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Chapter 4 - The Importance of the Correlation between Radiology and Pathology in Shaken Baby Syndrome

from Section 2 - Medicine

Published online by Cambridge University Press:  07 June 2023

Keith A. Findley
Affiliation:
University of Wisconsin, Madison
Cyrille Rossant
Affiliation:
University College London
Kana Sasakura
Affiliation:
Konan University, Japan
Leila Schneps
Affiliation:
Sorbonne Université, Paris
Waney Squier
Affiliation:
John Radcliffe Hospital, Oxford
Knut Wester
Affiliation:
Universitetet i Bergen, Norway
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Summary

This chapter focuses on the correlation of radiologic imaging with pathologic findings in infants and children with brain insults. Imaging is usually obtained while the child is alive, often shortly after a change in mental status. The imaging studies can therefore serve as a powerful tool to diagnose alterations of the macroscopic anatomy contributing to brain dysfunction. It is often not the anatomic abnormalities seen on imaging that are disagreed upon in cases of suspected shaken baby syndrome (SBS) or abusive head trauma (AHT); instead, the disagreements centre around what conclusions can be drawn from the anatomic alterations that have been identified. This chapter explores the strengths and weaknesses of radiologic imaging in the context of suspected AHT and emphasises the importance of understanding the pathologic basis of diagnoses made on imaging studies.

Type
Chapter
Information
Shaken Baby Syndrome
Investigating the Abusive Head Trauma Controversy
, pp. 66 - 84
Publisher: Cambridge University Press
Print publication year: 2023

