Skip to main content Accessibility help
  • Get access
    Check if you have access via personal or institutional login
  • Cited by 5
  • Print publication year: 2010
  • Online publication date: February 2011

2 - The maternal and placental origins of chronic disease


1. BarkerDJP. Fetal origins of coronary heart disease. Br Med J 1995; 311: 171–4.
2. NICHD. Pregnancy and Perinatology Branch: Strategic Plan 2005–2010. NIH, 2003.
3. HardingJE. The nutritional basis of the fetal origins of adult disease. Int J Epidemiol 2001; 30: 15–23.
4. JacksonAA. All that glitters. Br Nutr Foundation Annual Lecture. Nutr Bull 2000; 25: 11–24.
5. JanssonT, PowellTL. Role of the placenta in fetal programming: underlying mechanisms and potential interventional approaches. Clin Sci 2007; 113: 1–13.
6. HamiltonWJ, BoydJD, MossmanHW. Human Embryology. Cambridge: W. Heffer & Sons, 1945.
7. SibleyCP. In Case RM, Waterhouse JM, eds. Human Physiology: Age, Stress, and the Environment. Oxford: Oxford University Press, 1994; 3–27.
8. McCrabbGJ, EganAR, HoskingBJ. Maternal undernutrition during mid-pregnancy in sheep: variable effects on placental growth. J Agric Sci 1992; 118: 127–32.
9. ErikssonJ, ForsenT, ToumilhetoJ, OsmondC, BarkerD. Fetal and childhood growth and hypertension in adult life. Hypertension 2000; 36: 790–4.
10. ForsénT, ErikssonJG, TuomilehtoJet al. Mother's weight in pregnancy and coronary heart disease in a cohort of Finnish men: follow up study. Br Med J 1997; 315: 837–40.
11. HinselmannH. Biologie und Pathologie des Weibes. Berlin: Urban & Schwarzenberg, 1925.
12. AndersonMC. Lessons in Midwifery for Nurses and Midwifes. London: A & C Black, 1930.
13. MaysM. An Introduction to Midwifery. London: Faber and Faber 1930.
14. BarkerDJP, ThornburgKL, OsmondC, KajantieE, ErikssonJG. The surface area of the placenta and hypertension in the offspring in later life. Int J Dev Biol 2010; 54: 525–30.
15. BarkerDJP, OsmondC, KajantieE, ErikssonJG. Growth and chronic disease: findings in the Helsinki Birth Cohort. Ann Hum Biol 2009; 36: 445–58.
16. RobertsJM, CooperDW. Pathogenesis and genetics of preeclampsia. Lancet 2001; 357: 53–6.
17. KajantieE, ThornburgK, ErikssonJG, OsmondC, BarkerDJP. In pre-eclampsia the placenta grows slowly along its minor axis. Int J Dev Biol 2010; 54: 469–73.
18. BarkerDJP, BullAR, OsmondC, SimmondsS. Fetal and placental size and risk of hypertension in adult life. Br Med J 1990; 301: 259–62.
19. MartynCN, BarkerDJP, OsmondC. Mothers pelvic size, fetal growth and death from stroke in men. Lancet 1996; 348: 1264–8.
20. McCrabbGJ, EganAR, HoskingBJ. Maternal undernutrition during mid-pregnancy in sheep. Placental size and its relationship to calcium transfer during late pregnancy. Br J Nutr 1991; 65: 157–68.
21. BurkhardT, SchafferL, SchneiderS, ZimmermanR, KurmanaviciusJ. Reference values for the weight of freshly delivered term placentas and for placental weight – birth weight ratios. Eur J Obstet Gynaecol 2006; 128: 248–52.
22. JanssonT, ThordsteinM, KjellmerI. Placental blood flow and fetal weight following uterine artery ligation. Biol Neonate 1986; 49: 172–80.
23. HafnerE, MetzenbauerM, HofingerDet al. Placental growth from the first to the second trimester of pregnancy in SGA-foetuses and pre-eclamptic pregnancies compared to normal foetuses. Placenta 2003; 24: 336–42.
24. GodfreyKM, RedmanCWG, BarkerDJP, OsmondC. The effect of maternal anaemia and iron deficiency on the ratio of fetal weight to placental weight. Br J Obstet Gynaecol 1991; 98: 886–91.
