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Effects of concentrate type and chromium propionate on insulin sensitivity, productive and reproductive parameters of lactating dairy cows consuming excessive energy

  • T. Leiva (a1), R. F. Cooke (a2), A. P. Brandão (a1) (a2), U. Pardelli (a1), R. O. Rodrigues (a1), F. N. Corrá (a1) and J. L. M. Vasconcelos (a1)...

Abstract

This experiment compared insulin sensitivity parameters, milk production and reproductive outcomes in lactating dairy cows consuming excessive energy, and receiving in a 2×2 factorial arrangement design: (1) concentrate based on ground corn (CRN; n=13) or citrus pulp (PLP; n=13), and (2) supplemented (n=14) or not (n=12) with 2.5 g/day of chromium (Cr)-propionate. During the experiment (day 0 to 182), 26 multiparous, non-pregnant, lactating Gir×Holstein cows (initial days in milk=80±2) were offered corn silage for ad libitum consumption, and individually received concentrate formulated to allow diets to provide 160% of their daily requirements of net energy for lactation. Cow BW and body condition score (BCS) were recorded weekly. Milk production was recorded daily and milk samples collected weekly. Blood samples were collected weekly before the morning concentrate feeding. Glucose tolerance tests (GTT; 0.5 g of glucose/kg of BW) were performed on days −3, 60, 120 and 180. Follicle aspiration for in vitro embryo production was performed via transvaginal ovum pick-up on days −1, 82 and 162. No treatment differences were detected (P⩾0.25) for BW and BCS change during the experiment. Within weekly blood samples, concentrations of serum insulin and glucose, as well as insulin : glucose ratio were similar among treatments (P⩾0.19), whereas CRN had less (P<0.01) non-esterified fatty acid concentrations compared with PLP (0.177 v. 0.215 mmol/l; SEM=0.009). During the GTT, no treatment differences were detected (P⩾0.16) for serum glucose concentration, glucose clearance rate, glucose half-life and insulin : glucose ratio. Serum insulin concentrations were less (P=0.04) in CRN supplemented with Cr-propionate compared with non-supplemented CRN (8.2 v. 13.5 µIU/ml, respectively; SEM=1.7), whereas Cr-propionate supplementation did not impact (P=0.70) serum insulin within PLP cows. Milk production, milk fat and solid concentrations were similar (P⩾0.48) between treatments. However, CRN had greater (P<0.01) milk protein concentration compared with PLP (3.54% v. 3.14%, respectively; SEM=0.08). No treatment differences were detected (P⩾0.35) on number of viable oocytes collected and embryos produced within each aspiration. In summary, feeding a citrus pulp-based concentrate to lactating dairy cows consuming excessive energy did not improve insulin sensitivity, milk production and reproductive outcomes, whereas Cr-propionate supplementation only enhanced insulin sensitivity in cows receiving a corn-based concentrate during a GTT.