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References

Wintermark, M, Lepori, D, Cotting, J et al. Brain perfusion in children: Evolution with age assessed by quantitative perfusion computed tomography. Pediatrics. 2004;113(6):1642–52.CrossRefGoogle ScholarPubMed
Scheimberg, I, Cohen, MC, Vazquez, REZ et al. Nontraumatic intradural and subdural hemorrhage and hypoxic ischemic encephalopathy in fetuses, infants, and children up to three years of age: Analysis of two audits of 636 cases from two referral centers in the United Kingdom. Pediatric and Developmental Pathology. 2013;16(3):149–59.Google Scholar
Kumar, R, Singhal, N, Mahapatra, AK. Traumatic subdural effusions in children following minor head injury. Child’s Nervous System. 2008;24(12):1391–6.Google Scholar
Vinchon, M, Joriot, S, Jissendi-Tchofo, P, Dhellemmes, P. Postmeningitis subdural fluid collection in infants: Changing pattern and indications for surgery. Journal of Neurosurgery. 2006;104(6 Suppl):383–7.Google Scholar
Roach, ES, Golomb, MR, Adams, R et al. Management of stroke in infants and children: A scientific statement from a Special Writing Group of the American Heart Association Stroke Council and the Council on Cardiovascular Disease in the Young. Stroke. 2008;39(9):2644–91.Google Scholar
Hellbusch, LC. Benign extracerebral fluid collections in infancy: Clinical presentation and long-term follow-up. Journal of Neurosurgery: Pediatrics. 2007;107(2):119–25.Google Scholar
Zahl, SM, Egge, A, Helseth, E, Wester, K. Benign external hydrocephalus: A review, with emphasis on management. Neurosurgery Review. 2011;34(4):417–32.Google Scholar
Caldarelli, M, Di Rocco, C, Romani, R. Surgical treatment of chronic subdural hygromas in infants and children. Acta Neurochirurgica (Wien). 2002;144(6):581–8.Google Scholar
Park, CK, Choi, KH, Kim, MC, Kang, JK, Choi, CR. Spontaneous evolution of posttraumatic subdural hygroma into chronic subdural haematoma. Acta Neurochirurgica (Wien). 1994;127(1–2):41–7.Google Scholar
Klostranec, JM, Vucevic, D, Bhatia, KD et al. Current concepts in intracranial interstitial fluid transport and the glymphatic system: Part I. Anatomy and physiology. Radiology. 2021;301(3):502–14.Google Scholar
Squier, W, Mack, J, Green, A, Aziz, T. The pathophysiology of brain swelling associated with subdural hemorrhage: The role of the trigeminovascular system. Child’s Nervous System. 2012;28:2005–15.Google Scholar
Choudhary, AK, Servaes, S, Slovis, TL et al. Consensus statement on abusive head trauma in infants and young children. Pediatric Radiology. 2018;48(8):1048–65.Google Scholar
Zouros, A, Bhargava, R, Hoskinson, M, Aronyk, KE. Further characterization of traumatic subdural collections of infancy: Report of five cases. Journal of Neurosurgery: Pediatrics. 2004;100(5):512–18.Google Scholar
McConnell, AA. Traumatic subdural effusions. Journal of Neurology, Neurosurgery and Psychiatry. 1941;4(3–4):237–56.Google Scholar
Bradley, WG. MR appearance of hemorrhage in the brain. Radiology. 1993;189(1):1526.Google Scholar
Sieswerda-Hoogendoorn, T, Postema, FAM, Verbaan, D, Majoie, CB, Van Rijn, RR. Age determination of subdural hematomas with CT and MRI: A systematic review. European Journal of Radiology. 2014;83(7):1257–68.Google Scholar
Vezina, G. Assessment of the nature and age of subdural collections in nonaccidental head injury with CT and MRI. Pediatric Radiology. 2009;39(6):586–90.Google Scholar
Sebire, G. Cerebral venous sinus thrombosis in children: Risk factors, presentation, diagnosis and outcome. Brain. 2005;128(3):477–89.Google Scholar
Bordia, R, Le, M, Behbahani, S. Pitfalls in the diagnosis of subdural hemorrhage: Mimics and uncommon causes. Journal of Clinical Neuroscience. 2021;89:7184.Google Scholar
Krasnokutsky, MV. Cerebral venous thrombosis: A potential mimic of primary traumatic brain injury in infants. American Journal of Roentgenology. 2011;197(3):W503–7.Google Scholar
Canedo-Antelo, M, Baleato-González, S, Mosqueira, AJ et al. Radiologic clues to cerebral venous thrombosis. RadioGraphics. 2019;39(6):1611–28.Google Scholar
Poon, CS, Chang, J-K, Swarnkar, A, Johnson, MH, Wasenko, J. Radiologic diagnosis of cerebral venous thrombosis: Pictorial review. American Journal of Roentgenology. 2007;189(6_supplement):S6475.Google Scholar
Garrido-Barbero, M, Arnaez, J, Loureiro, B et al. The role of Factor V Leiden, Prothrombin G20210A, and MTHFR C677 T mutations in neonatal cerebral sinovenous thrombosis. Clinical and Applied Thrombosis. 2019;25:107602961983435.Google Scholar
Anderst, J, Carpenter, S, Frazier, T et al. Subdural hemorrhage in a cohort with cerebral sinovenous thrombosis: Application to abusive head trauma. Child Abuse and Neglect. 2021;117:105119.CrossRefGoogle Scholar
McLean, LA, Frasier, LD, Hedlund, GL. Does intracranial venous thrombosis cause subdural hemorrhage in the pediatric population? American Journal of Neuroradiology. 2012;33(7):1281–4.Google Scholar
Vaslow, DF. Chronic subdural hemorrhage predisposes to development of cerebral venous thrombosis and associated retinal hemorrhages and subdural rebleeds in infants. Neuroradiology Journal. 2021;197140092110269.Google Scholar
Adamsbaum, C, Rambaud, C. Abusive head trauma: Don’t overlook bridging vein thrombosis. Pediatric Radiology. 2012;42(11):12981300.CrossRefGoogle ScholarPubMed
Rambaud, C. Bridging veins and autopsy findings in abusive head trauma. Pediatric Radiology. 2015;45(8):1126–31.Google Scholar
Zahl, SM, Mack, JA, Rossant, C, Squier, W, Wester, K. Thrombosis is not a marker of bridging vein rupture in infants with alleged abusive head trauma. Acta Paediatrica. 2021;110(10):2686–94.Google Scholar
Goodrich, JT. Reprint of ‘Concerning surgical intervention for the intracranial hemorrhages of the new-born’ by Harvey Cushing, M.D. Child’s Nervous System. 2000;16(8):484–92.Google Scholar
Choudhary, AK, Bradford, R, Dias, MS, Thamburaj, K, Boal, DKB. Venous injury in abusive head trauma. Pediatric Radiology. 2015;45(12):1803–13.Google Scholar
Hahnemann, ML, Kinner, S, Schweiger, B et al. Imaging of bridging vein thrombosis in infants with abusive head trauma: The ‘tadpole sign’. European Radiology. 2015;25(2):299305.Google Scholar
Hymel, KP, Stoiko, MA, Herman, BE et al. Head injury depth as an indicator of causes and mechanisms. Pediatrics. 2010;125(4):712–20.Google Scholar
Squier, W, Austin, T, Anslow, P, Weller, RO. Infant subcortical cystic leucomalacia: A distinct pathological entity resulting from impaired fluid handling. Early Human Development. 2011;87(6):421–6.Google Scholar
Choudhary, AK, Ishak, R, Zacharia, TT, Dias, MS. Imaging of spinal injury in abusive head trauma: A retrospective study. Pediatric Radiology. 2014;44(9):1130–40.Google Scholar
Choudhary, AK, Bradford, RK, Dias, MS, Moore, GJ, Boal, DKB. Spinal subdural hemorrhage in abusive head trauma: A retrospective study. Radiology. 2012;262(1):216–23.Google Scholar
Koumellis, P, McConachie, NS, Jaspan, T. Spinal subdural haematomas in children with non-accidental head injury. Archives of Disease in Childhood. 2009;94(3):216–19.Google Scholar

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