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Effects of dietary protein supply, weaning age and experimental enterotoxigenic Escherichia coli infection on newly weaned pigs: performance

Published online by Cambridge University Press:  13 May 2008

I. J. Wellock ,
P. D. Fortomaris ,
J. G. M. Houdijk  and
I. Kyriazakis
I. J. Wellock*
Affiliation:
Animal Nutrition and Health Department, Scottish Agricultural College, West Mains Road, Edinburgh, EH9 3JG, UK
P. D. Fortomaris
Affiliation:
Department of Animal Production, School of Veterinary Medicine, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece
J. G. M. Houdijk
Affiliation:
Animal Nutrition and Health Department, Scottish Agricultural College, West Mains Road, Edinburgh, EH9 3JG, UK
I. Kyriazakis
Affiliation:
Animal Nutrition and Health Department, Scottish Agricultural College, West Mains Road, Edinburgh, EH9 3JG, UK Faculty of Veterinary Medicine, University of Thessaly, Trikalon 224, 43100 Karditsa, Greece
*
E-mail: ian.wellock@abagri.com
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Abstract

An experiment was conducted to investigate the effects of post-weaning dietary protein supply and weaning age on the performance of pigs in the absence of in-feed antimicrobial growth promoters (AGP) when artificially challenged with enterotoxigenic Escherichia coli (ETEC), a pathogen associated with post-weaning colibacillosis (PWC). The experiment consisted of a complete 2 × 2 × 2 factorial combination of two weaning ages (4 v. 6 week), two levels of dietary protein (H, 230 g CP/kg v. L, 130 g CP/kg) and challenge with ETEC (+ v. −). An additional four treatments were added to test for the effects of protein source (DSMP, dried skimmed milk powder v. SOYA, soybean meal) and AGP inclusion (yes v. no) on challenged pigs of both weaning ages. At weaning (day 0), pigs were assigned to one of the experimental treatments for 2 weeks. On day 14 post-weaning, the same standard grower ration was fed to all animals until 10 weeks of age. On day 3 post weaning, challenged pigs were administered per os with 109 cfu ETEC. The ETEC challenge had a detrimental short-term effect on performance, decreasing average daily gain (ADG) (days 3 to 6; P = 0.014) in both 4- and 6-week weaned animals. Compared with their non-infected counterparts, challenged 4-week weaned pigs on the H diet demonstrated a larger decrease in ADG immediately post infection than those on the L diet, −42% and −25%, respectively (P = 0.088). This effect was smaller in the 6-week weaned pigs, −26% and −19% for the H and L diets, respectively. Pigs fed SOYA had lower (P < 0.001) daily intake and ADG (day 0 to 14) than those fed DSMP, with 6-week weaned pigs being affected to a greater extent than 4-week weaned pigs. In the absence of AGP, increasing weaning age and decreasing dietary protein level, especially in earlier weaned pigs, may help to minimise the effects of PWC on performance, particularly in sub-optimal environments.

Keywords

intakepigspost-weaning colibacillosisproteinweaning age
Type
Full Paper
Information
animal , Volume 2 , Issue 6 , June 2008 , pp. 825 - 833
Copyright
Copyright © The Animal Consortium 2008

