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Improvement of medication compliance in uncontrolled hypertension

from Section 6 - Behavioural interventions in medicine

Published online by Cambridge University Press:  05 August 2016

R. B. Haynes
Affiliation:
McMaster University Medical Centre
D. L. Sackett
Affiliation:
McMaster University Medical Centre
E. S. Gibson
Affiliation:
McMaster University Medical Centre
D. W. Taylor
Affiliation:
McMaster University Medical Centre
B. C. Hackett
Affiliation:
McMaster University Medical Centre
R. S. Roberts
Affiliation:
McMaster University Medical Centre
A. L. Johnson
Affiliation:
McMaster University Medical Centre
Andrew Steptoe
Affiliation:
St George's Hospital Medical School, University of London
Jane Wardle
Affiliation:
Imperial Cancer Research Fund, London
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Summary

Summary

38 hypertensive Canadian steelworkers who were neither compliant with medications nor at goal diastolic blood-pressure six months after starting treatment were allocated either to a control group or to an experimental group who were taught how to measure their own blood-pressures, asked to chart their home blood-pressures and pill taking, and taught how to tailor pill taking to their daily habits and rituals; these men were also seen fortnightly by a high-school graduate with no formal health professional training who reinforced the experimental manoeuvres and rewarded improvements in compliance and blood-pressure. Six months later, average compliance had fallen by 1.5% in the control group but rose 21.3% in the experimental group. Blood-pressures fell in 17 of 20 experimental patients (to goal in 6) and in 10 of 18 control patients (to goal in 2).

Introduction

The potential benefit of vigorous medical treatment for hypertension often remains out of reach, in part because the patient does not comply with treatment. We believe that this non-compliance is a major barrier to the effective control of hypertension and that our understanding of this phenomenon is primitive. In phase I of a trial of strategies for improving compliance we found that neither the mastery of facts about hypertension nor receiving care and follow-up at work in “company time” led to any improvement. We describe here the second phase of this trial in which the application of more behaviourally oriented strategies did lead to improvements in both compliance and blood-pressure control.

Methods

These have been described in detail elsewhere. Briefly, the examination of 5400 men at Dominion Foundries and Steel Company (over 95% of a random two-thirds sample of male employees) yielded 245 who had high blood-pressures (when sitting quietly on three separate days, a standard series of fifth-phase diastolic blood-pressure were ≥95 mm Hg), were free of remediable forms of hypertension, were taking no daily medications (70 men were on treatment and were therefore excluded), and had not been treated for hypertension in the preceding six months.

In phase I of this trial, men were randomly allocated into a factorial design in order to test strategies affecting either the convenience of their follow-up care or their knowledge about hypertension and its treatment.

Type
Chapter
Information
Psychosocial Processes and Health
A Reader
, pp. 457 - 467
Publisher: Cambridge University Press
Print publication year: 1994

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