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Chicken lines divergent for low or high abdominal fat deposition: a relevant model to study the regulation of energy metabolism

  • E. Baéza (a1) and E. Le Bihan-Duval (a1)

Abstract

Divergent selection of chickens for low or high abdominal fat (AF) but similar BW at 63 days of age was undertaken in 1977. The selection programme was conducted over seven successive generations. The difference between lines was then maintained constant at about twice the AF in the fat line as in the lean line. The aims of the first studies on these divergent chicken lines were to describe the growth, body composition and reproductive performance in young and adult birds. The lines were then used to improve the understanding of the relationship between fatness and energy and protein metabolism in the liver, muscle and adipose tissues, as well as the regulation of such metabolism at hormonal, gene and hypothalamic levels. The effects on muscle energy metabolism in relation to meat quality parameters were also described. This paper reviews the main results obtained with these lines.

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Abasht, B, Pitel, F, Lagarrigue, S, Le Bihan-Duval, E, Le Roy, P, Demeure, O, Vignoles, F, Simon, J, Cogburn, L, Aggrey, S, Vignal, A, Douaire, M 2006. Fatness QTL on chicken chromosome 5 and interaction with sex. Genetics, Selection and Evolution 38, 297311.
Alleman, F, Michel, J, Chagneau, AM, Leclercq, B 1999a. Comparative responses of genetically lean and fat broiler chickens to dietary threonine concentration. British Poultry Science 40, 485490.
Alleman, F, Michel, J, Chagneau, AM, Leclercq, B 2000. The effects of dietary protein independent of essential amino acids on growth and body composition in genetically lean and fat chickens. British Poultry Science 41, 214218.
Alleman, F, Bordas, A, Caffin, JP, Daval, S, Diot, C, Douaire, M, Fraslin, JM, Lagarrigue, S, Leclercq, B 1999b. L'engraissement chez le poulet: aspects métaboliques et génétiques. INRA Productions Animales 12, 257264.
Assaf, S, Lagarrigue, S, Daval, S, Sansom, M, Leclercq, B, Michel, JL, Pitel, F, Alizadeh, M, Vignal, A, Douaire, M 2004. Genetic linkage and expression analysis of SREBP and lipogenic genes in fat and lean chicken. Comparative Biochemistry and Physiology B 137, 433441.
Beccavin, C, Chevalier, B, Simon, J, Duclos, MJ 1999. Circulating insulin-like growth factors (IGF-I and -II) and IGF binding proteins in divergently selected fat or lean chickens: effect of prolonged fasting. Growth Hormone and IGF Research 9, 187194.
Bernarczyk, MF, Simon, J, Ferre, R, Leclercq, B 1984. Effets de la lumière sur le développement embryonnaire dans deux lignées de poulets rendus maigres ou gras par selection. Reproduction, Nutrition et Développement 24, 235238.
Berri, C, Le Bihan-Duval, E, Baéza, E, Chartrin, P, Millet, N, Bordeau, T 2005. Effect of selection for or against abdominal fatness on muscle and meat characteristics of broilers. Proceedings of XVII WPSA European Symposium on the Quality of Poultry Meat, Doorwerth, The Netherlands, 23-26/05/05, pp. 266–270.
Bourneuf, E, Hérault, F, Chicault, C, Carre, W, Assaf, S, Monnier, A, Mottier, S, Lagarrigue, S, Douaire, M, Mosser, J, Diot, C 2006. Microarray analysis of differential gene expression in the liver of lean and fat chickens. Gene 372, 162170.
Buyse, J, Vanderpooten, A, Leclercq, B, Berghman, LR, Decuypere, E 1994. Pulsatility of plasma growth-hormone and hepatic growth-hormone receptor characteristics of broiler-chickens divergently selected for abdominal fat-content. British Poultry Science 35, 145152.
Byerly, MS, Simon, J, Le Bihan-Duval, E, Duclos, MJ, Cogburn, LA, Porter, TE 2009. Effects of BDNF, T3 and corticosterone on expression of the hypothalamic obesity gene network in vivo and in vitro. American Journal of Physiology – Regulatory, Integrative and Comparative Physiology 296, R1180R1189.