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References

Bach Knudsen, KE 1997. Carbohydrate and lignin contents of plant materials used in animal feeding. Animal Feed Science and Technology 67, 319–338.CrossRefGoogle Scholar
Barton, MD 1999. The down-side of antibiotic use in pig production: The effect of antibiotic resistance of enteric bacteria. In Manipulating Pig Production VII (ed. PD Carnwell), pp. 194–199. Australasian Pig Science Association, Victoria, Australia.Google Scholar
Edwards, S 2004. Effect of the weaning age on post weaning performance in piglets without using antibiotic growth promoters. In Proceedings of the World Nutrition Forum 2004, pp. 16–19. Salzburg, Austria.Google Scholar
English, PR, Robb, CM, Dias, MFM 1980. Evaluation of creep feed using a highly digestible diet for litters weaned at 4 weeks of age. Animal Production 30, 496 (abstract).Google Scholar
Hampson, DJ 1994. Postweaning E. coli diarrhoea in pigs. In E. coli in Domestic Animals and Humans (ed. CL Gyles), pp. 171–191. CAB International, Wallingford, UK.Google Scholar
Hopwood, DE, Pethick, DW, Pluske, JR, Hampson, DJ 2004. Addition of pearl barley to a rice-based diet for newly weaned piglets increases the viscosity of the intestinal contents, reduces starch digestibility and exacerbates post-weaning colibacillosis. British Journal of Nutrition 92, 419–427.CrossRefGoogle ScholarPubMed
Houdijk, JGM, Anderson, DH, Kyriazakis, I 2005. Induction of experimental sub-clinical post-weaning colibacillosis in pigs. In Proceedings of the British Society of Animal Science, p. 84. York, UK (abstract).Google Scholar
Krsnik, B, Yammine, R, Pavicic, Z, Balennovic, T, Njari, B, Vrbanac, I, Valpotic, I 1999. Experimental model of enterotoxigenic E. coli infection in pigs: potential for an early recognition of colibacillosis by monitoring of behavior. Comparative Immunology, Microbiology and Infectious Diseases 22, 261–273.CrossRefGoogle ScholarPubMed
Lawlor, PG, Lynch, PB, Caffrey, PJ, O’Doherty, JV 2002. Effect of pre- and post-weaning management on subsequent pig performance to slaughter and carcass quality. Animal Science 75, 245–256.CrossRefGoogle Scholar
Madec, F, Bridoux, N, Bounaix, S, Cariolet, R, Duval-Iflah, Y, Hampson, DJ, Jestin, A 2000. Experimental models of porcine post-weaning colibacillosis and their relationship to post-weaning diarrhoea and digestive disorders as encountered in the field. Veterinary Microbiology 72, 295–310.CrossRefGoogle ScholarPubMed
McDonald, DE, Pethick, DW, Pluske, JR, Hampson, DJ 1999. Adverse effects of soluble nonstarch polysaccharide (guar gum) on piglet growth and experimental colibacillosis immediately after weaning. Research in Veterinary Science 67, 245–250.CrossRefGoogle ScholarPubMed
Montagne, L, Cavaney, FS, Hampson, DJ, Lalles, JP, Pluske, JR 2004. Effect of diet composition on postweaning colibacillosis in piglets. Journal of Animal Science 82, 2364–2374.CrossRefGoogle ScholarPubMed
Nabuurs, MJA 1995. Microbiological, structural and functional changes of the small intestine of pigs at weaning. Pig News and Information 16, 93–97.Google Scholar
Nabuurs, MJA, Hoogendoorn, A, van Zijderveld-van Bemmel, A 1996. Effect of supplementary feeding during the sucking period on net absorption from the small intestine of weaned pigs. Research in Veterinary Science 61, 72–77.CrossRefGoogle ScholarPubMed
Nyachoti, CM, Omogbenigun, FO, Rademacher, M, Blank, G 2006. Performance responses and indicators of gastrointestinal health in early-weaned pigs fed low-protein amino-acid supplemented diets. Journal of Animal Science 84, 125–134.CrossRefGoogle ScholarPubMed
Okai, DB, Aherne, FX, Hardin, RT 1976. Effects of creep and starter composition on the feed intake and performance of young pigs. Canadian Journal of Animal Science 56, 573–586.CrossRefGoogle Scholar
Pluske, JR, Williams, IH, Aherne, FX 1996. Maintenance of villous height and crypt depth in piglets by providing continuous nutrition after weaning. Animal Science 62, 144.Google Scholar
Pluske, JR, Hampson, DJ, Williams, IH 1997. Factors influencing the structure and function of the small intestine in the weaned pig: a review. Livestock Production Science 51, 215–236.CrossRefGoogle Scholar
Pluske, JR, Black, B, Pethick, DW, Mullan, BP, Hampson, DJ 2003. Effects of different sources and levels of dietary fibre in diets on performance, digesta characteristics and antibiotic treatment of pigs after weaning. Animal Feed Science and Technology 107, 129–142.CrossRefGoogle Scholar
Porter, P, Kenworthy, R 1969. A study of intestinal and urinary amines in pig in relation to weaning. Research in Veterinary Science 10, 440–447.CrossRefGoogle ScholarPubMed
Prohászka, L, Baron, F 1980. The predisposing role of high dietary protein supplies in enteropathogenic E. coli infections of weaned pigs. Zentralblatt für Veterinärmedizin 27, 222–232.CrossRefGoogle ScholarPubMed
Genstat 5 for Windows (release 4.2, service pack 2) 2001. Lawes Agricultural Trust, Rothamsted, UK.Google Scholar
Sarmiento, JI, Casey, TA, Moon, HW 1988. Postweaning diarrhea in swine: Experimental model of enterotoxigenic E. coli infection. American Journal of Veterinary Research 49, 1154–1159.Google Scholar
Wellock, IJ, Fortomaris, PD, Houdijk, JGM, Kyriazakis, I 2006. The effect of dietary protein supply on the performance and risk of post-weaning enteric disorders in newly weaned pigs. Animal Science 82, 327–335.CrossRefGoogle Scholar
Wellock IJ, Fortomaris PD, Houdijk JGM, and Kyriazakis I 2008. Effects of dietary protein supply, weaning age and experimental enterotoxigenic Escherichia coli infection on newly weaned pigs: health. Animal 2, 834–842.CrossRefGoogle Scholar