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Adamiak, SJ, Mackie, K, Watt, RG, Webb, R and Sinclair, KD 2005. Impact of nutrition on oocyte quality: cumulative effects of body composition and diet leading to hyperinsulinemia in cattle. Biology of Reproduction 73, 918926.
AOAC 1999. Official method of analysis, 16th edition. Association of Official Analytical Chemsts, Arlington, VA, USA.
Baruselli, PS, Vieira, LM, Sá Filho, MF, Mingoti, RD, Ferreira, RM, Chiaratti, MR, Oliveira, LH, Sales, JN and Sartori, R 2016. Associations of insulin resistance later in lactation on fertility of dairy cows. Theriogenology 86, 263269.
Belibasakis, NG and Tsirgogianni, D 1996. Effects of dried citrus pulp on milk yield, milk composition and blood components of dairy cows. Animal Feed Science and Technology 60, 8792.
Bergman, EN 1990. Energy contributions of volatile fatty acids from the gastrointestinal tract in various species. Physiology Reviews 70, 567590.
Bernhard, BC, Burdick, NC, Rathmann, RJ, Carroll, JA, Finck, DN, Jennings, MA, Young, TR and Johnson, BJ 2012. Chromium supplementation alters both glucose and lipid metabolism in feedlot cattle during the receiving period. Journal of Animal Science 90, 48574865.
Bickerstaffe, R, Annison, EF and Linzell, JL 1974. The metabolism of glucose, acetate, lipids and amino acids in lactating dairy cows. The Journal of Agricultural Science 82, 7185.
Bilby, TR, Block, J, do Amaral, BC, Sa Filho, O, Silvestre, FT, Hansen, PJ, Staples, CR and Thatcher, WW 2006. Effects of dietary unsaturated fatty acids on oocyte quality and follicular development in lactating dairy cows in summer. Journal of Dairy Science 89, 38913903.
Bryan, MA, Socha, MT and Tomlinson, DJ 2004. Supplementing intensively grazed late-gestation and early-lactation dairy cattle with chromium. Journal of Dairy Science 87, 42694277.
Bunting, LD, Fernandez, JM, Thompson, DL and Southern, LL 1994. Influence of chromium picolinate on glucose usage and metabolic criteria in growing Holstein calves. Journal of Animal Science 72, 15911599.
Cabrita, ARJ, Bessa, RJB, Alves, SP, Dewhurst, RJ and Fonseca, AJM 2007. Effects of dietary protein and starch on intake, milk production, and milk fatty acid profiles of dairy cows fed corn silage-based diets. Journal of Dairy Science 90, 14291439.
Grummer, RR 1995. Impact of changes in organic nutrient metabolism on feeding the transition dairy cow. Journal of Animal Science 73, 28202833.
Grünberg, W, Donkin, SS and Constable, PD 2011. Periparturient effects of feeding a low dietary cation-anion difference diet on acid-base, calcium, and phosphorus homeostasis and on intravenous glucose tolerance test in high-producing dairy cows. Journal of Dairy Science 94, 727745.
Hayirli, A, Bremmer, DR, Bertics, SJ, Socha, MT and Grummer, RR 2001. Effect of chromium supplementation on production and metabolic parameters in periparturient dairy cows. Journal of Dairy Science 84, 12181230.
Huntington, GB 1997. Starch utilization by ruminants: from basics to the bunk. Journal of Animal Science 75, 852867.
LeBlanc, S 2010. Monitoring metabolic health of dairy cattle in the transition period. Journal of Reproduction and Development 56, S29S35.
Leiva, E, Hall, MB and Van Horn, HH 2000. Performance of dairy cattle fed citrus pulp or corn products as sources of neutral detergent-soluble carbohydrates. Journal of Dairy Science 83, 28662875.
Leiva, T, Cooke, RF, Aboin, AC, Drago, FL, Gennari, R and Vasconcelos, JLM 2014. Effects of excessive energy intake and supplementation with chromium propionate on insulin resistance parameters in non-lactating dairy cows. Journal of Animal Science 92, 775782.
Leiva, T, Cooke, RF, Brandão, AP, Aboin, AC, Ranches, J and Vasconcelos, JLM 2015. Effects of excessive energy intake and supplementation with chromium propionate on insulin resistance parameters in lactating dairy cows. Livestock Science 180, 121128.
Lemosquet, S, Rigout, S, Bach, A, Rulquin, H and Blum, JW 2004. Glucose metabolism in lactating cows in response to isoenergetic infusions of propionic acid or duodenal glucose. Journal of Dairy Science 87, 17671777.
McGuire, MA, Griinari, JM, Dwyer, DA and Bauman, DE 1995. Role of insulin in the regulation of mammary synthesis of fat and protein. Journal of Dairy Science 78, 816824.
Mertz, W 1992. Chromium: history and nutritional importance. Biological Trace Element Research 32, 38.
Moller, DE and Flier, JS 1991. Insulin resistance – mechanisms, syndromes, and implications. New England Journal of Medicine 325, 938948.
National Research Council (NRC) 2001. Nutrient Requirements of Dairy Cattle. National Academic Press, Washington, DC, USA.
Nussey, SS and Whitehead, SA 2001. Endocrinology: an integrated approach. BIOS Scientific, Oxford, UK.
Perseghin, G, Caumo, A, Caloni, M, Testolin, G and Luzi, L 2001. Incorporation of the fasting plasma FFA concentration into QUICKI improves its association with insulin sensibility in non-obese individuals. The Journal of Clinical Endocrinology and Metabolism 86, 47764781.
Soltan, MA 2010. Effect of dietary chromium supplementation on productive and reproductive performance of early lactating dairy cows under heat stress. Journal of Animal Physiology and Animal Nutrition 94, 264272.
Sumner, JM, Valdez, F and McNamara, JP 2007. Effects of chromium propionate on response to an intravenous glucose tolerance test in growing Holstein heifers. Journal of Dairy Science 90, 34673474.
Tvedten, H, Kopcia, M and Haines, C 2000. Mixed venous and arterial blood in bovine coccygeal vessel samples for blood gas analysis. Veterinary Clinical Pathology 29, 46.
Van Saun, RJ and Sniffen, CJ 1996. Nutritional management of the pregnant dairy cow to optimize health, lactation and reproductive performance. Animal Feed Science and Technology 59, 1326.
Vincent, JB 2001. The bio-inorganic chemistry of chromium (III). Polyhedron 20, 126.
Wellen, KE and Hotamisligil, GS 2005. Inflammation, stress, and diabetes. The Journal of Clinical Investigation 115, 11111119.
Wildman, EE, Jones, GM, Wagner, PE, Boman, RL, Troutt, HF and Lesch, TN 1982. A dairy cow body condition scoring system and its relationship to selected production characteristics. Journal of Dairy Science 65, 495501.
Zhao, FQ, Dixon, WT and Kennelly, JJ 1996. Localization and gene expression of glucose transporters in bovine mammary gland. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology 115, 127134.

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