Byerly, MS, Simon, J, Cogburn, LA, Le Bihan-Duval, E, Duclos, MJ, Aggray, S, Porter, TE 2010. Transcriptional profiling of hypothalamus during development of adiposity in genetically selected fat and lean chickens. Physiology Genomics 42, 157167.
Cahaner, A, Nitsan, Z 1985. Evaluation of simultaneous selection for live body weight and against abdominal fat in broilers. Poultry Science 64, 12571263.
Collin, A, Swennen, Q, Skiba-Cassy, S, Buyse, J, Chartrin, P, Le Bihan-Duval, E, Crochet, S, Duclos, MJ, Joubert, R, Decuypere, E, Tesseraud, S 2009. Regulation of fatty acid oxidation in chicken (Gallus gallus): interactions between genotype and diet composition. Comparative Biochemistry and Physiology Part B 153, 171177.
Daval, S, Lagarrigue, S, Douaire, M 2000. Messenger RNA levels and transcription rates of hepatic lipogenesis genes in genetically lean and fat chickens. Genetics, Selection and Evolution 32, 521531.
Demeure, O, Duclos, MJ, Bacciu, N, Le Mignon, S, Filangi, O, Pitel, F, Boland, A, Lagarrigue, S, Cogburn, L, Simon, J, Le Roy, P, Le Bihan-Duval, E 2013. Genome-wide interval mapping using SNP identifies new QTL for growth, body composition and several physiological parameters in an F2 intercross between fat and lean chicken lines. BMC Genomics, submitted.
Dupont, J, Chen, JW, Derouet, M, Simon, J, Leclercq, B, Taouis, M 1999. Metabolic differences between genetically lean and fat chickens are partly attributed to the alteration of insulin signaling in liver. Journal of Nutrition 129, 19371944.
Géraert, PA, Leclercq, B, Larbier, M 1987. Effects of glucogenic amino acid supplementation on growth performance, body composition and plasma free amino acid levels in genetically lean and fat chickens. Reproduction Nutrition et Développement 27, 10411051.
Géraert, PA, Mac Leod, MG, Leclercq, B 1988. Energy metabolism in genetically fat and lean chickens: diet- and cold-induced thermogenesis. Journal of Nutrition 118, 12321239.
Géraert, PA, Guillaumin, S, Leclercq, B 1993. Are genetically lean broilers more resistant to hot climate. British Poultry Science 34, 643653.
Hermier, D, Chapman, MJ, Leclercq, B 1984. Plasma lipoprotein profile in fasted and reefed chickens of two strains selected for high or low adiposity. Journal of Nutrition 114, 11121121.
Hermier, D, Quignard-Boulange, A, Dugail, I, Guy, G, Salichon, MR, Brigant, L, Ardouin, B, Leclercq, B 1989. Evidence of enhanced storage capacity in adipose tissue of genetically fat chickens. Journal of Nutrition 119, 13691375.
Jlali, M, Gigaud, V, Metayer-Coustard, S, Sellier, N, Tesseraud, S, Le Bihan-Duval, E, Berri, C 2012. Modulation of glycogen and breast meat processing ability by nutrition in chickens: impact of crude protein level in two chicken genotypes. Journal of Animal Science 90, 447455.
Lagarrigue, S, Pitel, F, Carre, W, Abasht, B, Le Roy, P, Neau, A, Amigues, Y, Sourdioux, M, Simon, J, Cogburn, L, Aggrey, S, Leclercq, B, Vignal, A, Douaire, M 2006. Mapping quantitative trait loci affecting fatness and breast muscle weight in meat-type chicken lines divergently selected on abdominal fatness. Genetics, Selection and Evolution 38, 8597.
Leclercq, B 1983. The influence of dietary protein content on the performance of genetically lean or fat growing chickens. British Poultry Science 24, 581587.
Leclercq, B 1986. Observations on reciprocal F1 crosses between fat and lean lines of chickens. Archiv für Geflügelkunde 50, 129131.
Leclercq, B 1988. Genetic selection of meat-type chickens for high or low abdominal fat content. In Leanness in domestic birds: genetic, metabolic and hormonal aspects (ed. B Leclercq and CC Whitehead), pp. 2540. Butterworths & Co., Ltd-INRA, London, UK.
