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Influence of colostrum intake on piglet survival and immunity

  • N. Devillers (a1) (a2), J. Le Dividich (a1) (a2) and A. Prunier (a1) (a2)


Colostrum intake from birth to 24 h after the onset of parturition (T24) was estimated for 526 piglets from 40 litters. Plasma concentrations of immunoglobulin G (IgG), lactate, glucose and cortisol were determined at T24 for six piglets per litter. Plasma IgG concentration was also assayed at weaning (28 days) on the same piglets. Rectal temperature was measured at T24 on all piglets. Mortality was recorded until weaning and comparisons were made between piglets that died before weaning and those that were still alive at weaning. The piglets that died before weaning had lower birth weight, lower colostrum intake, lower weight gain between birth and T24, and had a lower rectal temperature, higher plasma cortisol concentration and lower plasma IgG and glucose concentrations at T24 than piglets still alive at weaning. In addition, a higher proportion of piglets that died before weaning had difficulty taking their first breath after birth and were affected by splayleg. Considering all piglets, colostrum intake was positively related to rectal temperature and plasma glucose concentration and negatively related to plasma cortisol concentration at T24. Plasma IgG concentration at T24 was explained by colostrum intake, IgG concentration in the ingested colostrum, birth weight and birth rank (P < 0.0001). Plasma IgG concentration at weaning was related to plasma IgG concentration at T24 (r = 0.54; P < 0.0001) and to colostrum intake (r = 0.32; P < 0.0001). Finally, body weight was explained by colostrum intake, birth weight and age until 6 weeks of age (P < 0.0001). These results show that colostrum intake is the main determinant of piglet survival through provision of energy and immune protection and has potential long-term effects on piglet growth and immunity.