25. GodfreyKM. The role of the placenta in fetal programming. Placenta 2002; 23 (Suppl A): S20–S27.
26. RavelliACJ, Van Der MeulenJHP, MichelsRPJet al. Glucose tolerance in adults after prenatal exposure to the Dutch famine. Lancet 1998; 351: 173–7.
27. CampbellDM, HallMH, BarkerDJPet al. Diet in pregnancy and the offspring's blood pressure 40 years later. Br J Obstet Gynaecol 1996; 103: 273–80.
28. MooreVM, MillerAG, BoultonTJet al. Placental weight, birth measurements, and blood pressure at age 8 years. Arch Dis Child 1996; 74: 538–41.
29. TaylorSJC, WhincupPH, CookDG, PapacostaO, WalkerM. Size at birth and blood pressure; cross sectional study in 8–11 year old children. Br Med J 1997; 314: 475–80.
30. WhincupP, CookD, PapacostaO, WalkerM. Birth weight and blood pressure: cross sectional and longitudinal relations in childhood. Br Med J 1995; 311: 773–6.
31. TannerJM. Fetus Into Man. 2nd ed. Ware: Castlemead, 1989.
32. DugglebySL, JacksonAA. Relationship of maternal protein turnover and lean body mass during pregnancy and birth length. Clin Sci (Lond) 2001; 101: 65–72.
33. PesonenAK, RaikkonenK, HeinonenKet al. Depressive symptoms in adults separated from their parents as children: a natural experiment during World War II. Am J Epidemiol 2007; 166: 1126–33.
34. BarkerDJP, BagbyS, HansonMA. Mechanisms of disease: in utero programming in the pathogenesis of hypertension. Nature Clin Pract Nephrol 2006; 2: 700–7.
35. HillJC, KrishnaveniGV, AnnammaI, LearySD, FallCHD. Glucose tolerance in pregnancy in South India: relationship to neonatal anthropometry. Acta Obstet Gynaecol Scand 2005; 84: 159–65.
36. BarkerDJP, OsmondC, ForsénTJ, KajantieE, ErikssonJG. Trajectories of growth among children who have coronary events as adults. N Engl J Med 2005; 353: 1802–9.
37. ErikssonJG, ThornburgKL, OsmondC, KajantieE, BarkerDJP, The prenatal origins of lung cancer: I. The fetus. Am J Hum Biol 2010; 22: 508–11.
38. BarkerDJP, ThornburgKL, OsmondC, KajantieE, ErikssonJG. The prenatal origins of lung cancer: II. The placenta. Am J Hum Biol 2010; 22: 512–16.
39. EricssonA, SaljoK, SjostrandEet al. Brief hyperclycaemia in the early pregnant rat increases fetal weight at term by stimulating placental growth and affecting placental nutrient transport. J Physiol 2007; 581: 1323–32.
40. PedersenJF. Ultrasound evidence of sexual difference in fetal size in first trimester. Br Med J 1980; 281: 1253.
41. ForsénT, ErikssonJG, TuomilehtoJ, OsmondC, BarkerDJP. Growth in utero and during childhood among women who develop coronary heart disease: longitudinal study. Br Med J 1999; 319: 1403–7.
42. ErikssonJG, KajantieE, OsmondC, ThornburgK, BarkerDJP. Boys live dangerously in the womb. Am J Hum Biol 2010; 22: 330–5.
43. OunstedM, ScottA, OunstedC. Transmission through the female line of a mechanism constraining human fetal growth. Ann Hum Biol 1986; 13: 143–51.
44. RavelliAC, Van Der MeulenJHP, OsmondC, BarkerDJP, BlekerOP. Obesity at the age of 50 y in men and women exposed to famine prenatally. Am J Clin Nutr 1999; 70: 811–16.
45. OzakiT, NishinaH, HansonMA, PostonL. Dietary restriction in pregnant rats causes gender-related hypertension and vascular dysfunction in offspring. J Physiol 2001; 530: 141–52.
46. WoodsLL, IngelfingerJR, RaschR. Modest maternal protein restriction fails to program adult hypertension in female rats. Am J Physiol Regul Integr Comp Physiol 2005; 289: R1131–6.