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Chapter 38 - Safe and Effective Cryostorage of Embryos for IVF

from Section 7 - Embryo Cryopreservation

Published online by Cambridge University Press:  07 August 2023

By
Mitchel C. Schiewe
Edited by
Markus H. M. Montag  and
Dean E. Morbeck
Markus H. M. Montag
Affiliation:
ilabcomm GmbH, St Augustin, Germany
Dean E. Morbeck
Affiliation:
Kindbody Inc, New York City
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Summary

Cryobanking is a major component of today’s assisted reproductive technologies (ART). As Reproductive Biologists and Cryogenic Specialists, we are not only burdened with the accurate labelling, witnessing and use of cryopreserved specimens (the subject of other chapters in this text), we must ensure their safe and secure long-term storage. Based on a heightened awareness of actual and experimental tank failures, we will outline and discuss the critical components of effective quality management for cryostorage.

Keywords

cryopreservationstoragequality managementembryotank failure
Type
Chapter
Information
Principles of IVF Laboratory Practice
Laboratory Set-Up, Training and Daily Operation
 , pp. 278 - 286
Publisher: Cambridge University Press
Print publication year: 2023

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References

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Pomeroy, K. O., Reed, M. L., LoManto, B., et al. Cryostorge tank failures: temperature and volume loss over time after induced failure by removal of insulative vacuum. J Asst Reprod Genet 2019; 36(11):2271–8.Google ScholarPubMed
Campbell, L. D., Astrin, J. J., DeSouza, Y., et al. The 2018 Revision of the ISBER Best Practices: Summary of Changes and the Editorial Team’s Development Process. Biopreserv Biobanking 2018; 16(1): 3–6.CrossRefGoogle ScholarPubMed
International Society for Biological and Environmental Repositories (ISBER). Best Practices Addendum : Liquid Nitrogen-Based Cryogenic Storage of Specimens, 4th ed., pp. 1–103 (2019).Google Scholar
Schiewe, M. C., Freeman, M., Whitney, J. B., et al. Comprehesive assessment of cryogenic storage risk and quality management concerns: best practice guidelines for ART labs. J Asst Reprod Genet 2019; 36(1):4–15.Google Scholar
Michaelson, Z. P., Bondalapati, S. T., Amrane, S., et al. Early detection of cryostorage tank failure using a weight-based monitoring system. J Asst Reprod Genet 2019; 36(4):655–60.Google ScholarPubMed
Schiewe, M. C. Preventing cryostorage failure, in Cryostorage Management and the Lost Art of ART, ed. Schiewe, M. C., Pool, T., Fish, D., et al., pp. 70–9 (Am Soc Reprod Med 52nd Ann Pre-Congress, PC04, 2019).Google Scholar
Tomlinson, M. and Sakkas, D. Is a review of standard procedures for cryopreservation needed? Safe and effective cryopreservation: should sperm banks and fertility centres move toward storage in nitrogen vapour? Hum Reprod 2000; 15:2460–3.Google Scholar
Schiewe, M. C., Zozula, S., Ochoa, T., et al. Usefulness of remote, continuous weight determination for the routine quality management (QM) of cryodewar tanks, 75th Ann Amer Soc Reprod Med Mtg. Fertil Steril 2019; 112 (Suppl. 3):e269 (P-812).Google Scholar

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