Leclercq, B, Simon, J 1982. Selecting broilers for low or high abdominal fat: observations on the hens during the breeding period. Annales de zootechnie 31, 161170.
Leclercq, B, Guy, G 1991. Further investigations on protein requirement of genetically lean and fat chickens. British Poultry Science 32, 789798.
Leclercq, B, Blum, JC, Boyer, JP 1980. Selecting broilers for low or high abdominal fat: initial observations. British Poultry Science 21, 107113.
Leclercq, B, Hermier, D, Salichon, MR 1984. Effects of age and diet on plasma lipid and glucose concentrations in genetically lean or fat chickens. Reproduction, Nutrition et Développement 24, 5361.
Leclercq, B, Kouassi-Kouakou, J, Simon, J 1985. Laying performances, egg composition and glucose tolerance of genetically lean or fat meat-type breeders. Poultry Science 64, 16091616.
Leclercq, B, Simon, J, Ricard, FH 1987. Effects of selection for high and low blood plasma glucose concentration in chickens. British Poultry Science 28, 557565.
Leclercq, B, Guy, G, Rudeaux, F 1988a. Thyroid hormones in genetically lean or fat chickens: effects of age triiodothyronine supplementation. Reproduction, Nutrition et Développement 28, 931937.
Leclercq, B, Hermier, D, Guy, G 1990. Metabolism of very low-density lipoproteins in genetically lean or fat lines of chicken. Reproduction Nutrition Development 30, 701715.
Leclercq, B, Chevalier, B, Derouet, M, Simon, J 1988b. In vitro sensitivity of adipocytes from lean or fat chickens to glucagon and to an analogue of adenosine. In: Leanness in domestic birds: genetic, metabolic and hormonal aspects (ed. B Leclercq and CC Whitehead), pp. 239242. Butterworths & Co., Ltd-INRA, London, UK.
Leclercq, B, Chagneau, AM, Cochard, T, Hamzaoui, S, Larbier, M 1993. Comparative utilization of sulphur-containing amino-acids by genetically lean or fat chickens. British Poultry Science 34, 383391.
Leenstra, FR, Pit, R 1987. Fat deposition in a broiler sire strain. 2. Comparisons among lines selected for less abdominal fat, lower feed conversion ratio and higher body weight after restricted and ad libitum feeding. Poultry Science 66, 193202.
Legrand, P, Lemarchal, P 1988. Hepatic Δ9 desaturating activity in genetically lean and fat chickens. In Leanness in domestic birds: genetic, metabolic and hormonal aspects (ed. B Leclercq and CC Whitehead), pp. 233234. Butterworths & Co., Ltd-INRA, London, UK.
Le Mignon, S, Pitel, F, Gilbert, H, Le Bihan-Duval, E, Vignoles, F, Demeure, O, Lagarrigue, S, Simon, J, Cogburn, L, Aggrey, S, Douaire, M, Le Roy, P 2009. A comprehensive analysis of QTL for abdominal fat and breast muscle weights on chicken chromosome 5 using a multivariate approach. Animal Genetics 40, 157164.
Lilburn, MS, Leach, RM, Buss, EG, Martin, RJ 1982. The developmental characteristics of two strains of chickens selected for differences in mature abdominal fat pad size. Growth 46, 171181.
Picaper, G, Leclercq, B, Saadoun, A, Mongin, P 1986. A radioimmunoassay of chicken growth hormone produced by recombinant DNA technology: validation and observations of plasma hormone variations in genetically fat and lean chickens. Reproduction, Nutrition et Développement 26, 11051114.
Pym, RAE, Solvyns, AJ 1979. Selection for food conversion in broilers: body composition of birds selected for increased body weight, food consumption and food conversion ratio. British Poultry Science 20, 8797.
Pym, RAE, Leclercq, B, Tomas, FM, Tesseraud, S 2004. Protein utilisation and turnover in lines of chickens selected for different aspects of body composition. British Poultry Science 45, 775786.
Ricard, FH, Rouvier, R 1969. Etude de la composition anatomique du poulet. II. Variabilité de la répartition des différentes parties corporelles dans une souche de type Cornish. Annales de Génétique et de Sélection Animale 1, 151165.
