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  • Print publication year: 2012
  • Online publication date: July 2012

7 - Sleep disturbance


Ancoli-Israel, S., Klauber, M.R., Jones, D.W., et al. (1997). Variations in circadian rhythms of activity, sleep, and light exposure related to dementia in nursing-home patients. Sleep, 20, 18–23.
Ancoli-Israel, S. and Vittiello, M. (2006). Sleep in dementia. American Journal of Geriatric Psychiatry, 14, 91–94.
Baskett, J.J, Broad, J.B., Wood, P.C., et al. (2003). Does melatonin improve sleep in older people? A randomised crossover trial, Age and Ageing, 32, 164–170.
Beaulieu-Bonneau, S. and Hudon, C. (2009). Sleep disturbances in older adults with mild cognitive impairment. International Psychogeriatrics, 21, 645–666.
Bliwise, D.L. (2004). Sleep disorders in Alzheimer’s disease and other dementias. Clinical Cornerstone, 6, S16–28.
Bombois, S., Derambure, P., Pasquier, F., et al. (2010). Sleep disorders in aging and dementia. Journal of Nutrition, Health & Aging, 14, 212–217.
Bonanni, E., Maestri, M., Tognoni, G. et al. (2005). Daytime sleepiness in mild and moderate alzheimer’s disease and its relationship with cognitive impairment, Journal of Sleep Research, 14, 311–317.
Chokroverty, S. (1996). Sleep and degenerative neurologic disorders. Neurologic Clinics, 14, 807–827.
Cole, C. and Richards, K. (2005). Sleep and cognition in people with Alzheimer’s disease. Issues in Mental Health Nursing, 26, 687–698.
Cole, C. and Richards, K. (2006). Sleep in persons with dementia: Increasing quality of life by managing sleep disorders. Journal of Gerontological Nursing, 32, 48–53.
Cooke, J. R., Loredo, J.S., Liu, L., et al. (2006). Acetycholinesterase inhibitors and sleep architecture in patients with Alzheimer’s disease. Drugs and Aging, 23, 503–511.
Craig, D., Hart, D., Passmore, A. (2006). Genetically increased risk of sleep disruption in Alzheimer’s disease. Sleep, 29, 1003–1007.
Creese, J., Bedard, M., Brazil, K., et al. (2008). Sleep disturbances in spousal caregivers of individuals with Alzheimer’s disease. International Psychogeriatrics, 20,149–161.
David, R., Zeitzer, J., Friedman, L., et al. (2010). Non pharmacological management of sleep disturbance in Alzheimer’s disease. The Journal of Nutrition, Health & Aging, 14, 203–206.
De Jonghe, A., Korevaar, J., Van Muster, B., et al. (2010). Effectiveness of melatonin treatment on circadian rhythm disturbances in dementia. Are there implications for delirium? A systematic review. International Journal of Geriatric Psychiatry, 25, 1201–1208.
Dowling, G.A., Hubbard, E. M., Mastick, J., et al. (2005). Effect of morning bright light treatment for rest-activity disruption in institutionalized patients with severe Alzheimer’s disease. International Psychogeriatrics, 17, 221–236.
Duran, J., Greenspan, A., Diago, J.I., et al. (2005). Evaluation of risperidone in the treatment of behavioural and psychological symptoms and sleep disturbances associated with dementia. International Psychogeriatrics, 17, 591–604.
Eggermont, L., Blankvoort, C., Scherder, E. (2010). Walking and night-time restlessness in mild-to-moderate dementia: a randomized controlled trial. Age and Aging, 39, 746–761.
Fetveit, A. and Bjorvatn, B. (2006). Sleep duration during the 24-hour day is associated with the severity of dementia in nursing home patients. International Journal of Geriatric Psychiatry, 21, 945–950.
Fetveit, A., Skjerve, A., Bjorvatn, B. (2003). Bright light treatment improves sleep in institutionalized elderly-an open trial. International Journal of Geriatric Psychiatry, 18, 520–526.
Fontana Gasio, P., Krauchi, K., Cajochen, C., et al. (2003). Dawn-dusk simulation light therapy of disturbed circadian rest-activity cycles in demented elderly. Experimental Gerontology, 38, 207–216.
Forbes, D., Morgan, D.G., Bangma, J., et al. (2009). Light therapy for managing sleep, behaviour, and mood disturbances in dementia (review). The Cochrane Library, 4. Available at: [Accessed February 15, 2012].
Gabelle, A. and Dauvilliers, Y. (2010). Sleep and dementia, The Journal of Nutrition, Health & Aging, 14, 201–202.
Gagnon, J. F., Petit, D., Fantini, M.L., et al. (2006). REM sleep behaviour disorder and REM sleep without atonia in probable Alzheimer’s disease, Sleep, 29, 1321–1325.
Harper, D.G., Stopa, E.G., McKee, A.C., et al.(2001). Differential circadian rhythm disturbances in men with Alzheimer’s disease and frontotemporal degeneration, Archives of General Psychiatry, 58, 353–360.
