein and energy metabolism. Amino Acids 48, 41–51.
Duchéne, S, Audouin, E, Crochet, S, Duclos, MJ, Dupont, J and Tesseraud, S 2008. Involvement of the ERK1/2 MAPK pathway in insulin-induced S6K1 activation in avian cells. Domestic Animal Endocrinology 34, 63–73.
Fielhaber, JA, Carroll, SF, Dydensborg, AB, Shourian, M, Triantafillopoulos, A, Harel, S, Hussain, SN, Bouchard, M, Qureshi, ST and Kristof, AS 2012. Inhibition of mammalian target of rapamycin augments lipopolysaccharide-induced lung injury and apoptosis. The Journal of Immunology 188, 4535–4542.
Ghosh, S, Tergaonkar, V, Rothlin, CV, Correa, RG, Bottero, V, Bist, P, Verma, IM and Hunter, T 2006. Essential role of tuberous sclerosis genes TSC1 and TSC2 in NF-kappaB activation and cell survival. Cancer Cell 10, 215–226.
Hou, YC, Chiu, WC, Yeh, CL and Yeh, SL 2012. Glutamine modulates lipopolysaccharide-induced activation of NF-κB via the Akt/mTOR pathway in lung epithelial cells. American Journal of Physiology. Lung Cellular and Molecular Physiology 302, L174–L183.
Huang, B, Xiao, D, Tan, B, Xiao, H, Wang, J, Yin, J, Duan, J, Huang, R, Yang, C and Yin, Y 2016. Chitosan oligosaccharide reduces intestinal inflammation that involves calcium-sensing receptor (CaSR) activation in lipopolysaccharide (LPS) -challenged piglets. Journal of Agricultural and Food Chemistry 64, 245–252.
Kogut, MH, Genovese, KJ, He, H and Arsenault, RJ 2016. AMPK and mTOR, sensors and regulators of immunometabolic changes during Salmonella infection in the chicken. Poultry Science 95, 345–353.
Krämer, S, Wang-Rosenke, Y, Scholl, V, Binder, E, Loof, T, Khadzhynov, D, Kawachi, H, Shimizu, F, Diekmann, F, Budde, K, Neumayer, HH and Peters, H 2008. Low-dose mTOR inhibition by rapamycin attenuates progression in anti-thy1-induced chronic glomerulosclerosis of the rat. American journal of physiology. Renal Physiology 294, F440–F449.
Lebman, DA, Lee, FD and Coffman, RL 1990. Mechanism for transforming growth factor beta and IL-2 enhancement of IgA expression in lipopolysaccharide-stimulated B cell cultures. The Journal of Immunology 144, 952–959.
Lin, HY, Chang, KT, Hung, CC, Kuo, CH, Hwang, SJ, Chen, HC, Hung, CH and Lin, SF 2014. Effects of the mTOR inhibitor Rapamycin on Monocyte-Secreted Chemokines. BMC Immunology 15, 37.
Liu, D, Li, P, Song, S, Liu, Y, Wang, Q, Chang, Y, Wu, Y, Chen, J, Zhao, W, Zhang, L and Wei, W 2012. Pro-apoptotic effect of Epigallo-catechin-3-gallate on B lymphocytes through regulating BAFF/PI3K/Akt/mTOR signaling in rats with collagen-induced arthritis. European Journal of Pharmacology 690, 214–225.
Liu, DY, Wang, S, Jiang, T and Ding, P 2013. TNF-ɑ mediated secretory component is positively regulated by PI3K/AKT/mTOR in CACO-2 cells. Bangladesh Journal of Medical Biochemistry 32, 116–120.
Liu, SQ, Zhao, JP, Fan, XX, Liu, GH, Jiao, HC, Wang, XJ, Sun, SH and Lin, H 2015. Rapamycin, a specific inhibitor of the target of rapamycin complex 1, disrupts intestinal barrier integrity in broiler chicks. Journal of Animal Physiology and Animal Nutrition 100, 323–330.
Lu, YC, Yeh, WC and Ohashi, PS 2008. LPS/TLR4 signaling transduction pathway. Cytokine 42, 145–151.