Ricard, FH, Leclercq, B 1984. Similitude de la composition des lipides intramusculaires chez des poulets génétiquement maigres ou gras. Annales de Génétique et Sélection 16, 127130.
Ricard, FH, Touraille, C 1988. Selection for leanness and carcass quality. In Leanness in domestic birds: genetic, metabolic and hormonal aspects (ed. B Leclercq and CC Whitehead), pp. 377386. Butterworths & Co., Ltd-INRA, London, UK.
Ricard, FH, Leclercq, B, Marché, G 1982. Rendement en viande de poulets de deux lignées sélectionnées sur l’état d'engraissement. Annales de Génétique et Sélection Animale 14, 551556.
Ricard, FH, Leclercq, B, Touraille, C 1983. Selecting broilers for low and high abdominal fat, distribution of carcass fat and quality of meat. British Poultry Science 24, 511516.
Rideau, N, Simon, J, Leclercq, B 1986. Further characterization of insulin secretion from the perfused duodenum-pancreas of chicken: a comparison of insulin release in chickens selected for high and low abdominal fat content. Endocrinology 119, 26352640.
Saadoun, A, Leclercq, B 1986. In vivo lipogenesis in genetically fat and lean chickens of various ages. Comparative Biochemistry and Physiology 83B, 607611.
Saadoun, A, Leclercq, B 1987. In vivo lipogenesis of genetically lean and fat chickens: effects of nutritional state and dietary fat. Journal of Nutrition 17, 428435.
Saadoun, A, Simon, J, Leclercq, B 1987. Effect of exogenous corticosterone in genetically fat and lean chickens. British Poultry Science 28, 519528.
Saadoun, A, Simon, J, Williams, J, Leclercq, B 1988. Levels of insulin, corticosterone, T3, T4 and insulin sensitivity in fat and lean chickens. Diabète et Métabolisme 14, 97103.
Sibut, V, Le Bihan-Duval, E, Tesseraud, S, Godet, E, Bordeau, T, Cailleau-Audouin, E, Chartrin, P, Duclos, MJ, Berri, C 2008. Adenosine monophosphate-activated protein kinase involved in variations of muscle glycogen and breast meat quality between lean and fat chickens. Journal of Animal Science 86, 28882896.
Simon, J, Leclercq, B 1982. Longitudinal study of adiposity in chickens selected for high of low abdominal fat content: further evidence of a glucose-insulin imbalance in the fat line. Journal of Nutrition 112, 19611973.
Simon, J, Leclercq, B 1985. Fat and lean chickens: prefattening period and in vivo sensitivity to insulin, atropine and propranolol. American Journal of Physiology 18, R393R401.
Simon, J, Chevalier, B, Derouet, M, Leclercq, B 1991. Normal number and kinase activity of insulin-receptors in liver of genetically fat chickens. Journal of Nutrition 121, 379385.
Skiba-Cassy, S, Collin, A, Chartrin, P, Medale, F, Simon, J, Duclos, MJ, Tesseraud, S 2007. Chicken liver and muscle carnitine palmitoyltransferase 1: nutritional regulation of messengers. Comparative Biochemistry and Physiology, Part B 147, 278287.
Swennen, Q, Janssens, GPJ, Collin, A, Le Bihan-Duval, E, Verbeke, K, Decuypere, E, Buyse, J 2006. Diet-induced thermogenesis and glucose oxidation in broiler chickens: influence of genotype and diet composition. Poultry Science 85, 731742.
Williams, J, Harvey, S, Leclercq, B 1986. Plasma levels of luteinizing hormone, growth hormone and estradiol from six weeks of age to sexual maturity in two lines of chickens selected for low or high abdominal fat content. Poultry Science 65, 17821786.
Whitehead, CC, Griffin, HD 1984. Development of divergent lines of lean and fat broilers using plasma very low density lipoprotein concentration as a selection criterion: the first three generations. British Poultry Science 25, 573582.

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Chicken lines divergent for low or high abdominal fat deposition: a relevant model to study the regulation of energy metabolism

  • E. Baéza (a1) and E. Le Bihan-Duval (a1)

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