Hatfield, C.F., Herbert, J., van Someren, E.J., et al. (2004). Disrupted daily activity/rest cycles in relation to daily cortisol rhythms of home-dwelling patients with early Alzheimer’s dementia. Brain, 127, 1061–1074.
Hornung, P., Danker-Hopfe, H., Heuser, I. (2005). Age-related changes in sleep and memory: Commonalities and interrelationships. Experimental Gerontology, 40, 279–285.
Howcroft, D. and Jones, R. (2004). Does modafinil have the potential to improve disrupted sleep patterns in patients with dementia?International Journal of Geriatric Psychiatry, 20, 492–495.
Kim, S., Song, H., Yoo, S. (2003). The effect of bright light on sleep and behaviour in dementia: An analytic review, Geriatric Nursing, 24, 239–243.
Lee, D., Morgan, K., Lindesay, J. (2007). Effect of institutional respite care on the sleep of people with dementia and their primary caregiver. Journal of the American Geriatrics Society, 55, 252–258.
Lee, D. and Thomas, A. (2011). Sleep in dementia and caregiving- assessment and treatment implications: A review. International Psychogeriatrics, 23, 190–201.
Lee, J.H., Bliwise, D.L., Ansari, F.P., et al. (2007). Daytime sleepiness and functional impairment in Alzheimer’s disease. The American Journal of Geriatric Psychiatry, 15, 620–626.
McCurry, S., Gibbons, L.E., Logsdon, R.G., et al. (2003). Training caregivers to change the sleep hygiene practices of patients with dementia: the NITE-AD project. Journal of the American Geriatrics Society, 51, 1455–1460.
McCurry, S.Gibbons, L.E., Logsdon, R.G., et al. (2005). Nighttime insomnia treatment and education for Alzheimer’s disease: a randomized, controlled trial. Journal of the American Geriatrics Society, 53, 793–802.
McCurry, S., Gibbons, L.E., Logsdon, R.G., et al. (2007). Factors associated with caregiver reports of sleep disturbances in persons with dementia. The American Journal of Geriatric Psychiatry, 14, 112–120.
Moran, M., Lynch., C.A., Walsh, C. et al. (2005). Sleep disturbance in mild to moderate Alzheimer’s disease, Sleep Medicine, 6, 347–352.
Obadinia, S., Noroozian, M., Shahsavand, S., et al. (2004). Evaluation of insomnia and daytime napping in Iranian Alzheimer’s disease patients. The American Journal of Geriatric Psychiatry, 12, 517–522.
Paavilainen, P., Korhonen, I., Lotjonen, J., et al. (2005). Circadian activity rhythm in demented and non-demented nursing home residents measured by telemetric actigraphy. Journal of Sleep Research, 14, 61–68.
Pandi-Perumal, S., Zisapel, N., Srinivasn, V., et al. (2005). Melatonin and sleep in aging population, Experimental Gerontology, 40, 911–925.
Rao, V.Spiro, J., Samus, Q.M., et al. (2008). Insomnia and daytime sleepiness in people with dementia residing in assisted living: findings from the Maryland Assisted Living Study. International Journal of Geriatric Psychiatry, 23, 199–206.
Richards, K., Beck, C., O’Sullivan, P., et al. (2005). Effect of individual social activity on sleep in nursing home residents with dementia. Journal of the American Geriatrics Society, 53, 1510–1517.
Riemersma-van der Lek, R., Swaab, D., Twisk, J., et al. (2008). Effect of bright light and melatonin on cognitive and noncognitive function in elderly residents of group care facility. Journal of the American Medical Association, 299, 2642–2655.
Rongve, A., Boeve, B., Aarsland, D. (2010). Frequency and correlates of caregiver-reported sleep disturbances in a sample of persons with early dementia, Journal of the American Geriatrics Society, 58, 480–486.
Rowe, M., Kairalla, J., McCrae, C. (2010). Sleep in dementia caregivers and the effect of a night time monitoring system. Journal of Nursing Scholarship, 42, 338–347.
Singer, C., Tractenberg, R.E., Kaye, J., et al. (2003). A multicenter, placebo-controlled trial of melatonin for sleep disturbances in Alzheimer’s disease, Sleep, 26, 893–901.
Sullivan, S. and Richards, K. (2004). Predictions of circadian sleep-wake rhythm maintenance in elders with dementia. Aging & Mental Health, 8,143–152.
Tractenberg, R., Singer, C., Kaye, J. (2005a). Characterizing sleep problems in persons with Alzheimer’s disease and normal elderly. Journal of Sleep Research, 15, 97–103.
Tractenberg, R., Singer, C., Kaye, J. (2005b). Symptoms of sleep disturbance in persons with Alzheimer’s disease and normal elderly. Journal of Sleep Research, 14, 177–185.
Van Dijk, K., Lijpen, M.W., Van Someren, E.J., et al. (2006). Peripheral electrical nerve stimulation and rest-activity rhythm in Alzheimer’s disease. Journal of Sleep Research, 15, 415–423.
Yesavage, J., Friedman, L., Kraemer, H., et al. (2003). Sleep/wake disruption in Alzheimer’s disease: APOE status and longitudinal course. Journal of Geriatric Psychiatry and Neurology, 17, 20–24.