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Association of Official Analytical Chemists 1990. Official methods of analysis. AOAC, Washington, DC, USA.
Bate, LA, Hacker, RR 1985. The influence of the sow's adrenal activity on the ability of the piglet to absorb IgG from colostrum. Canadian Journal of Animal Science 65, 7785.
Bland, IM, Rooke, JA, Bland, VC, Sinclair, AG, Edwards, SA 2003. Appearance of immunoglobulin G in the plasma of piglets following intake of colostrum, with or without a delay in sucking. Animal Science 77, 277286.
Curtis, J, Bourne, FJ 1973. Half-lives of immunoglobulins IgG, IgA and IgM in the serum of new-born pigs. Immunology 24, 147155.
de Passillé, AM, Rushen, J 1989. Using early suckling behavior and weight gain to identify piglets at risk. Canadian Journal of Animal Science 69, 535544.
Devillers, N, Farmer, C, Mounier, AM, Le Dividich, J, Prunier, A 2004a. Hormones, IgG and lactose changes around parturition in plasma, and colostrum or saliva of multiparous sows. Reproduction Nutrition Development 44, 381396.
Devillers, N, van Milgen, J, Prunier, A, Le Dividich, J 2004b. Estimation of colostrum intake in the neonatal pig. Animal Science 78, 305313.
Devillers, N, Farmer, C, Le Dividich, J, Prunier, A 2007. Variability of colostrum yield and colostrum intake in pigs. Animal 1, 10331041.
Edwards, SA 2002. Perinatal mortality in the pig: environmental or physiological solutions? Livestock Production Science 78, 312.
Frenyó, VL, Pethes, G, Antal, T, Szabó, I 1981. Changes in colostral and serum IgG content in swine in relation to time. Veterinary Research Communications 4, 275282.
Gardner, IA, Hird, DW, Franti, CE 1989. Neonatal survival in swine: effects of low birth weight and clinical disease. American Journal of Veterinary Research 50, 792797.
Gordon, GO, Whittier, EO 1965. Proteins of milk. In Fundamentals of dairy chemistry (ed. BH Webb and AH Johnson), pp. 5490. Avi Publishing Company, Westport, CT, USA.
Gourmelen, C, Marouby, H 2007. La situation économique des élevages de porcs français: résultats 2006. Techni-Porc 30, 313.
Herpin, P, Le Dividich, J, van Os, M 1992. Contribution of colostral fat to thermogenesis and glucose homeostasis in the newborn pig. Journal of Developmental Physiology 17, 133141.
Herpin, P, Le Dividich, J, Hulin, JC, Fillaut, M, De Marco, F, Bertin, R 1996. Effects of the level of asphyxia during delivery on viability at birth and early postnatal vitality of newborn pigs. Journal of Animal Science 74, 20672075.
Herpin, P, Hulin, JC, Le Dividich, J, Fillaut, M 2001. Effect of oxygen inhalation at birth on the reduction of early postnatal mortality in pigs. Journal of Animal Science 79, 510.
Herpin, P, Damon, M, Le Dividich, J 2002. Development of thermoregulation and neonatal survival in pigs. Livestock Production Science 78, 2545.
Jensen, AR, Elnif, J, Burrin, DG, Sangild, PT 2001. Development of intestinal immunoglobulin absorption and enzyme activities in neonatal pigs is diet dependent. Journal of Nutrition 131, 32593265.
Klobasa, F, Werhahn, E, Butler, JE 1981. Regulation of humoral immunity in the piglet by immunoglobulins of maternal origin. Research in Veterinary Science 31, 195206.
Klobasa, F, Werhahn, E, Butler, JE 1987. Composition of sow milk during lactation. Journal of Animal Science 64, 14581466.
Le Cozler, Y, Guyomarc'h, C, Pichodo, X, Quinio, PY, Pellois, H 2002. Factors associated with stillborn and mummified piglets in high-prolific sows. Animal Research 51, 261268.
Le Dividich, J, Noblet, J 1981. Colostrum intake and thermoregulation in the neonatal pig in relation to environmental temperature. Biology of the Neonate 40, 167174.
Le Dividich, J, Rooke, JA, Herpin, P 2005. Nutritional and immunological importance of colostrum for the new-born pig. Journal of Agricultural Science 143, 469485.
Lepine, AJ, Boyd, RD, Welch, J 1989. Effect of colostrum intake on plasma glucose, non-esterified fatty acid and glucoregulatory hormone patterns in the neonatal pig. Domestic Animal Endocrinology 6, 231241.
Milligan, BN, Fraser, D, Kramer, DL 2002. Within-litter birth weight variation in the domestic pig and its relation to pre-weaning survival, weight gain, and variation in weaning weights. Livestock Production Science 76, 181191.
Pettigrew, JE, Sower, AF, Cornelius, SG, Moser, RL 1985. A comparison of isotope dilution and weigh-suckle-weigh methods for estimating milk intake by pigs. Canadian Journal of Animal Science 65, 989992.
Quiniou, N, Dagorn, J, Gaudré, D 2002. Variation of piglets’ birth weight and consequences on subsequent performance. Livestock Production Science 78, 6370.
Randall, GC 1972. Observations on parturition in the sow. II. Factors influencing stillbirth and perinatal mortality. Veterinary Record 90, 183186.
Rooke, JA, Bland, IM 2002. The acquisition of passive immunity in the new-born piglet. Livestock Production Science 78, 1323.
Rooke, JA, Carranca, C, Bland, IM, Sinclair, AG, Ewen, M, Bland, VC, Edwards, SA 2003. Relationships between passive absorption of immunoglobulin G by the piglet and plasma concentrations of immunoglobulin G at weaning. Livestock Production Science 81, 223234.
Rydhmer, L 1992. Relations between piglet weights and survival. In Neonatal survival and growth (ed. MA Varley, PEV Williams and TLJ Lawrence), pp. 183184. British Society of Animal Production, Edinburgh, UK.
SAS 2002. Statistical Analysis System, release 9.1. SAS Institute Inc., Cary, NC, USA.
Salmon, H, Berri, M, Gerdts, V, Meurens, F 2009. Humoral and cellular factors of maternal immunity in swine. Developmental and Comparative Immunology 33, 384393.
Sangild, PT, Fowden, AL, Trahair, JF 2000. How does the foetal gastrointestinal tract develop in preparation for enteral nutrition after birth? Livestock Production Science 66, 141150.
Thompson, BK, Fraser, D 1988. Variation in piglet weights: weight gains in the first days after birth and their relationship with later performance. Canadian Journal of Animal Science 68, 581590.
Tuboly, S, Bernath, S, Glavits, R, Medveczky, I 1988. Intestinal absorption of colostral lymphoid cells in newborn piglets. Veterinary Immunology and Immunopathology 20, 7585.
Tuchscherer, M, Puppe, B, Tuchscherer, A, Tiemann, U 2000. Early identification of neonates at risk: traits of newborn piglets with respect to survival. Theriogenology 54, 371388.
Tyler, JW, Cullor, JS, Thurmond, MC, Douglas, VL, Parker, KM 1990. Immunologic factors related to survival and performance in neonatal swine. American Journal of Veterinary Research 51, 14001406.
Weary, DM, Pajor, EA, Thompson, BK, Fraser, D 1996. Risky behaviour by piglets: a trade off between feeding and risk of mortality by maternal crushing? Animal Behaviour 51, 619624.
Werhahn, E, Klobasa, F, Butler, JE 1981. Investigation of some factors which influence the absorption of IgG by the neonatal piglet. Veterinary Immunology and Immunopathology 2, 3551.
Xu, RJ, Wang, F, Zhang, SH 2000. Postnatal adaptation of the gastrointestinal tract in neonatal pigs: a possible role of milk-borne growth factors. Livestock Production Science 66, 95107.
Zaleski, HM, Hacker, RR 1993. Variables related to the progress of parturition and probability of stillbirth in swine. Canadian Veterinary Journal 34, 109113.


Influence of colostrum intake on piglet survival and immunity

  • N. Devillers (a1) (a2), J. Le Dividich (a1) (a2) and A. Prunier (a1) (a2)


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