Macpherson, AJ, Gatto, D, Sainsbury, E, Harriman, GR, Hengartner, H and Zinkernagel, RM 2000. A primitive T cell-independent mechanism of intestinal mucosal IgA responses to commensal bacteria. Science 288, 2222–2226.
Mendes, SD, Candi, A, Vansteenbrugge, M, Pignon, MR, Bult, H, Boudjeltia, KZ, Munaut, C and Raes, M 2009. Microarray analyses of the effects of NF-κB or PI3 K pathway inhibitors on the LPS-induced gene expression profile in RAW264.7 cells Synergistic effects of rapamycin on LPS-induced MMP9-over-expression. Cell Signaling 21, 1109–1122.
Moraes, ML, Ribeiro, AM, Santin, E and Klasing, KC 2016. Effects of conjugated linoleic acid and lutein on the growth performance and immune response of broiler chickens. Poultry Science 95, 237–246.
Nemazee, D, Gavin, A, Hoebe, K and Beutler, B 2006. Immunology, Toll-like receptors and antibody responses. Nature 441, E4.
Rhoads, JM, Corl, BA, Harrell, R, Niu, X, Gatlin, L, Phillips, O, Blikslager, A, Moeser, A, Wu, G and Odle, J 2007. Intestinal ribosomal p70 (S6K) signaling is increased in piglet rotavirus enteritis. American journal of physiology. Gastrointestinal and Liver Physiology 292, G913–G922.
Sampson, LL, Davis, AK, Grogg, MW and Zheng, Y 2016. mTOR disruption causes intestinal epithelial cell defects and intestinal atrophy post injury in mice. FASEB Journal 30, 1263–1275.
Sarbassov, DD, Ali, SM and Sabatini, DM 2005. Growing roles for the mTOR pathway. Current Opinion in Cell Biology 17, 596–603.
Schaeffer, V, Arbabi, S, Garcia, IA, Knoll, ML, Cuschieri, J, Bulger, EM and Maier, RV 2011. Role of the mTOR pathway in LPS-activated monocytes, influence of hypertonic saline. The Journal of Surgical Research 171, 769–776.
Sitia, R, Neuberger, MS and Milstein, C 1987. Regulation of membrane IgM expression in secretory B cells: translational and post-translational events. The EMBO Journal 6, 3969–3977.
Tan, B, Yin, YL, Kong, XF, Li, P, Li, XL, Gao, HJ, Li, XG, Huang, RL and Wu, GY 2010. L-Arginine stimulates proliferation and prevents endotoxin-induced death of intestinal cells. Amino Acids 38, 1227–1235.
To, KK, Lau, CC, Woo, PC, Lau, SK, Chan, JF, Chan, KH, Zhang, AJ, Chen, H and Yuen, KY 2016. Human H7N9 virus induces a more pronounced pro-inflammatory cytokine but an attenuated interferon response in human bronchial epithelial cells when compared with an epidemiologically-linked chicken H7N9 virus. Virology Journal. 13, 42.
Wang, XJ, Yang, X, Wang, RX, Jiao, HC, Song, ZG and Lin, H 2016. Leucine alleviates dexamethasone-induced suppression of muscle protein synthesis via synergy involvement of mTOR and AMPK pathways[J]. Bioscience Reports 36, e00346.
Watanabe, H, Kobayashi, K and Isayama, Y 1975. Peculiar secretory IgA system identified in chickens. II. Identification and distribution of free secretory component and immunoglobulins of IgA, IgM, and IgG in chicken external secretions. The Journal of Immunology 115, 998–1001.
Weichhart, T, Costantino, G, Poglitsch, M, Rosner, M, Zeyda, M, Stuhlmeier, KM, Kolbe, T, Stulnig, TM, Hörl, WH, Hengstschläger, M, Müller, M and Säemann, MD 2008. The TSC-mTOR signaling pathway regulates the innate inflammatory response. Immunity 29, 565–577.
Wessels, AG, Kluge, H, Hirche, F, Kiowski, A, Schutkowski, A, Corrent, E, Bartelt, J, König, B and Stangl, G 2016. High leucine diets stimulate cerebral branched-chain amino acid degradation and modify serotonin and ketone body concentrations in a pig model. PloS ONE 11, e0150376.